REACTION: R02834
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Entry
R02834 Reaction
Name
cortisol:NAD+ 11-oxidoreductase
Definition
Cortisol + NAD+ <=> Cortisone + NADH + H+
Equation
C00735
+
C00003
<=>
C00762
+
C00004
+
C00080
Comment
NADP+ (see
R02836
)
Reaction class
RC00001
C00003_C00004
RC00154
C00735_C00762
Enzyme
1.1.1.-
Pathway
rn00140
Steroid hormone biosynthesis
rn01100
Metabolic pathways
Module
M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.-
R02834 Cortisol + NAD+ <=> Cortisone + NADH + H+
BRITE hierarchy
Orthology
K00071
corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
Other DBs
RHEA:
50211
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