KEGG   NETWORK: N01686
Entry
N01686                      Network                                
Name
Lysine degradation 2
Definition
2-OA+Lipoyl-E2 -- DHTKD1 >> DLST -> Glutaryl-CoA+Dihydrolipoyl-E2
  Expanded
C00322+C15972 -- 55526 >> 1743 -> C00527+C15973
Class
nt06036 Lysine degradation
nt06032 Lipoic acid metabolism
Type
Reference
Pathway
hsa00310  Lysine degradation
Gene
55526  DHTKD1; dehydrogenase E1 and transketolase domain containing 1
1743  DLST; dihydrolipoamide S-succinyltransferase
Metabolite
C00322  2-Oxoadipate
C15972  [E2 protein] N6-(lipoyl)lysine
C00527  Glutaryl-CoA
C15973  [E2 protein] N6-(dihydrolipoyl)lysine
Reference
PMID:32768327
  Authors
Leandro J, Houten SM
  Title
The lysine degradation pathway: Subcellular compartmentalization and enzyme deficiencies.
  Journal
Mol Genet Metab 131:14-22 (2020)
DOI:10.1016/j.ymgme.2020.07.010
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