KEGG   REACTION: R13122
Entry
R13122                      Reaction                               
Name
5-dehydro-6-demethoxyfumagillol,2-oxoglutarate:oxygen oxidoreductase (6-hydroxylating)
Definition
5-Dehydro-6-demethoxyfumagillol + 2-Oxoglutarate + Oxygen <=> 5-Dehydro-6-demethoxy-6-hydroxyfumagillol + Succinate + CO2
Equation
C22629 + C00026 + C00007 <=> C22631 + C00042 + C00011
Enzyme
1.14.11.82
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00969  Fumagillin biosynthesis, farnesyl-PP => fumagillin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.82
     R13122  5-Dehydro-6-demethoxyfumagillol + 2-Oxoglutarate + Oxygen <=> 5-Dehydro-6-demethoxy-6-hydroxyfumagillol + Succinate + CO2
Orthology
K22570  5-dehydro-6-demethoxyfumagillol dioxygenase [EC:1.14.11.82]
Other DBs
RHEA: 74638
LinkDB

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