KEGG   Daphnia pulicaria: 124343456
Entry
124343456         CDS       T08670                                 
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic-like isoform X1
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
dpz  Daphnia pulicaria
Pathway
dpz00670  One carbon pool by folate
dpz01100  Metabolic pathways
dpz01240  Biosynthesis of cofactors
dpz04981  Folate transport and metabolism
Module
dpz_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:dpz00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    124343456
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    124343456
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dpz04147]
    124343456
Enzymes [BR:dpz01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     124343456
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     124343456
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     124343456
Exosome [BR:dpz04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   124343456
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 124343456
NCBI-ProteinID: XP_046652727
LinkDB
Position
6:complement(15951407..15956346)
AA seq 969 aa
MNFVVCVLKDTVKSWKNFSGSIYREFSISNHLIMEQYGQLLSGTEVAKNIRAALAEQVKQ
LKEQCSGFTPGLTIIQVGAREDSNVYIRMKMKAAEEIGIKATHTVLPSSTTQAELLRILN
KINLDPSVHGIIVQMPLDSVNVIDSTLITDSVNPSKDVDGLNTINQGKLAVGDLASGFLP
CTPNGCMELIKRTGIQIEGSQAVVIGRSKIVGTPAAELLKWHNATVTVCHSKTKNLPEVV
SGADILIVGIGQPNMVKGDWIKQGAVVIDCGINSIPDPTKASGSRLVGDVDFETAKMKSS
WITPVPGGVGPMTVAMLMKNTVIAAQKAAFKLSNTQWNLSLLPLKLSEPVPRDIDIARSQ
TPKNVMELAEEIGLSMSDVELYGSTKAKVNINILERLAEKPLGKYVIVCGITPTPLGEGK
STTTIGLSQAIGAHLKKNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDI
HAITAANNLLAAQIEARMFHEATQSDKALYARLVPKDKGTRKFSAIQVRRLTKLGINKSD
PDSLTDEEIHNFARLDIDPTTITWQRVMDTNDRFLRKIRVGLSDTEKGHERDCQFDISVA
SEIMAVLALTTGYADFRSRLGQMVVASSKQGVPITADDLGASGALMVLMKDAIHPTLMQT
LEGTPVFVHAGPFANIAHGNSSIIADQIALRLVGREGFVLTEAGFGADIGLEKFIHIKCR
ASGLKPDVVVLVATVRALKMHGGGPQVVPGNPIPAAYLEPNCALVETGFSNLKKHIENIR
KFGLQVVVAINRFTTDSDEELGFLQRLCKENGAFDAVVCSHWATGSQGAATLAEAVAKAA
EQPSDFRYLYDLEQSIEEKIEVIAKEVYGAEKIEISPAAKVQIERYKLQGFNNFPICMAK
THLSLSHDPSLKGAPTGFTLPIREVRASVGAGFLYPLVGTMSTMPGLPTRPAIFDIDLNL
ETGNIEGLF
NT seq 2910 nt   +upstreamnt  +downstreamnt
atgaactttgtagtctgcgtcttgaaagacacagtaaagtcgtggaaaaatttctcagga
agtatctacagagagttttcaatttccaaccatcttataatggagcaatacggtcaattg
ctttctggcacggaagttgcaaaaaatatcagagctgctttggctgaacaagttaaacaa
ctgaaagaacaatgttctggctttactcctggacttacaatcattcaagtgggtgctcga
gaagattcaaatgtctacattcgaatgaaaatgaaagctgctgaagaaattggtattaaa
gccacacatactgtccttccatcttcaactactcaagctgagcttctcagaatactcaat
aaaattaacttggaccctagtgtccatggcataattgtgcaaatgccattggattctgtg
aatgtgattgattctactctcatcacagattcagtaaacccaagcaaagatgttgatgga
ttaaatactattaatcagggaaaactagctgttggggatttagcttctgggtttcttcct
tgtactccaaatggctgcatggaattaatcaaaagaacagggatacaaattgagggaagc
caagcagttgttattggacggagtaagattgtcggaactcctgctgccgaacttctaaaa
tggcataatgcaactgttacagtttgtcattcaaaaacaaaaaacttgcctgaagtggtt
tctggtgcagacatacttatcgttggtattggacagccaaatatggtaaaaggagactgg
ataaagcaaggtgcagttgtgatagattgcggcatcaattctattccagatccgacaaag
gcgtcaggttctaggttggtgggagatgtagattttgaaactgctaaaatgaaatccagt
tggattactccagttcctggtggagttggtccaatgacggtagccatgcttatgaaaaat
acagttattgctgctcaaaaagcagcgttcaaactatccaatacccaatggaacttatcc
cttctgccacttaagttgagcgaaccagtaccgcgagatatcgatatagctcgtagccaa
accccgaaaaatgtcatggaattggctgaagaaatcggattatctatgtccgatgttgag
ctatatggttccacaaaagccaaagttaacatcaacattttggaacgtttggctgaaaaa
cccctcggaaaatacgtcattgtttgtggaataactccaacgccattaggagaaggaaaa
tcaactacgacaatcggtctatctcaagcaatcggtgctcatttgaaaaagaatgtgttt
gcttgtgtgaggcaaccttctcaaggaccaacctttgggatcaaagggggtgcggcggga
ggtggatactctcaagttattcccatggaagagttcaatttgcatttgaccggtgatatc
catgcaatcacggctgccaataatcttcttgccgctcaaattgaagctcgaatgtttcat
gaagcaactcaatcagataaagccttgtatgctcgccttgtgccaaaggataaaggcaca
cgcaaattttcagctattcaagtaagacgattaactaagctgggcatcaacaaatctgac
cctgattcattaactgatgaagaaattcacaattttgctcgtctagatatcgatcccaca
actattacttggcaaagagttatggatacgaacgacagatttttacgtaagattcgagtt
gggttgagcgatacggaaaagggacatgagcgtgattgtcaattcgatatttccgtagca
agtgaaataatggcagttttagctttgaccacaggttatgctgatttccgatcccgattg
ggccaaatggtagtagcctctagtaaacaaggagtaccgataaccgctgatgatttgggt
gcaagtggtgctttgatggtgctgatgaaagatgctattcatccgactctgatgcaaacg
cttgaaggaaccccggtctttgtacatgccggaccatttgccaatattgcacatggaaat
tcgtctattatagcagaccagattgcactacgattagtaggccgcgaaggatttgttttg
acagaagcaggattcggagcagatataggattggaaaagttcatccatatcaaatgtaga
gcttcaggtttgaaaccagatgttgtcgtcttggttgctacagtacgtgctctgaaaatg
catggtggtggtcctcaggttgttccaggaaatccaattccagctgcgtatttagagccc
aactgcgcattagtggaaacagggttttctaatcttaaaaaacatattgaaaacatacgg
aaatttggtctgcaagtcgttgttgcaatcaatcgtttcacgacggattcagacgaagaa
ctgggtttcctccagcgtttgtgtaaagaaaatggagcatttgatgctgtagtttgctca
cactgggcgactggcagtcaaggagctgcgaccttagcggaagcggttgccaaagctgct
gaacagccgtctgattttaggtatttgtatgacttggaacaatcaattgaagaaaaaatt
gaagtcatcgctaaggaagtctatggcgccgaaaaaatcgaaatatctcctgcagctaag
gttcaaatcgaacgctacaagcttcagggatttaataatttcccaatctgtatggcgaaa
actcacttatcgttgtcgcacgacccttcactaaaaggagctcctactggcttcactctc
ccaattcgagaagtgagagctagtgttggagccggatttttgtaccctctagttggaacg
atgagtacgatgccaggacttccaacccgcccagccatttttgatattgatttgaacttg
gaaacaggcaacattgaaggcctgttctag

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