KEGG   Athene cunicularia (burrowing owl): 113480420
Entry
113480420         CDS       T05777                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
acun  Athene cunicularia (burrowing owl)
Pathway
acun00670  One carbon pool by folate
acun01100  Metabolic pathways
acun01240  Biosynthesis of cofactors
acun04981  Folate transport and metabolism
Module
acun_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:acun00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    113480420 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    113480420 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:acun04147]
    113480420 (MTHFD1)
Enzymes [BR:acun01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     113480420 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     113480420 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     113480420 (MTHFD1)
Exosome [BR:acun04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   113480420 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH DUF6507 OCD_Mu_crystall
Other DBs
NCBI-GeneID: 113480420
NCBI-ProteinID: XP_026705018
LinkDB
Position
5
AA seq 958 aa
MTAGGESTPPTCLTEDREKLRPLEFSPLLTSTLVVFFFFLFRQVRERLKKQVVEMKEKFP
GFRPGLAILQVGNRDDSNLYINMKLKAAAEIGISANHIKLPNTATEADVLKCIASLNGDP
AVHGFIVQLPLDSDKPINTEKITNAVAPEKDVDGLSSINAGKLSRGDLGDCFIPCTPKGC
MELIRQTGIQVAGKRAVVVGRSKIVGAPMHDLLLWNHATVTTCHSKTSTLAEEVGKADIL
VVAAGKAEMVKGEWIKPGAIVIDCGINHVPDSTKASGKRVVGDVAYSTAKEKASYITPVP
GGVGPMTVAMLMQVRGQIETAGHLYICLWGMLLLTISTLPNDIEISQSCIPKPIDQVARE
VGLLPDEVELYGQTKAKVHLSALKRLKNQPDGKYVVVTGITPTPLGEGKSTTTVGLVQAL
GAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYCQITPMEEFNLHLTGDIHAITAANNLVA
AAVDARIFHELTQTDQALYNRLVPSVSGVRKFSDIQIRRLQKLGINKTDPMALTKEEVNL
FVRLDIDPGTITWQRVLDTNDRFLRKITIGQSPTEKGFSRMAQFDITVSSEIMAVLALSD
GLDDMKKRLGRMVVASSKRGEPVTTDDLGVTGALAVLMRDAVKPNLMQTLEGTPVFVHAG
PFANIAHGNSSVLADKIALKLVGKEGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVL
VATVRALKMHGGGPAVTAGVPLPKEYMEENLQLLARGCSNLNKQIQNARMFGVPVVVAVN
AFKTDTKAELALVVQMAKEAGAFDAVECTHWAEGGKGAVALAQAVQRASQAPSNFRFLYN
VELPVIDKIRLIAQQIYGASDIELLPEAQEKVTLYTKQGFGNLPICMAKTHLSLSHDPEQ
KGAPAGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPVSGEVNGLF
NT seq 2877 nt   +upstreamnt  +downstreamnt
atgactgctggaggtgaaagcacaccaccgacctgcctcacagaggacagagaaaaactt
agacccctggaattcagccccttgttaacttctaccttggttgtttttttttttttcctc
ttcagacaagtgagagagagactaaagaaacaagttgttgagatgaaagagaaatttcca
ggcttcagaccaggactcgcaattttgcaggttggaaatcgggatgactcgaacctctac
attaatatgaagctgaaggctgctgctgagattgggatcagtgccaatcacataaaactg
ccgaacacagcaacagaagctgacgtcctcaagtgcattgcctctttgaatggagaccct
gctgttcacggctttatagtgcagctgccacttgacagtgataaacccatcaatacagaa
aaaataaccaatgctgttgcacctgagaaggatgtagatggtttaagtagcatcaacgct
gggaaactctctagaggggaccttggagactgctttattccctgtacaccaaaaggatgc
atggaacttatcaggcagacaggcatccaggttgcagggaaaagagctgtagtagttggt
cgcagtaagattgttggtgctcccatgcacgacctgctgctctggaatcatgcaacggta
accacttgtcactcaaagacctcaactctggctgaggaggttggtaaagctgatatcctg
gtggttgcagctggtaaagctgaaatggtgaaaggtgaatggatcaaacctggtgcaatc
gtaatagactgtggaattaaccatgtgccagacagcacaaaggccagtggaaaaagagtt
gtaggagatgtggcatacagtacagcaaaggaaaaagcttcctacattaccccagttcct
ggtggcgttgggcctatgactgtggccatgttaatgcaggtacgtgggcagattgagact
gctggtcatctttacatttgcctttggggtatgttgctgctgaccatcagcacgctacca
aatgatatcgaaatatcgcagtcttgcatacccaagcccattgatcaagttgcaagagaa
gttggcctgctccctgatgaggtggagctctacggccaaactaaagccaaggttcatctg
tcagctctgaaacggctgaagaaccaaccagatggcaaatacgttgttgttactgggata
actcccactcccctgggagaggggaaaagcaccaccactgttggtcttgttcaagcctta
ggagcacaccttcaccagaatgtctttgcctgtgttcggcagccttctcagggaccaacc
tttggtataaaaggtggagctgcaggtggtggctattgtcaaattacccccatggaagag
tttaaccttcaccttactggtgacatccatgctatcactgcagccaacaacctggttgct
gctgctgtcgacgcacgtatattccatgagctaactcagactgaccaggctctctacaac
cgtttggtgccttctgtcagtggtgttaggaagttctcagacattcagatccgaagacta
cagaaattgggcattaacaaaactgatcctatggctttgacaaaggaagaagttaactta
tttgtgagattggacattgacccaggcaccataacatggcaaagagtactggacacaaat
gacaggttccttaggaaaatcactattggacagtctccaacagaaaaaggcttctcacga
atggctcagtttgacatcacggtgagcagtgaaatcatggcagttctagcactctctgat
gggttggatgatatgaaaaagcgactgggcagaatggtagtagcctccagcaagagagga
gagccagttacaacagacgaccttggagtgactggtgctctggctgtcctgatgagagat
gctgttaaaccaaacctcatgcagacactagagggaacaccagtgtttgtacatgctgga
ccttttgccaatattgcacatgggaattcttcagtgttggcagacaaaatagcactgaag
cttgtgggtaaagagggttttgttgttacagaagcaggatttggtgcagacataggcatg
gagaaattctttaatattaagtgccgctattccggtctccggcctcatgtggtggtgttg
gttgctactgtccgagctctgaaaatgcacggaggagggcctgcagtcactgctggggta
cctttaccaaaggagtacatggaagagaatcttcagctgttggcaagaggctgtagtaac
ctaaacaagcaaatccaaaacgcacggatgtttggtgtcccagtagtagtggctgtcaat
gctttcaaaacagatacaaaggctgaactggcccttgtagtccaaatggcaaaggaagcg
ggagcgttcgatgctgtggagtgcactcactgggcagagggaggtaaaggagcggttgca
ctggcccaggctgttcagagagcgtcgcaggcaccaagcaacttcaggttcctctataat
gtggagctccctgttatagataagatcaggcttattgcacagcagatctacggggcaagt
gacattgagctacttccagaagcacaggagaaagtcaccttgtacactaagcaaggattt
ggaaacctgccaatctgcatggctaaaactcacttatcgctgtctcatgaccctgaacaa
aaaggggcacctgcaggttttattctgccaatccgagacattcgggccagtgttggtgct
ggattcctgtatccactagtaggaacgatgagcactatgccaggacttccgacaagacct
tgtttctatgatatagacttggacccagtgtcaggagaagtaaatgggctcttttga

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