Brucella melitensis M28: BM28_B0497
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Entry
BM28_B0497 CDS
T01852
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bmz
Brucella melitensis M28
Pathway
bmz00280
Valine, leucine and isoleucine degradation
bmz00640
Propanoate metabolism
bmz00785
Lipoic acid metabolism
bmz01100
Metabolic pathways
bmz01110
Biosynthesis of secondary metabolites
bmz01210
2-Oxocarboxylic acid metabolism
Module
bmz_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bmz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BM28_B0497
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BM28_B0497
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BM28_B0497
Enzymes [BR:
bmz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BM28_B0497
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ADZ67746
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Position
2:481943..483295
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AA seq
450 aa
AA seq
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MGNLAEMAAKVCCAGTVVILRLPPIISHSTIHASFARCARMSDDVVLSLHVPEPEWRPGD
APDFSHVKIPRAGSVRRPEIDEKPEAMRDMAFSIIRVLNREGEAVGPWAGTLTDEELKDG
LRHMMMLRAYDARMMMAQRQGKTSFYMQHLGEEAVSCAFRKALRKGDMNFPTYRQAGLLI
ADDYPLVTMMNQIFSNEQDPLKGRQLPVMYSSKEHGFFTISGNLATQYTQAVGWAMASAI
SHDTKIAAAWIGDGSTAESDFHAALVFASTYKAPVVMNIVNNQWAISTFQGIARGGSGTF
AARGHGFGIPSLRVDGNDYLAVHAVAKWAVERARRNLGPTIVEYVTYRAGGHSTSDDPSA
YRPKAENDAWPLGDPILRLKNHLIKRGVWSEERHKQAEAEVMDIVVSAQREAEAIGKLHD
GRKPSMRDMFEDVYAETPPHLIRQRQEAGF
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
gtgggaaaccttgccgaaatggctgcaaaggtttgctgtgcaggcacggtcgtgattttg
cgtttgccgcctataatctctcattcgactatccatgccagttttgcgaggtgtgcccgc
atgagcgatgatgtcgtactttcactgcatgttcccgagccggaatggcgcccgggtgat
gcgccggatttctcccacgtcaagattccccgtgcaggcagcgtgcgcaggcccgaaatc
gatgaaaagccggaagccatgcgcgatatggcgttcagcatcatccgcgtgctgaaccgg
gaaggtgaggcggttggcccatgggcgggcacgcttaccgacgaggaactgaaggacggg
cttcgtcacatgatgatgttgcgtgcctatgatgcgcgcatgatgatggcgcaacgtcag
ggcaaaacctcgttctacatgcagcatctgggtgaagaggcggtgagttgcgccttccgc
aaggcgctgcgcaagggcgacatgaatttcccgacctaccgccaggcgggccttctcatc
gcggacgactatcccctcgtcacgatgatgaaccagatattctccaacgagcaggacccg
ctgaaaggccgccagcttccggtgatgtattcctcgaaagagcatggctttttcaccatt
tccggcaatctggcgacgcaatatacgcaggccgtcggctgggcgatggcatcggccatc
agccacgacacgaagattgccgccgcatggatcggtgacggctcgacggcggaaagcgat
ttccacgccgcactggtcttcgcctcgacctacaaggccccggtggtgatgaacatcgtc
aacaaccaatgggctatttccacctttcagggcattgcgcgcggcggttccggcactttt
gcggcgcggggccacggcttcggcattccgtcgctgcgcgtcgatggcaatgactatctg
gccgtccatgcggtggcgaaatgggcggtcgaacgcgcgcggcgcaatctcggcccgacc
atcgtggaatatgtgacctatcgcgccggcgggcactccacttcggacgatccgtccgcc
tatcgccccaaggcggaaaatgacgcatggccgcttggcgatccgatcctgcggctcaag
aaccacctcattaagcgcggcgtgtggtcggaagagcgccacaagcaggcggaagccgag
gtgatggatattgtggtgagtgcgcagcgcgaggcggaagccatcggcaagctgcatgat
ggccgtaagccctccatgcgcgacatgttcgaggatgtctatgccgaaacgccgccgcat
cttatccgccagcgtcaggaggcggggttttga
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