KEGG   Dipodomys ordii (Ord's kangaroo rat): 105984857
Entry
105984857         CDS       T07834                                 
Symbol
Mthfd1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
dord  Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00670  One carbon pool by folate
dord01100  Metabolic pathways
dord01240  Biosynthesis of cofactors
dord04981  Folate transport and metabolism
Module
dord_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:dord00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    105984857 (Mthfd1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    105984857 (Mthfd1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dord04147]
    105984857 (Mthfd1)
Enzymes [BR:dord01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     105984857 (Mthfd1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     105984857 (Mthfd1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     105984857 (Mthfd1)
Exosome [BR:dord04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   105984857 (Mthfd1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 105984857
NCBI-ProteinID: XP_012870629
Ensembl: ENSDORG00000015181
UniProt: A0A1S3F3E6
LinkDB
Position
Unknown
AA seq 935 aa
MAPAEVLSGKVVSAQIRERLKNQVTQMKEQVPGFIPSLAILQVGNRDDSNLYINAKLKAA
EEVGIKATHIKLPRTATESEVLKQITFLNEDSTVHGFIVQLPLDSENPINTELVINAVAP
EKDVDGLTSISAGKLARGDLNDCFIPCTPKGCLELIKKTGVQIAGRHAVVVGRSKIVGAP
MHDLLLWNNATVTTCHSKTANLGEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINY
VPDNTKSSGKKVVGDVAYEEAKERASFITPVPGGVGPMTVAMLMQSTVESAQRFLEKFKP
GKWAIQYNSLNLKTPVPSDIDISRSCKPKPIGNLAREIGLLSEEVELYGETKAKVLLSAL
ERLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGI
KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARMFHELTQTDKALFNRLV
PSVNGVRKFSDIQIRRLQRLGIEKTDPTTLTDEEINKFARLDIDPETITWQRVLDTNDRF
LRKITIGQAPTEKGYTRTAQFDISVASEIMAVLALTSSLEDMRERLGKMVVASSKKGEPI
TTEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVG
PEGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPTVTAGLPLP
KAYTEENLELVEKGFSNLRKQIENARMFGVPVVVAINAFKTDTEAELGLISRLAREHGAF
DAVKCTHWAEGGKGAVALAQAVQRAAQAPSNFQLLYDLQLPVEDKIRIIAQKIYGADDIE
LLPEAQHKVEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFVLPIRDIRASVGAGFL
YPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcgccggcggaagtcctgagcgggaaggtggtctctgcgcaaataagggagagacta
aagaaccaagtcactcagatgaaggagcaagttccaggctttatacccagcctggcaatt
ttgcaggttggcaacagagatgattccaatctttatataaatgcgaagttgaaggctgct
gaagaggttgggatcaaagccactcacattaagttgccaagaacggccacagaatctgag
gtgttgaagcagatcacattcttgaatgaagactccacagtgcatggattcatagtgcag
ctgcctttagattctgagaatcccattaacactgaattggtcatcaatgctgttgcacct
gaaaaggatgtggacgggttgacaagtatcagtgctggcaaacttgctagaggtgatcta
aatgactgtttcattccttgtacacctaaaggatgcttggaactaatcaagaagacaggg
gtgcagattgctggaaggcatgctgtggtggtcgggcgcagtaaaatagttggtgccccc
atgcatgacttgctcctgtggaataatgctacggtgaccacctgccactcaaagactgcc
aatctcggtgaagaggtaaacaaaggtgatatcctggtggtggcaactggccagcctgaa
atggtaaaaggggaatggatcaaacctggagcaatcgtcatcgactgtggaatcaattat
gtcccagataatacaaaatcaagtggaaagaaagttgtgggcgatgtggcgtatgaggag
gccaaagagagggcaagcttcatcacgcctgtccctggtggtgtggggcccatgacggtg
gccatgctgatgcagagcacagtcgagagtgcacagcgtttcctggagaaatttaaaccc
ggaaaatgggcaatccagtataacagccttaacctgaagacacctgttccaagtgacatt
gatatatcacgttcttgcaaaccaaagcccattggtaacttggctcgagaaattggcctg
ctctcagaagaggtagaattatatggtgaaacgaaggccaaagttctgctgtccgcactg
gagcgcctgaagcaccagcccgatgggaaatatgtggtggtgacgggaataactccaaca
cccctgggagaaggaaaaagcacgaccaccatcgggctggtgcaagccctcggggcccac
ctctatcagaatgtcttcgcctgtgtgcgacagccttctcaaggcccaacctttggaata
aaaggcggcgctgcaggaggtggctattcccaggtcattcctatggaagagtttaatctc
cacctcactggtgacatccacgccatcactgccgctaacaacctcgttgctgcagccatt
gatgctcgaatgttccatgaactgactcagacagacaaggctctctttaatcgtttggtg
ccatcagtaaatggagtgagaaagttctctgatatccagattcgaagattacagagacta
ggcattgagaagacagatcctaccacgttgacagatgaagagataaacaaatttgcaaga
ttggatattgacccagaaaccataacttggcaaagagtgttggataccaatgatagattc
ctgaggaagatcaccattggacaggctccaacagagaaaggatacacacggacggcccag
tttgatatctctgtggccagtgaaattatggctgtcctggctctcactagctctctggaa
gacatgagagagagactgggcaaaatggttgtggcatccagtaagaaaggggaacccatc
actactgaagatctgggagtgagcggcgcactgaccgtgctgatgaaggatgcaatcaag
cccaatctcatgcagacattagagggcactccagtgttcgttcatgcgggaccctttgcc
aacatcgcgcatggcaattcttcaatcattgcagaccggatcgcactcaaacttgttggc
ccagaaggctttgtagtgactgaagcagggtttggagcagacattggaatggaaaagttc
tttaacatcaaatgccgctactctggactccgccctcacgttgtggtgctcgttgccact
gtcagggctcttaagatgcatggcggaggccccacggtcactgctggactgcctcttccc
aaggcttacacagaggagaacctggagctggttgaaaaaggcttcagtaacttgaggaaa
caaatagaaaatgccagaatgtttggagttcctgtggtagtggccataaatgcattcaag
actgataccgaggctgagctgggcctcatcagccgcctcgccagagagcatggggcattt
gatgcagtcaagtgcactcactgggcagaagggggaaagggggctgttgccctggctcag
gctgtccagagagcagctcaggcgcccagcaacttccaactcctctatgaccttcagctc
ccagttgaggataaaatcaggatcattgcacagaagatctatggggcagatgacattgag
ttgctccctgaagctcagcacaaagttgaagtctacacaaagcagggctttggtaatctg
cccatctgcatggccaaaacacacttgtccttgtcccacaacccagagcaaaaaggtgta
cctacgggcttcgttctgcccatccgggacatccgtgccagtgtcggggctggtttcctg
taccctttagtgggaacgatgagcacaatgcctggccttcctactcggccctgtttttat
gatattgacttggaccctgagactgaacaggtgaatggactgttctaa

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