Actinoplanes sp. SE50: ACWT_0080
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Entry
ACWT_0080 CDS
T05392
Name
(GenBank) pyruvate dehydrogenase E1 subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
acts
Actinoplanes sp. SE50
Pathway
acts00280
Valine, leucine and isoleucine degradation
acts00640
Propanoate metabolism
acts00785
Lipoic acid metabolism
acts01100
Metabolic pathways
acts01110
Biosynthesis of secondary metabolites
acts01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
acts00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ACWT_0080
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ACWT_0080
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACWT_0080
Enzymes [BR:
acts01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
ACWT_0080
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ATO79495
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Position
complement(85258..86403)
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AA seq
381 aa
AA seq
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MAKGERKAGGGSDAPAGGFVQLLTPDGEHLGSVTTADGATYSVDFTDDEYRGLYRDLVTV
RRLDAEATALQRQGELGLWASLLGQEAAQVGSGRALRPQDMAFPTYREHGVLYCRGIDPI
MPFGLFRGVDQGGWDSNEHKFNSYTIVIGSQTLHATGYAMGVTMDGKTGSADGEAVIAYF
GDGATSQGEVNEAFVWSGVFNAPIVFFCQNNQYAISEPLERQTRIPLYRRAAGYGFPGIR
IDGNDVLATYAVTRAALDNARNGQGPTLIEAYTYRMGAHTSSDDPTRYRIASEVESWKAK
DPISRVAAFLAKQKLADDDFFAEVDATAGKLALDLRERVLAMPDPQPVTMFDNVYPTGSP
ELDRQRAAFTGYHASFEGSGH
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaaggcgaacgcaaagccggtggcggcagcgacgccccggcgggcggcttcgtc
cagctactcacgcccgacggcgagcacctcggcagcgtcaccacggcggacggcgccacc
tactcggtcgacttcaccgacgacgagtatcgcggcctctaccgcgacctggtgacggtc
cgccggctcgacgccgaggcgaccgccctgcagcggcagggcgagctcgggctctgggcc
agcctgctgggtcaggaggccgctcaggtcggctccggccgggcgctgcgcccgcaggac
atggcgttccccacctaccgcgagcacggcgtgctgtactgccgcgggatcgacccgatc
atgccgttcggcctgttccgcggcgtcgatcagggcggatgggactcgaacgagcacaag
ttcaacagctacaccatcgtgatcggctcgcagacgctgcacgcgaccggttacgccatg
ggcgtcaccatggacggcaagaccggcagcgccgacggcgaggccgtcatcgcgtacttc
ggcgacggcgcgaccagccagggcgaggtcaacgaggcgttcgtctggtccggggtgttc
aacgccccgatcgtcttcttctgccagaacaaccagtacgcgatctccgagccgctggag
cggcagacccgcatcccgctgtaccggcgcgccgccggctacggattcccgggcatccgg
atcgacggcaacgacgtgctggcgacgtacgcggtgaccagggccgcgctggacaacgcg
cgcaacggccagggcccgaccctgatcgaggcgtacacctaccggatgggcgcgcacacc
agctccgacgaccccacccgctaccggatcgcctccgaggtcgagtcgtggaaggcgaag
gatccgatctcccgggtcgccgcgttcctggccaagcagaaactggccgacgacgacttc
ttcgccgaggtcgacgccaccgccggcaaactcgccctggacctgcgggaacgggtgctg
gcgatgcctgatccacaaccggtcacgatgttcgacaacgtctatcccaccggctccccg
gagctcgaccggcagcgcgccgcgttcaccgggtaccacgcgtcgttcgaggggagtggg
cactga
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