KEGG ORTHOLOGY: K24034

ORTHOLOGY: K24034

Entry

K24034                      KO

Symbol

SPE3-LYS9

Name

spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming) [EC:2.5.1.16 1.5.1.10]

Pathway

map00270

Cysteine and methionine metabolism

map00300

Lysine biosynthesis

map00310

Lysine degradation

map00330

Arginine and proline metabolism

map00480

Glutathione metabolism

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01230

Biosynthesis of amino acids

Module

M00030

Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine

Reaction

R01920

S-adenosylmethioninamine:putrescine 3-aminopropyltransferase

R02315

N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase

R08359

S-adenosylmethioninamine:cadaverine 3-aminopropyltransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
   00300 Lysine biosynthesis
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
   00310 Lysine degradation
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
   00330 Arginine and proline metabolism
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.10  saccharopine dehydrogenase (NADP+, L-glutamate-forming)
     K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.16  spermidine synthase
     K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)

Other DBs

COG:	COG0421 COG1748

GO:	0004766 0004755

Genes

CNE:

CNG01150

CNB:

CNBG3640

CNG:	CNAG_03476

CGI:	CGB_G5220C

CDEU:

CNBG_2136

CDEP:

91085546(L203_101333)

KMG:	30159916(I203_104953)

KNE:	92180591(IAR55_003333)

TMS:	TREMEDRAFT_74272

TASA:

A1Q1_06672

CCAC:

CcaHIS019_0502360(LYS9)

TVS:	TRAVEDRAFT_53623

DSQ:	DICSQDRAFT_85486

PCO:	PHACADRAFT_187523 PHACADRAFT_262714

SHS:	STEHIDRAFT_76391

HIR:	HETIRDRAFT_471805

PSQ:	PUNSTDRAFT_145068

ADL:	AURDEDRAFT_115750

FME:	FOMMEDRAFT_112965

GTR:	GLOTRDRAFT_139895

RSX:	RhiXN_07834

LBC:	LACBIDRAFT_177008

CCI:	CC1G_05582

ABP:	AGABI1DRAFT64147(AGABI1DRAFT_64147)

ABV:	AGABI2DRAFT184364(AGABI2DRAFT_184364)

PCUB:

JR316_0012084

MRR:	Moror_16977

E1B28_013447

SCM:	SCHCO_02542524(SCHCODRAFT_02542524) SCHCO_02628453(SCHCODRAFT_02628453)

CPUT:

CONPUDRAFT_84267

SLA:	SERLADRAFT_362472

WSE:	WALSEDRAFT_31404

WIC:	J056_002184

UMA:	UMAG_05818

PFP:	PFL1_02581

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_06954

PTRC:

PtA15_5A90

PSTR:

Pst134EA_009050

MLR:	MELLADRAFT_73077 MELLADRAFT_91581

» show all

Reference

PMID:15189996

Authors

Kingsbury JM, Yang Z, Ganous TM, Cox GM, McCusker JH

Title

Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans.

Journal

Eukaryot Cell 3:752-63 (2004)
DOI:10.1128/EC.3.3.752-763.2004

Sequence

[cne:CNG01150]

LinkDB

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