Ailuropoda melanoleuca (giant panda): 100480163
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Entry
100480163 CDS
T01329
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00020
Citrate cycle (TCA cycle)
aml00480
Glutathione metabolism
aml01100
Metabolic pathways
aml01200
Carbon metabolism
aml01210
2-Oxocarboxylic acid metabolism
aml01230
Biosynthesis of amino acids
aml04146
Peroxisome
aml05230
Central carbon metabolism in cancer
Module
aml_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aml_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100480163 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100480163 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100480163 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100480163 (IDH1)
Enzymes [BR:
aml01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
100480163 (IDH1)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Cadherin-like
Motif
Other DBs
NCBI-GeneID:
100480163
NCBI-ProteinID:
XP_002918143
Ensembl:
ENSAMEG00000015244
UniProt:
D2H8H7
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Position
2:complement(171879897..171898571)
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AA seq
414 aa
AA seq
DB search
MSQKIHGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTSSDGSKKMTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG
KTVEAEAAHGTVTRHYRMYQKGEETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE
EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtctcagaaaatccatggcgggtctgtggtagagatgcaaggagatgaaatgacacga
atcatttgggagttgattaaagaaaaactcatatttccgtatgtggaactggacctgcac
agctatgatttaggcatagagaatcgtgatgccaccaatgaccaggtcaccaaggatgct
gcagaagctataaagaagtacaacgttggtgtcaagtgtgctaccatcacccccgatgag
aagagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcactatccga
aatattctgggtggcaccgtcttcagggaagctattatctgcaaaaatatcccccgtctt
gtgagcggatgggtaaaacccatcatcataggtcgtcatgcttacggggatcaatacaga
gcaactgattttgttgttcctgggcctggtaaagttgagataacctacacgtcaagtgat
ggatccaaaaaaatgacctacctggtacataactttgaagagggcggtggtgtggccatg
gggatgtacaatcaagataagtcaatcgaagattttgcgcatagttctttccagatggct
ctgtctaagagttggcctttgtatttgagcaccaaaaacactattctgaagaaatatgat
ggacgttttaaagacatctttcaggaaatatatgacaagcagtacaaatcccaatttgaa
gcccaaaaaatctggtatgagcataggctcattgacgatatggtggcccaagctatgaaa
tccgaaggaggcttcatctgggcctgtaaaaactatgatggtgacgtgcagtcggactcc
gtggcccaaggttatggctctcttggcatgatgaccagcgtgctgatttgtccagacggc
aagacagtagaagcagaggctgctcacgggaccgtcacccgtcactaccgcatgtatcag
aaaggagaggagacgtccaccaatcccattgcttccatctttgcctggaccagagggtta
gcccacagggccaagcttgataacaataaagagctcagcttctttgccaaggctttggaa
gaagtctgtgttgagaccattgaggctggcttcatgaccaaggacttggctgcttgtatt
aaaggtttgcccaacgtgcaacgttctgactacttgaatacatttgagttcatggacaaa
ctcggagaaaacttgaatataaaactggctcaggccaaactttaa
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