Actinomyces sp. oral taxon 414: AM609_09600
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Entry
AM609_09600 CDS
T04083
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
acq
Actinomyces sp. oral taxon 414
Pathway
acq00020
Citrate cycle (TCA cycle)
acq00630
Glyoxylate and dicarboxylate metabolism
acq00785
Lipoic acid metabolism
acq01100
Metabolic pathways
acq01110
Biosynthesis of secondary metabolites
acq01120
Microbial metabolism in diverse environments
acq01200
Carbon metabolism
acq01210
2-Oxocarboxylic acid metabolism
Module
acq_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
acq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AM609_09600 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AM609_09600 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AM609_09600 (kgd)
Enzymes [BR:
acq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AM609_09600 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AM609_09600 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AM609_09600 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AM609_09600 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ALD00702
UniProt:
A0A0M5JV53
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All DBs
Position
2367121..2371041
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AA seq
1306 aa
AA seq
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MVEEMRDAWRSDPASVGPRWRSLFEAEAAAPAATAAAESSDAGSTATGPATSQSATAGPT
ESPDPEGLAPAPPSGTAHPPADAQPPSDTAPRPRPAQDPAGPGAAPHRQILSIQDVTRSD
LPPAPPSGTAPPTSPYAQRLARQHRRNGGAGEDSSVRLRGAAARTAKNMEASLSIPTATS
ARAVPAKVLIENRAIINGHLAHTRGGRVSFTHLIGWAVVESLSEMPSMNVSYAVDDAGRP
VRHEPAHIAFGLAVDAPGPDGERRLLVPSVKRADLMDLAGFVAACEDLVRRAREGGLGVD
DFRGTTVTLTNPGMFGTLHSVPRLMPGQGLIVGVGAMDYPAAFAGAGEKTLARHGIGKTL
TLTSTYDHRVIQGAASGEFLRLVERKLLGLDGFWERAFESLRIPHEPVVWARDAVYDADL
ETGKPARVAELIHAFRQRGHLAADTDPLTYRLRRHPDLDITSYGLSLWDLDRAFPTGGLG
GTERATLREILNRLRDAYCRTAGIEYMHIQDPAQRAWWQERLEGEWPTTTPAERRRILTK
LEQAEAFETFLQTKYVGQKRFSLEGGESLIVALDRLLDAAAHDGLDEVVIGMTHRGRLNV
LTNIAGKSYGQVFDEFDGAGVVEGAGTGDVKYHLGTDGVFTGTDGVSTRVSLAANPSHLE
TVDGVVEGIVRAKQDRIGLGERGYTVMPVLVHGDAAFAGQGVVYETLNMSQLPAYRTGGT
VHIIVNNQIGFTTGSASARSTTYATDLAKGLQVPIFHVNADDPETVARAARLAYDYRAAF
HKDVIIDLICYRRRGHNEGDDPSMTQPVMYRLIDSLPSTRAVYTADLVGRGDITAEDARR
IERDSRDELERIFAETRAHARAARDRADRADPPPSNDTIDATDPTKVGLQTTGLEVPASQ
RAGQGMMIGWTSAVSRRVVERIGDAQVAHPPGFTVHPKLEAMLDGRRRATREGGIDWGLG
ELIAIGSLLMEGVPVRLAGEDARRATFAQRHAVLHDHVSGAEWTPLDFLTPDQAPLSVYD
SLLSEYAALAFEYGYAVERPEALTMWEAQFGDFANGAQCVIDEYVTSATQKWGQRSGLVM
LLPHGQEGQGPDHSSARIERYLLMCAQDNLRVAQPSTPANHFHLLREQAYSRPRRPLVVF
TPKQLLRLRAATSAVEDFTSGVFRPVIGETDPAIASDGAGAGVSRVLVCSGRVYYDLLAE
RARRREAAEEGSTVAIVRLEQLYPLPLEELAGALAPFAGAEVCWVQDEAANQGVWPYLGL
HLPESMTASGPVRLISRPEAAAPAVGSVRMYRADQARLIARAFARQ
NT seq
3921 nt
NT seq
+upstream
nt +downstream
nt
atggtggaggagatgcgcgacgcctggcgctccgaccccgcctcggtcggcccccggtgg
cgcagcctcttcgaagccgaagcggcggccccggccgcgaccgcggccgccgagagctcg
gacgccgggagcacagccaccgggcccgcaacatcccagtcggcgaccgccgggcccacc
gaaagcccagaccccgagggcctggcccccgccccgccgtcgggcaccgcgcacccgccg
gccgacgcgcagccgccgtctgacaccgcgccccgcccccggccggcgcaggacccggcg
ggcccgggcgcggcgccccaccgccagatcctctccatccaggacgtcacccgctcggac
ctgccgccggccccgccgtcgggcaccgccccgcccacctccccctacgcccagcgactg
gcccgccagcaccgccgcaacggcggcgccggcgaggactcctccgtccgcctcaggggc
gccgccgcgcgcaccgccaagaacatggaggcctcgctgtccatccccacggcgacgtcc
gcccgcgccgtccccgccaaggtcctcatcgagaaccgcgccattatcaacggccacctg
gcccacacccgcggtggcagggtctccttcacccacctcatcggctgggcggtggtggag
tccctgtcggagatgccctccatgaacgtctcctacgccgtcgacgacgccggccggccc
gtgcgccacgagcccgcgcacatcgccttcggcctggccgtcgacgcacccggccccgac
ggcgagcgccgtctgctcgtgccctccgtcaagagggccgacctcatggacctggcgggc
ttcgtggccgcctgcgaggacctcgtgcgccgggcgcgcgagggcgggctcggcgtcgac
gacttccgcggcaccaccgtgaccctgaccaaccccggcatgttcggcaccctccactcg
gtgccccgcctcatgcccggccagggcctcatcgtcggcgtgggggccatggattacccg
gccgccttcgccggcgccggcgagaagaccctcgcccgccacggcatcggcaagaccctc
accctgacctccacctacgaccaccgcgtcatccaaggagcggcctccggcgagttcctg
cggctggtggagcgcaagctgctgggcctggacgggttctgggagcgggccttcgagtcc
ctgcgcatcccgcacgagccggtcgtctgggcccgcgacgccgtctacgacgccgacctg
gagaccggcaagcccgcgcgcgtggccgaactcatccacgccttccgccagcgcgggcac
ctggccgccgacaccgacccgctcacctaccgcctgcgccgccacccggacctggacatc
acctcctacggactgagcctgtgggacctggaccgtgccttccccaccggcggcctgggc
ggcaccgagcgcgccaccctgcgcgagatcctcaaccgcctgcgcgacgcctactgccgc
accgccggcatcgagtacatgcacatccaggaccccgcccagcgcgcctggtggcaggag
cgcctggagggcgagtggccgacgaccacccccgccgagcgccgtcggatcctgaccaag
ctggagcaggccgaggccttcgagaccttcctgcagaccaagtacgtgggccagaagcgc
ttcagcctggagggcggggagtccctcatcgtggccctggaccggctgctggacgccgcc
gcccacgacggcctggacgaggtcgtcatcggcatgacccaccgcggccgcctcaacgtg
ctgaccaatatcgccggcaagtcctacgggcaggtcttcgacgagttcgacggcgccggc
gtcgtcgagggcgccggcaccggcgacgtcaagtaccacctgggcaccgacggcgtcttc
accggcaccgacggcgtgtccacccgcgtgtccctggccgccaacccctcccacctggag
acggtcgacggcgtcgtcgaggggatcgtgcgcgccaagcaggaccgcatcggcctgggt
gagaggggctacacggtcatgccggtgctcgtgcacggcgacgccgccttcgccgggcag
ggcgtggtctacgagaccctcaatatgagccagctgcccgcctaccgcaccggtggcacc
gtgcacatcatcgtcaacaaccagatcggcttcaccaccgggtcggcctccgcccgctcg
accacctacgccaccgacctggccaaggggctgcaggtgcccatcttccacgtcaacgcc
gacgaccccgagacggtggcccgcgccgcccgcctcgcctacgactaccgggcggccttc
cacaaggacgtcatcatcgacctcatctgctaccggcgccgcggtcacaacgagggcgac
gacccgtcgatgacccagccggtcatgtaccgcctcatcgactccctgccctcgacccgc
gcggtctacaccgccgacctggtggggcgcggggacatcaccgccgaggacgcccggcgg
atcgagcgcgactcccgcgacgagctggagcggatcttcgccgagacccgggcccacgcg
cgggcggcccgcgaccgcgccgatcgcgccgacccgccgccctccaacgacacgatcgac
gccaccgaccccaccaaggtgggcctgcagaccaccggattggaggtgcccgcctcccag
cgcgcaggccagggcatgatgatcggctggaccagcgcggtctcgcgccgcgtcgtcgag
cgcatcggggacgcgcaggtcgcccacccgccgggcttcaccgtccaccccaaactggag
gccatgctcgacgggcgccggcgcgccacccgggagggcggcatcgactgggggctgggc
gagctcattgcgatcggttccctgctcatggagggggtgccggtgcgcctggccggcgag
gacgcccgccgcgccaccttcgcccagcgccacgccgtcctgcacgaccacgtctcgggc
gccgagtggacgccgctggacttcctgaccccggaccaggcgccgctgagcgtctacgac
tccctgctcagcgagtacgcggccctggccttcgagtacggctacgccgtcgagaggccg
gaggcgctgaccatgtgggaggcccagttcggcgacttcgccaacggcgcccagtgcgtc
atcgacgagtacgtcacctccgccacccagaagtgggggcagcgctccgggctggtcatg
ctcctgccccacggccaggagggtcaggggcccgaccactcctcggcgcgcatcgagcgc
tacctgctcatgtgcgcgcaggacaacctgcgggtggcccagccctccacgcccgccaac
cacttccacctgctgcgcgagcaggcctactcgcggccgcgccgcccactcgtcgtcttc
acgcccaagcagctgctgcgcctcagggccgccacgagcgcggtggaggacttcacctcc
ggggtcttccggccggtcatcggcgagacggacccggccatcgcctccgacggcgcgggc
gcgggcgtgagccgggtgctggtgtgctccgggcgcgtctactacgacctgctggccgag
cgggcccgacggcgggaggcggcggaggagggctccacggtggccattgtgcgtctggag
cagctctacccgctgcccctcgaggagctggccggggccctggcccccttcgccggggcc
gaggtgtgctgggtgcaggacgaggcggcgaaccagggcgtgtggccctacctcggcctg
cacctgccggagtcgatgacggcgtcgggcccggtgcgcctgatctcccggcccgaggcc
gccgcccccgccgtcggcagcgtcaggatgtaccgggccgaccaggcccggctcatcgcc
cgggccttcgcccggcagtga
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