KEGG   Cuculus canorus (common cuckoo): 104062339
Entry
104062339         CDS       T08597                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cuca  Cuculus canorus (common cuckoo)
Pathway
cuca00670  One carbon pool by folate
cuca01100  Metabolic pathways
cuca01240  Biosynthesis of cofactors
cuca04981  Folate transport and metabolism
Module
cuca_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cuca00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    104062339 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    104062339 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cuca04147]
    104062339 (MTHFD1)
Enzymes [BR:cuca01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     104062339 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     104062339 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     104062339 (MTHFD1)
Exosome [BR:cuca04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   104062339 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall DUF6507
Other DBs
NCBI-GeneID: 104062339
NCBI-ProteinID: XP_009562677
LinkDB
Position
5:complement(7520903..7564261)
AA seq 972 aa
MRGGAGGARNLGGTWGGASRILPASAAATGSRLPALAMAPAEILSGKIVSAQVRERLKKQ
VVEMTEKFPGFRPGLAILQVGNRDDSNLYINMKLKAAAEIGISANHIKLPNTATEADVLK
CIASLNGDPAVHGFIVQLPLDSDKPINTEKITNAVAPEKDVDGLSSINAGKLSRGDLGDC
FIPCTPKGCMELIRQTGVQVAGKRAVVIGRSKIVGAPMHDLLLWNNATVTTCHSKTSTLA
EEVGKADILVVAAGKAEMVKGEWIKPGAIVIDCGINHVPDSTKPSGKRVVGDVAYSTAKE
KASYITPVPGGVGPMTVAMLMQSTVESAQRFLEKFQPGKWNIQYNHLTLKIPVPSDIEIS
QSCIPKPIDQIAREIGLLPDEVELYGQTKAKVHLSTLKRLKNQPDGKYVVVTGITPTPLG
EGKSTTTVGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYCQVVPMEEFNLHLT
GDIHAITAANNLVAAAVDARIFHELTQTDQALYSRLVPSVNGVRKFSNIQIRRLQKLGIN
KTDPTALTKEEVNLFVRLDIDPGTITWQRVLDTNDRFLRKITIGQSPTEKGFSRTAQFDI
TVSSEIMAVLALSDGLDDMKKRLGRMVVASSKRGEPVTADDLGVTGALAVLMKDAVKPNL
MQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGKEGFVVTEAGFGADIGMEKFFNI
KCRYSGLRPHVVVLVATVRALKMHGGGPAVTAGVPLPKEYMEENLQLLAKGCSNLNKQIQ
NARMFGVPVVVAVNAFKTDTKAELALVVQLAKEAGAFDAVECTHWAEGGKGAVALARAVQ
RASQAPSNFRFLYNVELPVVDKIRLIARQIYGASDIELLPEAQEKVALYTKQGFGNLPIC
MAKTHLSLSHDPEQKGAPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDID
LDPVSGEVNGLF
NT seq 2919 nt   +upstreamnt  +downstreamnt
atgcgcggcggggccggcggcgcccgaaacttgggtggcacgtgggggggcgcgtcccgc
attctccccgcgagcgccgccgcgaccggcagccgccttcccgccctcgccatggccccc
gccgagatcctcagcggcaagatagtctccgcacaagtgagagagagactaaagaagcaa
gttgttgagatgacagagaaatttccaggcttcagaccaggactcgcaattttgcaggtt
ggaaatcgggatgattcaaacctctacattaatatgaagctgaaggcggctgctgagatt
gggatcagtgccaatcacataaaactgccaaacacagcaacagaagctgatgtcctcaaa
tgcatcgcgtctttgaatggagaccctgctgttcatggctttatagtgcagctgccactt
gactctgataaacctatcaacacagaaaaaataaccaatgctgttgcacctgagaaggat
gtagatggcttaagtagcatcaatgctgggaaactctctagaggggaccttggagactgc
tttattccctgtacaccaaaaggatgcatggaacttatcaggcagacaggcgtccaagtt
gcagggaaaagagctgtagtgattggtcgcagtaagattgttggtgctcccatgcatgac
ctgctgctctggaataatgcaacggtaaccacttgtcattcaaagacatcgacactggct
gaggaggttggtaaagctgatatcctggtggttgcagctggtaaagctgaaatggtaaaa
ggtgaatggatcaaacctggtgcaatcgtaatagactgtggaattaatcatgtgccagac
agcacaaagcccagtggaaaacgagttgtaggagatgtggcgtacagcacagcaaaggaa
aaagcttcctacatcaccccagttcctggtggcgttgggcctatgactgtggccatgtta
atgcagagcacagtggagagcgcacagcgttttctagagaagttccagcctgggaaatgg
aacatccaatataaccatcttaccctgaagatacctgttccaagtgatattgaaatatca
cagtcttgcataccaaagcccattgatcaaattgcaagagaaattggcctgctccctgat
gaggtggaactgtacggccaaaccaaagccaaagttcatctgtcaactctgaaacgtctg
aagaaccagccagatggcaaatacgttgttgttactgggataactcctactcccctggga
gaagggaaaagcactaccactgttggtcttgttcaagccttaggagctcaccttcatcag
aatgtctttgcctgtgttcggcagccttctcaggggccaacctttggtataaaaggtgga
gctgcaggtggtggctattgtcaagttgtccccatggaagagtttaaccttcacctcacc
ggtgacattcatgctatcactgcagccaacaacctggtcgctgctgccgttgatgcacgt
atattccatgagctaactcagactgaccaggctctctacagccgcttggtgccttctgtc
aatggtgttaggaaattctcaaacattcagatccgaagactgcagaaattgggcattaat
aaaaccgatcctacagctttgacaaaggaagaagtaaacttatttgtgagactggacatt
gacccaggcaccataacatggcaaagagtactcgatacaaatgacaggttccttaggaag
atcactattggacagtctccaacagaaaaaggcttctcacgaacggctcagtttgacatc
acggtgagcagtgaaatcatggcagttctagcgctctctgatggattagatgatatgaaa
aagcgactcggcagaatggtagtagcttccagcaagagaggagagccagttacagcagat
gaccttggagtgactggtgcattggcggtcttgatgaaagatgctgttaaaccaaacctc
atgcagacactagaaggaacaccagtgtttgttcatgctggaccttttgccaatattgca
catgggaattcttcagtgttggcagacaaaatagcacttaagcttgtgggtaaagaggga
tttgttgttacagaagcaggatttggtgcagatataggcatggagaaattctttaatatt
aagtgccgctattctggtctccgtcctcatgtggtggtgttggttgctactgtccgagct
ctgaaaatgcatggaggagggcctgcagtcactgctggggtacctttgccgaaggagtac
atggaggagaatcttcagctgttagcaaaaggctgcagtaacctaaacaagcaaatccaa
aatgcacggatgtttggtgtcccagttgtagtggctgtcaatgctttcaaaacagataca
aaggctgagctggcccttgttgtacagctggcaaaggaagcgggagcgtttgatgctgtg
gagtgcactcactgggcagaaggaggtaaaggagcagttgcactggcccgagctgttcag
agagcatcacaggcacccagcaacttccggttcctctataatgtggagctccctgttgta
gataagatcaggcttattgcacggcagatctatggggcaagtgacattgagctccttcca
gaagcccaggagaaagttgccttgtacactaagcaaggatttggaaacctgccaatctgc
atggctaaaactcacttatcattatctcatgaccctgaacaaaaaggagcgcctacaggt
tttattctgccaatccgagacattcgagccagtgttggtgctggattcctgtatccacta
gtaggaacgatgagcactatgccaggacttcctacaagaccctgtttctatgatatagac
ttggacccagtgtcaggagaagtcaatgggctcttttga

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