KEGG   Chaetura pelagica (chimney swift): 104391399
Entry
104391399         CDS       T08631                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cpea  Chaetura pelagica (chimney swift)
Pathway
cpea00670  One carbon pool by folate
cpea01100  Metabolic pathways
cpea01240  Biosynthesis of cofactors
cpea04981  Folate transport and metabolism
Module
cpea_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cpea00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    104391399 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    104391399 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cpea04147]
    104391399 (MTHFD1)
Enzymes [BR:cpea01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     104391399 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     104391399 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     104391399 (MTHFD1)
Exosome [BR:cpea04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   104391399 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH DUF6507 OCD_Mu_crystall
Other DBs
NCBI-GeneID: 104391399
NCBI-ProteinID: XP_009998971
LinkDB
Position
Unknown
AA seq 909 aa
MKEKYPGFTPGLAILQVGNRDDSNLYINMKLKAAAEIGISANHIKLPNTATEADVLKCIA
SLNGDPAVHGFIVQLPLDSDKPINTEKITNAVAPEKDVDGLSSINAGKLSRGDLGDCFIP
CTPKGCMELIRQTGVQVAGKRAVVVGRSKIVGAPMHDLLLWNHATVTTCHSKTSTLAEEV
GKADILVVAAGKAEMVKGEWIKPGAIVIDCGINHVPDSTKASGKRVVGDVAYSTAKEKAS
YITPVPGGVGPMTVAMLMQSTVESAQRFLEKFQPGKWNIQYNQLTLKVPVPSDIEISQSC
IPKPIEQLAREIGLLPDELELYGQTKAKVHLAALKRLKNQPDGKYVVVTGITPTPLGEGK
STTTIGLVQSLGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYCQVVPMDEFNLHLTGDI
HAITAANNLVAAAIDARMFHEQTQTDQALYNRLVPSVSGVRKFSDIQIRRLQKLGINKTD
PMALTKEEINLFARLDIDPSTITWQRVLDTNDRFLRKITIGQAPTEKGFSRTAQFDITVS
SEIMAVLALSDGLDDMKKRLGRMVVASSKRGEPVTTDDLGVTGALAVLMKDAIKPNLMQT
LEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGKEGFVVTEAGFGADIGMEKFFNIKCR
YSGLRPHVVVLVATVRALKMHGGGPAVTAGVPLPKEYMEENLQLLAKGCSNLNKQIQNAR
IFGVPVVVAVNAFKTDTKAELALVVQLAKEAGAFDAVECTHWAEGGKGALALARAVQRAS
QAPSNFRFLYNVELPVIDKIRLIAQQIYGASDIELLPEAQEKVALYTKQGFGNLPICMAK
THLSLSHDPEKKGAPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDP
VSGEVNGLF
NT seq 2730 nt   +upstreamnt  +downstreamnt
atgaaagagaaatatccaggcttcacaccaggacttgcaattttgcaggttggaaatcgg
gatgattcgaacctctacattaatatgaagctgaaggctgctgctgagattgggatcagt
gccaatcacatcaaactgccaaacacagcaacagaagctgacgtcctcaagtgcattgcc
tctttgaatggagaccctgcagttcatggctttatagtgcagctgccacttgactctgat
aaacccatcaatacagaaaaaataaccaatgctgttgcacctgagaaggatgtagatggc
ttaagtagcatcaatgctgggaagctctctagaggggacctcggcgactgctttattccc
tgtacaccaaaaggatgtatggaacttatcaggcagacaggtgtccaggttgcagggaaa
agagctgtagtggttggtcgcagtaagattgttggtgctcccatgcatgacctgctgctc
tggaatcacgcaacggtgaccacttgccattcaaagacctcaacattggctgaggaggtt
ggtaaagctgatatcctggtggttgcagctggcaaagctgaaatggtaaaaggtgaatgg
atcaaacctggtgcgatcgtaatagactgtggaattaaccatgtgccagacagcacaaag
gccagtggaaaaagagttgtaggagatgtggcatacagtacagcaaaggaaaaagcttcc
tacatcacccctgttcctggtggtgttgggcctatgactgtggccatgttgatgcagagc
acagtggagagtgcacagcgttttctggagaagttccagcctggaaaatggaacatccag
tataaccagcttaccctaaaggtgcctgttccaagtgatattgaaatatcacagtcttgc
atacccaagcccattgagcaacttgcaagagaaattggcctgctccctgatgagctggag
ctctatggccaaactaaagccaaggtgcatctggcagctctgaaacgcctgaagaaccaa
ccagatggcaaatacgttgttgttactgggataactcctactcccctgggagaggggaag
agcaccaccactattggtcttgttcaatcgttaggagctcatcttcaccagaatgtcttt
gcttgtgttcggcagccttctcaggggccaacttttggtataaaaggtggagctgcaggt
ggtggctattgtcaagttgtccccatggatgagtttaaccttcacctcactggtgacatc
catgctatcactgcagccaacaacctggtcgctgctgctatcgacgcacgtatgttccat
gagcaaactcagactgaccaggctctctacaaccgtttggtgccttctgtcagtggcgtt
aggaagttctcggacattcagatccgaaggctacagaaattgggcattaacaaaactgat
cctatggctttgacaaaggaagaaataaacttatttgcgagattggacattgacccaagc
accataacatggcaaagagtgctggatacaaacgacaggttcctcaggaaaatcactatt
ggacaggctccaacagaaaaaggcttctcacgaacggctcagtttgacatcactgtgagc
agtgaaatcatggcagttctagcactctctgatgggttggatgatatgaaaaagcgacta
ggcagaatggtagtggcttccagcaagagaggagaaccagttacaacagatgaccttgga
gtgactggtgctctggctgtcttaatgaaagatgctataaaaccaaacctcatgcagaca
ctagagggaacaccggtgtttgttcatgctggaccttttgccaatattgcacatgggaat
tcttcagtgttggcagataaaatagcactgaagcttgtgggtaaagagggctttgttgtt
acagaagcaggatttggtgcagacataggcatggaaaaattcttcaatattaagtgccgc
tattctggtctccggcctcacgtggtggtgttggttgctactgtccgagctctgaaaatg
catggaggaggccctgcagtcactgctggggtacctttgccaaaagagtacatggaagag
aatcttcagctgttggcaaaaggctgtagtaacctaaacaagcaaatccaaaatgcacgg
atatttggtgtgccagtagtagtggctgtcaatgctttcaagacagatacaaaggctgag
ctggcccttgtagtacaactggcaaaggaagcaggggcttttgatgctgtggaatgcacc
cactgggcagagggaggtaaaggagcacttgctctggcccgagctgttcagagagcatca
caggcacccagcaacttcaggttcctctacaatgtggagctccctgttatagataagatc
aggctcattgcacagcagatctacggggcaagtgacattgagctacttccagaagcacag
gagaaggttgcgttgtacactaagcagggatttggaaacctgccaatctgcatggctaaa
actcacttgtcattgtctcatgaccccgagaaaaaaggagcccccacaggttttgttctg
cccatccgtgacattcgggccagtgttggtgctgggttcctgtacccactagtgggaacg
atgagcactatgccaggacttcctacaagaccctgtttctacgatatagacttggaccca
gtgtcaggagaagtcaatgggctcttttga

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