KEGG   Arvicanthis niloticus (African grass rat): 117697507
Entry
117697507         CDS       T08817                                 
Symbol
Mthfd1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu00670  One carbon pool by folate
anu01100  Metabolic pathways
anu01240  Biosynthesis of cofactors
anu04981  Folate transport and metabolism
Module
anu_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:anu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    117697507 (Mthfd1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    117697507 (Mthfd1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:anu04147]
    117697507 (Mthfd1)
Enzymes [BR:anu01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     117697507 (Mthfd1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     117697507 (Mthfd1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     117697507 (Mthfd1)
Exosome [BR:anu04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   117697507 (Mthfd1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 117697507
NCBI-ProteinID: XP_034344549
LinkDB
Position
Unknown
AA seq 1002 aa
MSFHCQRVTTSFRFACAPSLLGARRRRTGCISPRGPCARALCCPERARSDCNLIFAGVHV
GGRLAKAMAPAGILNGKVVSAQIRERLKNQVTQMQEQVPGFTPGLAILQVGDRDDSNLYI
NVKLKAAEEIGIKATHIKLPRTSTESEVLKHVVSLNEDASVHGFIVQLPLDSESAISTEA
VINAIAPEKDVDGLTSVNAGKLSRGDLNDCFIPCTPKGCLELIRETGVQIAGRHAVVVGR
SKIVGAPMHDLLLWNNATVTTCHSKTANLDKEVNKGDILVVATGQPEMVKGEWIKPGAVV
IDCGINYVPDDSKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAQR
FLLKFKPGKWTIQYNKLSLETPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGDTKA
KVLLSALDRLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPS
QGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDK
ALFNRLVPSVNGVRRFSDIQVRRLRRLGIEKTDPTTLTDDEINKFARLDIDPETITWQRV
LDTNDRFLRKITIGQSPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVAS
SKKGEPISCEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADR
IALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLQPHVVVLVATVRALKMHGGGPTV
TAGLPLPKAYTEEDLDLVEKGFSNLRKQIENARMFGVPVVVAINAFKTDTDAELDLIGRL
SREHGAFDAVKCTHWAEGGQGALALAQAVQRASQAPSSFQLLYDLKLSVEDKIRVIAQKI
YGADDIELLPEAQNKAETYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRA
SVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF
NT seq 3009 nt   +upstreamnt  +downstreamnt
atgagcttccactgtcagcgggttacgacgtctttccggttcgcttgcgcaccttcgctg
ctgggagcgcgacgcaggcgcactggctgtatttccccaagaggtccctgcgcacgtgcg
ttgtgctgtccggagcgcgcgcggagcgactgtaacctgatttttgctggtgttcacgtg
ggtggcagattagcaaaggccatggcaccagcgggaatcctgaacggcaaagtggtctca
gcgcaaataagggagcgactgaagaaccaggttactcagatgcaggagcaggtacctggc
ttcacccctggcctggcgatcctgcaggttggcgacagagatgattccaatctttatata
aacgtgaaactgaaggctgctgaagagattgggatcaaagctactcacattaaattacca
agaacgtccacagagtccgaggtgttaaaacacgtcgtctctctgaatgaggatgcctct
gtgcacgggttcatagtacagctgcctttggattcagagagtgccatcagcactgaagcc
gtcatcaatgccattgcccccgagaaggatgtggacgggttgacgagcgtcaatgctggg
aagctttccagaggtgatctcaatgactgcttcattccgtgcacacccaaagggtgcttg
gaactcatcagagagacaggggtgcagattgccggaaggcacgccgtggtggtggggcga
agtaaaatagttggtgcacccatgcatgacctgcttctgtggaacaacgccacggtgacc
acctgtcactccaagactgccaatctggacaaggaggtgaataaaggagacattctggtg
gttgccacgggacagcctgagatggtgaagggggagtggatcaagcctggggctgtggtc
atagactgtgggatcaattatgttccagatgattcaaaaccaaatggaaggaaagtcgtg
ggtgacgtggcatatgatgaggccaaggagagggcaagctttatcacacctgtccctggt
ggcgtggggcccatgaccgtggcaatgctgatgcagagcacagtagagagcgcacagcgc
ttcctgctgaaatttaagccagggaagtggacaattcagtataacaagctgagcctggag
acacctgtcccaagtgacattgctatatcacgatcttgcaaaccaaagctcatcggtaac
ctggcccgagaaattgggctactcacagaagaggtggaattgtacggggacacaaaggcc
aaggtcttgctgtcagcattagatcgcctgaagcatcagccagatgggaaatacgtcgtg
gtgactggaattactccaacacccctgggagaagggaaaagtacaaccacaatcgggctg
gtgcaagccctcggcgcccacctgcatcagaatgtttttgcgtgtgtgcgacagccttca
cagggccccacctttgggataaaaggtggcgctgcaggaggcggctattcccaggtcatt
cctatggaagagtttaatctccacctcactggtgacatccacgccatcactgctgctaat
aacctcgtggctgctgccatcgatgctcggatatttcatgagctgacccagacagacaag
gctctctttaatcgtctggtaccttcagtaaatggagtaagaaggttctctgacatccaa
gtccgcaggctacggaggctcggcattgagaagactgaccccaccacactgacagatgat
gagataaacaaatttgcaagactggatattgatccagaaactataacgtggcagagagtg
ttggacaccaacgatagattcctgaggaagatcacaattggacagtctccaacagagaaa
ggccacacacgcacggcccagtttgatatctctgtggccagtgaaatcatggcagtccta
gcccttactacttctctggaagacatgagagaaagactgggcaaaatggtggtggcatcc
agtaagaaaggggagcccatcagctgtgaagacctgggtgtgagtggggcgctgacagtg
ctgatgaaggacgcaatcaagcccaatctcatgcagaccttagagggcacaccagtgttt
gtccatgctgggcctttcgccaacattgcacacgggaattcctccatcattgcagaccgg
attgcactcaagctggtgggccctgagggctttgtagtgacagaagcaggattcggagca
gacataggaatggaaaagttcttcaacatcaagtgccggtattctggtctccagccgcac
gtggtggttctggtggccactgtcagggctcttaagatgcacgggggtggccccacggtc
accgctggactgcctcttcccaaggcttacacagaagaggacctggacctggttgaaaag
ggcttcagtaacttgaggaaacaaatagaaaatgctagaatgtttggagtgcctgtcgtc
gtggccataaatgcattcaagacagatacagatgctgagctggacctcattggccgcctc
tccagagaacatggggcttttgatgctgtcaagtgcacccactgggcagaagggggccag
ggggccttagccctggctcaggctgtccagagagcttcacaggcccccagcagcttccag
ctcctctatgacctcaagctctcagttgaggataaaatcagggtcattgcacagaagatc
tacggggccgatgacatcgaattgctccccgaagcacagaacaaagcagaaacctacaca
aagcagggctttgggaatctacccatctgcatggccaaaacacacttgtctttgtctcac
aacccagagcaaaaaggggtgcctactggcttcattctgcccatccgggacatccgtgcc
agcgttggagctggtttcctgtaccctttagtaggaacgatgagcacaatgcctggactc
cctacgcggccctgtttttatgatattgatttggaccctgaaaccgaacaagtgaatgga
ttgttttaa

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