KEGG   ORTHOLOGY: K21292
Entry
K21292                      KO                                     
Symbol
CYP503
Name
ent-kaurene oxidase [EC:1.14.14.86]
Pathway
map00904  Diterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Reaction
R06291  ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
R06292  ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
R06293  ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
R10066  ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K21292  CYP503; ent-kaurene oxidase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K21292  CYP503; ent-kaurene oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.86  ent-kaurene monooxygenase
     K21292  CYP503; ent-kaurene oxidase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP503 family
   K21292  CYP503; ent-kaurene oxidase
Other DBs
COG: COG2124
GO: 0052615
Genes
PAN: PODANSg1224 PODANSg7998
PBEL: QC761_202100 QC761_501290
PPSD: QC762_202100 QC762_501290
PPSP: QC763_202100 QC763_501290
PPSA: QC764_202100 QC764_501290
PPEI: PpBr36_02038
PGRI: PgNI_07976 PgNI_07987 PgNI_10620 PgNI_11810
FPOA: FPOAC1_001978
FVN: FVRRES_02217
FVR: FVEG_16575
TATV: 25776384(TrAtP1_010953)
TASP: 36611072(TrAFT101_010788) 36615435(TrAFT101_009131)
MBRN: 26245739(ltmK)
CDET: 87938838(CDEST_02335) 87942428(CDEST_05925) 87949436(CDEST_12936)
CPW: 9694506(D8B26_005570)
ABE: ARB_00548
TVE: TRV_00376
PTE: PTT_08290
ZTR: MYCGRDRAFT_34461(CYP-58)
AG: CAA76703(CYP503A1)
 » show all
Reference
PMID:11472927 (CYP503A1)
  Authors
Tudzynski B, Hedden P, Carrera E, Gaskin P
  Title
The P450-4 gene of Gibberella fujikuroi encodes ent-kaurene oxidase in the gibberellin biosynthesis pathway.
  Journal
Appl Environ Microbiol 67:3514-22 (2001)
DOI:10.1128/AEM.67.8.3514-3522.2001
  Sequence
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