Actinoplanes sp. NBRC 14428: Asp14428_58520
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Entry
Asp14428_58520 CDS
T08315
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
actr
Actinoplanes sp. NBRC 14428
Pathway
actr00020
Citrate cycle (TCA cycle)
actr00630
Glyoxylate and dicarboxylate metabolism
actr00785
Lipoic acid metabolism
actr01100
Metabolic pathways
actr01110
Biosynthesis of secondary metabolites
actr01120
Microbial metabolism in diverse environments
actr01200
Carbon metabolism
actr01210
2-Oxocarboxylic acid metabolism
Module
actr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
actr_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
actr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Asp14428_58520 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
Asp14428_58520 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Asp14428_58520 (kgd)
Enzymes [BR:
actr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Asp14428_58520 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Asp14428_58520 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Asp14428_58520 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Asp14428_58520 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
BCJ54377
LinkDB
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Position
complement(6255565..6258870)
Genome browser
AA seq
1101 aa
AA seq
DB search
MDASLEVPTATSVRAIPAKLLVDNRIVINNHLARGRGGKVSFTHLIGWALVRSVKAHPEM
NNSFAEVDGKPAVVQPEHINLGIAIDLAKKDGTRTLVVPSIKNCEQMDFRQFWQAYEDVV
RRARRNELTMDDYAGTTISLTNPGGIGTVHSIPRLMSGQSAIIGVGAMEYPAPYSGMSDE
TLTEHGVSKVTTLTSTYDHRVIQGAQSGEFLKAMHEFLLGEHSFYDDIFTSLRIPYEPVR
WVRDVARTSEGQIDKAARVVELIHAYRVRGHLMADTDPLEFEIRRHPDLDVLQHGLTLWD
LDRTFPVGGFAGKQKMKLRDVLGVLRDTYCRRVGIEYMHIQGPEERRWIQDRIEIKYTKP
DQEEQKHILNRLNAAEAFETFLQTKFVGQKRFSLEGGESLIPLLDAVLESSAEAGLDEMV
IGMAHRGRLNVLANIVGKPYEKIFNEFEGQMDPKSAHGSGDVKYHLGQTGKYTTPDGENS
TTVSVVANPSHLEAVDPVLEGIVRAKQDRLDLGLHGYTVLPVLVHGDAAFAGQGVVAETL
NLSQLRGYRTGGTVHVVVNNQVGFTTAPEYSRSSLYSTDVARMIQAPIFHVNGDDPEAVV
RVAKLAFEYRQAFNKDVVIDMVCYRRRGHNEGDDPSMTNPRMYQIIDTKRSVRKLYTEEL
IGRGDITIDGAQEQLRDYQSQLEKVFKATRDSAGSPPRVRPTPGDEPEPTVESAVDAAVV
KSVGQAHVDLPEGFTPHKRVQQLLERRARMSVEGGIDWGFGELVAFGSLLAQGVTVRLAG
QDSRRGTFTSRHASIVDAKTGDDFLPLSTLATGNARFFVHDSLLSEYAAMGFEYGYSVEN
PDALVLWEAQFGDFVNGAQSIVDEFISSGEVKWGQQSSLVLLLPHGQEGQGPDHSSGRPE
RFLQLCAQDNMRVANPTTPANYFHLLRRQALSTKRKPLIVFSPKSLLRHKLAVSSVADFT
TGSFQPVLGDAGINGKPLDASAVKRVLLCSGKVYYDLFQARAERGITDTAIIRMEQIYPL
PVEELKAVLHQFPDAEDFAWVQEEPANQGAWSFVALNLLEHLEGVRLRRISRPAAAAPAV
GSAKMHEAEQSALIEAALPRP
NT seq
3306 nt
NT seq
+upstream
nt +downstream
nt
atggatgcctcgctcgaggtgccgaccgccacgtcggtgcgggccatcccggccaagctg
ctggtcgacaaccgcatcgtgatcaacaatcacctcgcccgcgggcgcggcggcaaggtc
agcttcacccacctcatcggctgggcgctggtccgctcggtcaaggcgcacccggagatg
aacaactccttcgccgaggtggacggcaagccggccgtcgtgcagcccgagcacatcaac
ctcggcatcgccatcgacctcgccaagaaggacggcacgcggaccctcgtcgtgccctcc
atcaagaactgcgagcagatggacttccggcagttctggcaggcgtacgaggacgtggtc
cggcgcgcccgccgcaacgagctgaccatggacgactacgccggcaccaccatctcgctg
accaaccccggcggcatcggcacggtgcactccatcccgcgcctgatgagcggccagagc
gcgatcatcggcgtcggggcgatggagtaccccgcgccctactccggcatgtccgacgag
accctcaccgagcacggcgtcagcaaggtcaccacgctgaccagcacctacgaccaccgc
gtcatccagggtgcgcagtccggcgagttcctcaaggcgatgcacgagttcctgctcggc
gagcactcgttctacgacgacatcttcacctcgctgcggatcccgtacgagccggtccgc
tgggtgcgcgacgtcgcccggacctccgaggggcagatcgacaaggccgcccgggtggtc
gagctgatccacgcgtaccgggtgcgcggtcacctcatggccgacaccgacccgctcgag
ttcgagatccgccggcaccccgacctggacgtgctccagcacgggctgaccctgtgggac
ctcgaccggacgttcccggtcggcggcttcgccggcaagcagaagatgaagctgcgcgac
gtgctcggcgtgctgcgcgacacctattgccgccgggtcggcatcgagtacatgcacatc
cagggccccgaggagcggcgctggatccaggaccggatcgagatcaagtacacgaagccg
gaccaggaggagcagaagcacatcctcaaccggctcaacgcggccgaggcgttcgagacc
ttcctgcagaccaagttcgtcggtcagaagcggttctcgctggagggcggcgagtccctg
atcccgctgctcgacgccgtcctggagtcctcggccgaggccgggctcgacgagatggtc
atcggcatggcccaccgcggccggctcaacgtgctcgcgaacatcgtcggcaagccgtac
gaaaagatcttcaacgagttcgagggccagatggacccgaagtcggcccacggctccggc
gacgtgaagtaccacctcgggcagacgggcaagtacacgacgcccgacggcgagaattcc
accaccgtcagcgtggtcgccaacccgtcccacctggaggccgtcgacccggtcctcgag
ggcatcgtccgcgccaagcaggaccgcctcgacctgggcctgcacggctacacggtgctg
ccggtgctggtgcacggcgacgccgcgttcgccgggcagggcgtggtggccgagacgctc
aacctctcccagctgcgcggctaccgcaccggcggcacggtgcacgtcgtggtcaacaac
caggtcggcttcaccaccgccccggagtacagccgctcgtcgctctactcgaccgacgtc
gcgcgcatgatccaggcgccgatcttccacgtgaacggcgacgaccccgaggccgtcgta
cgggtcgcgaagctcgccttcgaataccgccaggcgttcaacaaggacgtcgtgatcgac
atggtctgctaccgccgccgcggtcacaacgagggcgacgacccgtcgatgaccaacccg
cggatgtaccagatcatcgacaccaagcgctcggtccgcaagctgtacaccgaggagctc
atcggccgcggcgacatcaccatcgacggcgcgcaggagcagctccgcgactaccagtcg
cagctcgagaaggtgttcaaggcgacccgcgactccgccggctcgccgccgcgggtgcgg
cccaccccgggcgacgagcccgagcccacggtggagagcgcggtcgacgcggccgtggtc
aagtccgtcggccaggcgcacgtcgacctgcccgagggcttcaccccgcacaagcgggtc
cagcagctgctcgagcggcgcgcccggatgtcggtcgagggcggcatcgactggggcttc
ggcgagctcgtcgcgttcggatccctgctcgcccagggcgtgaccgtacgcctcgccggc
caggactcccgccgcggcacgttcacctcgcggcacgcctccatcgtcgacgccaagacc
ggcgacgacttcctgccgctgtccacgctcgccaccggcaacgcccgcttcttcgtccac
gactccctgctcagcgagtacgcggcgatgggcttcgagtacggttactcggtcgagaac
ccggacgcgctggtgctgtgggaggcgcagttcggtgacttcgtcaacggcgcccagtcc
atcgtcgacgagttcatctcctccggcgaggtgaagtggggccagcagtcgtcgctggtg
ctgctcctcccgcacggccaggagggccagggcccggaccactcgtccggccggccggag
cggttcctgcagctctgcgcgcaggacaacatgcgggtggccaacccgaccaccccggcc
aactacttccacctgctgcgccgccaggcgctgtcgaccaagcgcaagccgctgatcgtc
ttctcgcccaagtccctgctgcgccacaagctcgcggtgtcgtcggtcgccgacttcacc
accggctcgttccagccggtgctcggcgacgcgggcatcaacggcaagccgctggacgcc
tcggcggtcaagcgggtgctgctctgctcgggcaaggtctactacgacctgttccaggcc
cgcgccgagcgcggcatcaccgacacggcgatcatccggatggagcagatctacccgctg
ccggtcgaggagctcaaggccgtcctccaccagttccccgacgcggaggacttcgcgtgg
gtccaggaggagccggccaaccagggcgcctggtcgttcgtggcgctgaacctcctcgag
cacctcgagggcgtccgcctgcggcgcatctcccgcccggcggcggccgcccccgcggtc
ggctcggcgaagatgcacgaggcggagcagtccgcgctgatcgaggcggccctgccccgc
ccctga
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