KEGG   Thermochaetoides thermophila: CTHT_0045900
Entry
CTHT_0045900      CDS       T03100                                 
Name
(RefSeq) C-1-tetrahydrofolate synthase-like protein
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cthr  Thermochaetoides thermophila
Pathway
cthr00670  One carbon pool by folate
cthr01100  Metabolic pathways
cthr01240  Biosynthesis of cofactors
cthr04981  Folate transport and metabolism
Module
cthr_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cthr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CTHT_0045900
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CTHT_0045900
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cthr04147]
    CTHT_0045900
Enzymes [BR:cthr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     CTHT_0045900
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     CTHT_0045900
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     CTHT_0045900
Exosome [BR:cthr04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   CTHT_0045900
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 18258628
NCBI-ProteinID: XP_006694970
UniProt: G0S9H4
LinkDB
Position
Unknown
AA seq 1074 aa
MKRQLLLQLSRVRSTNCRSVVIIERRQWYHEDSEKTTITDSVADLKTGTVEDKTRGLPDF
RRPSSADIGRSAAPRSTGSFLELAPRQRTSPPLPNPIPIPPALNNKRRCALLRPQFPRQP
SIAPSRAFSSSVAAMAAAKIDGTAIARKVREQLKAEIAARKAANPRFNPCLKIIQVGDRS
DSTTYVRMKLKASEEVGIAAELIKFDESATEAELIARVTALNNDPSVHGILVQLPLPKHV
SEYNVTSAVASEKDVDGFGTHNIGELAKRGGRPFFVPCTPKGIMVLLKESGVELAGKNAV
VVGRSDIVGSPVSYLLKNADATVTVCHSKTKDLAEHLKQADVVVVAIGQPGFIKGEQLKP
GCVVIDVGTNYIPDATKKSGQRLVGDVDFESASQVASQITPVPGGVGPMTVAMLLQNVLD
AANQAYEAERKRHITPLPLHLQTPVPSDIAISRAQRPKPITQIAKEIGIAASELEPYGSY
KAKVDLSILKRLAHRRDGRYVVVTGITPTPLGEGKSTTTMGLAQALGAHLGRVTFANVRQ
PSQGPTFGIKGGAAGGGYSQVIPMDEFNMHLTGDIHAITAANNLLAAAIDTRMFHEATQK
DGPLYRRLVPVKNGKRSFTPVMLRRLKKLGIDKTDPDSLTEEEIRRFARLDIDPETITWR
RVLDVNDRHLRGVTIGTAPTEKGHARQTGFDISVASECMAILALSTSLADMRERLGRMVV
ASSKSGEPITCDDIGCGGALAALMKDAIKPNLMQSLEGTPVFVHAGPFANISIGNSSILA
DKMALKLAGTEPDEDHSAKAGFVVTEAGFDFTMGGERFFNIKCRTSGLVPDVVVVVATIR
ALKVHGGGPPISPGAPLDPVYKEENVEVLRKGCVNLAKHIANARSYGVPVVVAINKFATD
TEAEVAVVREEAIKAGAEDAILANHWAEGGKGAVDLAKAVVAAAEKPKNFKLLYSLENNT
IRDRIETIAREMYGASGVEFSELAQKKIDLYTNQGFGNLPICIAKTQYSLSHDPELKGAP
TGFIVPIRDVRMAAGAGYLYALAADIQTIPGLPTAPGYLNVDVDAETGEIQGLF
NT seq 3225 nt   +upstreamnt  +downstreamnt
atgaagcgccaattgctattgcagctgagcagagtgagatcaacaaactgcagatcggtg
gtaatcattgagagacgacaatggtaccacgaagacagcgagaaaaccaccatcacagac
tctgtcgcagatttaaagacaggcactgtcgaggacaaaacaaggggcctgcccgacttt
cggcggccttcctcggctgacatcggacgctccgcagccccgcgttccactgggagtttc
ctggagcttgcaccccgccaaagaacttcaccaccactccccaaccccatccccattcct
cctgccctcaacaacaagcgacgctgcgcacttttgcgtccccaattcccccgccagcct
tcgattgcccccagcagggcgtttagcagctcggtagcagccatggccgccgcaaagatc
gacggaaccgcaattgcccgcaaggtgcgcgagcagctcaaggctgaaattgccgcccgc
aaagctgcaaatccgcgcttcaacccctgcctcaagatcatccaggtcggcgaccgctcc
gactcgaccacctatgtgcgcatgaagctcaaggcctccgaggaggtcggcatcgctgct
gagctgatcaagttcgacgagtctgccaccgaggccgagctgatcgcccgcgtgactgcg
cttaacaacgacccctccgtccacggcatcctcgtccagctgccgctgcccaagcatgtg
tccgaatacaatgtcacgtccgccgtcgccagcgagaaggatgtcgatggcttcggcacc
cacaacattggcgagctggccaagcgcggcggccgccccttcttcgtgccctgcaccccc
aagggtatcatggtgctgctgaaggaatctggtgtcgagctggctggcaagaacgccgtt
gtggttggccgcagtgatatcgtcggcagccctgtcagctacctgctgaagaatgccgac
gccacggtgactgtctgccactccaagaccaaggacctggcggagcacctcaagcaggcc
gacgtcgtggttgttgccattggccagcccggcttcatcaagggcgagcagctcaaacct
ggctgtgtcgtcattgatgtcggcaccaactacatccccgatgcgactaagaagtcgggc
cagcgcctggttggcgatgtcgacttcgagtcggcttcccaggttgcttcccagattacg
cctgtgcctggcggcgtcggacccatgactgtcgccatgctgctgcagaacgtcttggac
gccgctaaccaggcctatgaggctgaacgcaagaggcacatcacccctcttcccctccac
ctccagacccccgtcccctcggacattgccatttcgcgcgcccagcgccccaagcccatc
acccaaatcgccaaggagatcggcattgccgcctctgagctcgagccatatggctcttat
aaagccaaggttgacctgagcatcctcaagcgcctggctcatcgccgtgatggccgctac
gtcgtcgtcactggcattacccctactcccctgggtgagggcaagtctacgacgaccatg
ggtctggcccaggctctgggtgctcacctcggccgtgttacctttgccaatgtgcgtcag
cccagccagggcccgaccttcggcatcaagggtggtgctgctggaggcggttacagccaa
gtcatccccatggacgagttcaacatgcacttgacgggtgatatccacgctattactgcg
gccaacaaccttctggctgctgcgattgatacccgtatgttccacgaggccactcagaag
gacggtcctctctaccgccgtctggttccggtcaagaacggcaagcgttctttcactccc
gtgatgcttcgccgtctcaagaagctcggcatcgacaagaccgatcccgactccctgacc
gaggaggaaatccggcgctttgcccgcctggacatcgaccccgaaaccatcacctggcgt
cgcgtactcgacgtcaacgaccggcacctgcgcggcgtgaccatcggcaccgcccccacc
gagaagggccacgcccgccagacgggcttcgacatctctgttgccagcgagtgcatggcc
atcctggctctcagcaccagcctggccgacatgcgtgagcgcctgggccgcatggtcgtc
gccagctccaaatccggggagcccatcacctgcgacgacatcggctgcggcggtgccctg
gccgccctcatgaaggacgccatcaagcccaacctgatgcagtccctggagggcacgccc
gtcttcgttcacgcaggcccattcgccaacatctccatcggcaacagctccattcttgct
gacaagatggctctcaagttagccggcactgagcccgacgaagaccattccgccaaggca
ggcttcgtcgtcacagaagccggcttcgacttcaccatgggtggcgagcgcttcttcaac
attaagtgccgcacctcaggcctggtcccggacgtcgttgtcgtcgtcgccaccatccgc
gcgctcaaggtccacggtggcgggcccccgatctcccccggtgccccgctcgacccggtt
tacaaggaggagaacgtcgaggtcctccgcaagggctgcgtcaacctcgccaagcacatc
gccaatgccaggtcgtacggcgtgcccgtcgtcgtggccatcaacaagtttgccaccgac
accgaagccgaggttgccgtggtccgcgaggaagccatcaaagccggcgcggaagacgcc
atcctggcgaaccactgggccgagggcggcaagggcgccgtcgacctcgccaaggcggtc
gtggccgccgcggagaagcccaagaatttcaagctcctgtactccctcgagaacaacacc
attcgcgaccgcatcgaaaccatcgcgcgcgaaatgtacggcgcctcgggcgtcgaattc
tccgagctggcgcagaagaagatcgatctgtacaccaatcagggctttggcaacctgcca
atctgcattgccaagacgcaatatagtctgagccacgaccccgaactgaagggcgcgcca
acgggattcatcgtgcccattcgcgatgtgagaatggcagctggcgccgggtatttgtat
gcccttgccgcggacatacaaacgattcctggcttgccgaccgcgccggggtatttgaat
gtggatgttgatgctgagacgggggagattcaggggctgttctaa

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