Actinomyces capricornis: MANAM107_04180
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Entry
MANAM107_04180 CDS
T09393
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
acap
Actinomyces capricornis
Pathway
acap00020
Citrate cycle (TCA cycle)
acap00630
Glyoxylate and dicarboxylate metabolism
acap00785
Lipoic acid metabolism
acap01100
Metabolic pathways
acap01110
Biosynthesis of secondary metabolites
acap01120
Microbial metabolism in diverse environments
acap01200
Carbon metabolism
acap01210
2-Oxocarboxylic acid metabolism
Module
acap_M00009
Citrate cycle (TCA cycle, Krebs cycle)
acap_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
acap00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MANAM107_04180 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MANAM107_04180 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MANAM107_04180 (kgd)
Enzymes [BR:
acap01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MANAM107_04180 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MANAM107_04180 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MANAM107_04180 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MANAM107_04180 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BDA63584
LinkDB
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Position
516657..520469
Genome browser
AA seq
1270 aa
AA seq
DB search
MPTQDRPAPRSSAGFGANEWIVEEMRAAWSADPASVSTQWRELFEADPQAGQALQGAAAP
DPLEGPRRATITASSAPSAPRTASAVQDVSRSDLPPAPPSDAAPPTSPYAQRRAALQAQD
PSGQGGQGAATRLKGAAARTAKNMEESLSVPTATSARAVPAKVLIENRAVINAHLSHTRG
GKVSFTHLIGWAVVEALTEMPGMNVSYSVDEAGKPMLNTPAHVAFGLAVDVPGADGERRL
LVPSIKQADLMDLAGFVAAYEQLVSRARQGGLELADFQGTTVTLTNPGMLGTLHSVPRLM
PGQGLIVGVGSMDYPAAFAGASAETLARQGIGKILTLTSTYDHRVIQGAASGEFLRLVER
KLLGLDGFWDRALASLRIPHEPVRWARDSTYDPELETGKPARVAELIHAFRQRGHLAADT
DPLTYRLRRHPDLDIASYGLSLWDLDRTFPTGGLGGRERATLREILEMLRGAYCRTVGVE
YMHIQDPAQRTWWQERLETDWREIDHAERRRILSKLEQAEAFETFLQTKYVGQKRFSLEG
GESLIVLLDRLLDSCAHDGLDEVVIGMAHRGRLNVLTNIAGKSYSQVFDEFDGNSVIEGA
STGDVKYHLGTEGVFTGTDGVSTRVSLAANPSHLETVDGVVEGIVRAKQDRIGLGEKGYT
VLPVLVHGDAAFAGQGVVYETLNMSQLPAYRTGGTVHVVVNNQIGFTTGAASARSTTYAT
DLAKGLQVPIFHVNADDPDTVARAAHLAYEYRRTFHKDVIIDLICYRRRGHNEGDDPSMT
QPVMYRLIDSLPSTRQVYTSALVGRGDITAQEAEELAAEYHDELERVFSEARAQAGGAEG
APEGRSAAETQDFSDPARVGIPRSSLEIPASQQAGSGMMLGWTSAVPRDVIERIGDAQVA
WPPSFRVHPKLEAMLAKRQSSSREGGIDWGFGELLALGSLLMEGVPVRLAGEDARRATFS
QRHAVLHDHDSGAEWTPLSFLTPDQASLEIYDSLLSEYAALAFEYGYSVERPEGLTMWEA
QFGDFANGAQSVIDEYVTSATQKWGQRSGLVMLLPHGQEGQGPDHSSARIERYMQMCAQD
NMWVAQPSTPANHFHLLREHAYRRPRRPLIVFTPKQLLRLKAATSPVEDFTSGAFQPVIG
EVDAGLAASGEVDRVLLCSGRVYYDLLAHRQATGDTRTAIIRLEQLYPLDAEAISAALAP
FAGAEPVWVQDEPANQGMWPYLALHLPVELTGGVLPGLVSRPEAAAPAVGAAGAFRAQQE
ELVARAFARD
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgcccacgcaggaccgccccgccccacgatccagcgcaggattcggagccaacgagtgg
atagtggaggagatgcgggccgcctggtccgccgaccccgcctccgtgagcacccagtgg
cgcgagctcttcgaggccgacccccaggccgggcaggccctgcagggcgccgccgccccc
gaccccctggagggcccccggcgggccacgatcaccgcctcctcggcaccctcggcgccc
cgcaccgcctccgccgtccaggacgtcagccgctcggacctgccgcccgcgccgccgtcg
gacgccgccccgcccacctccccctacgcccagcgccgggccgccctccaggcccaggac
ccctcgggccaaggcggccagggcgcggccacccgcctcaagggcgccgccgcccgcacc
gccaagaacatggaggagtccctgtcggtgcccacggccacctcggctcgcgcggtgccc
gccaaggtcctcatcgagaaccgggccgtcatcaacgcccacctgtcccacacccgcggg
ggcaaggtctccttcacccacctcatcgggtgggccgtggtcgaggcgctcaccgagatg
ccggggatgaacgtgtcctactccgtggacgaggccggcaagccgatgctcaacaccccg
gcgcacgtcgccttcggcctggccgtggacgtgcccggggccgacggcgagcgccgcctc
ctggtgccctccatcaagcaggccgacctcatggacctggccggcttcgtggccgcctac
gagcagctggtctcccgggcccggcagggcggcctcgagctcgccgacttccagggcacc
accgtgaccctgaccaaccccggcatgctcggcaccctgcactccgtgccgcggctcatg
cccggccaggggctcatcgtgggggtcggctccatggactacccggcggccttcgccggc
gccagcgccgagaccctggcccgccagggcatcggcaagatcctgaccctgacctccacc
tacgaccaccgcgtcatccagggggcggcctccggggagttcctgcggctggtggagcgc
aagctcctgggcctggacggattctgggaccgggccctggcctccctgcgcatcccgcac
gagccggtgcgctgggcccgcgactccacctacgaccccgagctggagaccggcaagccc
gcgcgcgtggccgagctcatccatgccttccgccagcgcggccacctggccgccgacacc
gatccgctgacctaccgcctgcggcgccaccccgacctggacatcgcctcctacgggctg
agcctgtgggacctggaccgcaccttccccaccggcgggctgggtggccgcgagcgcgcc
accctgcgcgagatcctggagatgctgcggggcgcctactgccgcaccgtcggggtggag
tacatgcatatccaggaccccgcccagcgcacctggtggcaggagcgcctggagaccgac
tggagggagatcgaccacgccgagcggcgccgcattctgtccaagctggagcaggccgag
gccttcgagaccttcctgcagaccaagtacgtgggccagaagcgcttcagcctggagggc
ggggagtccctcatcgtgctgctggaccgcctcctggactcctgcgcccatgacggcctg
gacgaggtggtcatcggcatggcccaccgcgggcgcctcaatgtgctgaccaatatcgcc
gggaagtcctacagccaggtcttcgacgagttcgacggcaacagcgtcatcgagggcgcc
agcaccggcgacgtgaagtaccacctgggcaccgagggcgtgttcaccggcaccgacggg
gtctccacccgcgtgtccctggccgccaacccctcccacctggagaccgtcgacggcgtt
gtggaggggatcgtgcgggccaagcaggaccgcatcggcctgggcgagaaggggtacacg
gtcctgccggtcctggtccacggcgatgcggccttcgccgggcagggcgtggtctacgag
accctcaacatgagccagctgcccgcctaccgcaccggcggcaccgtccacgtggtggtc
aacaaccagatcggcttcaccacgggggcggcctcggcgcgctcgaccacctacgccacc
gacctggccaagggcctgcaggtgccgatcttccacgtcaacgccgatgaccccgacacg
gtggcgcgtgccgcccacctggcctacgagtaccggcgcaccttccacaaggacgtcatc
atcgacctcatctgctaccggcgccgcgggcacaacgagggtgacgacccctcgatgacc
cagccggtcatgtaccgcctcatcgactccctgccctcgacccgccaggtctacacctcc
gccctcgtgggccgcggcgacatcaccgcccaggaggccgaggagctggccgcggagtac
cacgacgagctggagcgggtcttctccgaggcccgtgcccaggccgggggcgccgagggc
gccccggagggccggtccgccgccgagacccaggacttctccgaccccgccagggtgggc
atcccgcgctcctccctggagatccccgcctcccagcaggccggctcgggcatgatgctg
ggctggacctcggcggtgccgcgcgatgtcatcgagcgcatcggggatgcccaggtggcc
tggcctccctccttccgcgtccaccccaagctggaggcgatgctggccaagcgccagtcc
tcctcgcgcgagggcggcatcgactggggcttcggggagctgctggccctgggcagcctg
ctcatggagggggtgccggtgcgcctggccggggaggacgcgcgccgggccaccttctcc
cagcgccacgccgtcctgcacgaccacgactcgggggcggagtggacgccgctgagcttc
ctgacccccgaccaggcctccctggagatctacgactccctgctcagcgagtacgcggcc
ctggccttcgagtacggctactcggtggagcgccccgaggggctgaccatgtgggaggcc
cagttcggcgacttcgccaatggggcccagagcgtcatcgacgagtacgtcacctcggcc
acccagaagtgggggcagcgctcgggcctggtcatgctcctgccccacggccaggagggc
caggggcccgaccactcctcggcgcgcatcgagcgctacatgcagatgtgcgcccaggac
aatatgtgggtcgcccagccctcgaccccggccaaccacttccacctgctgcgcgagcac
gcctaccggcgcccgcgccgcccgctcatcgtcttcacccccaagcagctgctgcggctc
aaggcggccacctcccccgtggaggacttcacctccggggccttccagcccgtcatcggg
gaggtcgacgcgggccttgccgccagcggcgaggtggaccgggtgctgctgtgctcgggg
cgggtctactacgacctgctggcccaccgtcaggccaccggcgatacccgcaccgccatc
atccgcctggagcagctctaccccctggatgccgaggccatcagcgcggccctggccccc
ttcgcgggcgcggagccggtctgggtccaggacgagcccgccaaccagggcatgtggccc
tacctggccctgcacctgcccgtggagctgaccgggggcgtcctgccggggctggtctcg
cgccccgaggccgccgcgcccgccgtgggcgccgcgggggccttccgcgcccagcaggag
gagctggtggcccgcgccttcgcccgcgactga
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