KEGG ORTHOLOGY: K20667

ORTHOLOGY: K20667

Entry

K20667                      KO

Symbol

CYP716A

Name

beta-amyrin 28-monooxygenase [EC:1.14.14.126]

Pathway

map00999

Biosynthesis of various plant secondary metabolites

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00971

QS-7 biosynthesis, 2,3-epoxysqualene => QS-7

Reaction

R10924

beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (28-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various plant secondary metabolites
    K20667  CYP716A; beta-amyrin 28-monooxygenase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K20667  CYP716A; beta-amyrin 28-monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.126  beta-amyrin 28-monooxygenase
     K20667  CYP716A; beta-amyrin 28-monooxygenase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, plant type
  CYP716 family
   K20667  CYP716A; beta-amyrin 28-monooxygenase

Genes

ATH:	AT5G36110(CYP716A1) AT5G36130 AT5G36140(CYP716A2)

ALY:

9304531

CRB:

17878597

CSAT:

104719298 104724031 104732576

EUS:	EUTSA_v10027740mg

THJ:

104808921

CPAP:

110811366

CIT:	102613788 102620622 102625141 102625960

CIC:	CICLE_v10001024mg CICLE_v10010450mg CICLE_v10019890mg CICLE_v10019893mg CICLE_v10030148mg

PVY:	116104854 116107899 116112247 116115260 116119093 116124678 116130216 116130217 116136621 116140662 116140977 116143340 116147033

MINC:

123201025 123201638 123201807 123202365 123205827 123218458 123218589 123218629 123219553 123220675 123226276 123226277 123227278 123228571 123229810 123229811

TCC:	18587560 18589551 18593052 18593053 18593056 18595104 18595548 18595550

GRA:	105767622 105776509 105781233 105781243 105790134

GHI:	107895081 107903232 107919059 107919062 107925135 107926136 107930304 107961323 107963597 121204862

GAB:	108451497 108462699 108465546 108477746 108488461

HSYR:

120124470 120128851 120131435 120133421 120142418 120182578 120183353 120202788

DZI:	111274103 111275451 111278006 111278701 111280632 111280689 111280756 111281159 111301786

EGR:	104435880 104437292 104437293 104441237 104444333 104444335 104448666 104450761 104457239 120293659 120293667 120293668 120294348

GMX:	100801007 100813159 100815640

GSJ:	114413490 114422693 114423706

PVU:	137809820 137826724 137827039

VRA:	106758067 106758467 106767963

VAR:

108322903

VUN:	114176393 114183790

VUM:	124820552 124845221

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:

ADU:

AIP:	107615408 107630659

AHF:	112701162 112723369 112732385 112790749

LANG:

109333199

PCIN:

129296548 129298412 129301471 129303640 129307971 129322593

QSA:	O6P43_003868 O6P43_005319 O6P43_023265 O6P43_023267

FVE:	101291154 101291788 101291806 101292094 101293769 101296436 101299517 101299572 101301540 101302728 101306530 101307150 101315239

AANS:

126786691 126786692 126787283 126789362 126790706 126792399 126795126 126801908

RCN:	112164676 112165857 112166483 112166646 112166908 112175390 112177319 112185234 112187334 112195973 112197476 112198001 112198294 112198580 112200323 112201067

PPER:

18774379 18778487 18780496 18780695 18791516

PMUM:

103324310 103325325 103325326 103326766 103326773

PAVI:

110744354 110748403 110759046 110764932 110764933 110764934 110764935 110774275

PDUL:

117620802 117624361 117624362 117624363 117624364 117630226 117630227 117630228

MDM:	103403131 103413895 103422316 103443518 103447994 103450666 103450667 103451601 103453334 108169263

MSYL:

126587952 126589645 126591578 126595747 126597528 126610146 126619690 126621076

PXB:	103929876 103936039 103937151 103942732 103945098 103949490 103954090 103965050

ZJU:	107403276 107403288 107429363 107429366 107433852 112489518 125422327 132799058 132800196

MNT:	21387441 21400536 21408617 21408619

CSAV:

115696903 115696978 115709530

CSV:

101206033

CMO:

103487187

BHJ:	120069984 120070901

MCHA:

CMAX:

CMOS:

CPEP:

RCU:	8260767 8262747 8281375 8282082 8282102 8282886 8283916 8283918

MEAN:

126661019 126662307 126666805 126667009 126667229 126668978 126675482

JCU:	105628799 105629842 105629863 105636944 105638311

HBR:	110638318 110642272 110643171 110643683 110647242 110648741 110652575 110657288 110657451 110658295 110658320 110672785 110673693

MESC:

110602890 110606971 110608454 110619201 110621545 110625163 110625349 110631281 110631302

POP:	18095771 18104396 18107881 7455277 7465578 7467407 7484042 7487256 7489100 7490471 7490472 7490478 7494429

PEU:	105108453 105108454 105110592 105110597 105111268 105119892 105120887 105120971 105120974 105122459 105130438 105130636 105136784

PALZ:

118029072 118035471 118035472 118040121 118040788 118050537 118052035 118052045 118056475 118056647 118056648

PNZ:	133668260 133668664 133669573 133669618 133672462 133673658 133673707 133673731 133674009 133674798 133689537 133702138 133703435

JRE:	108987665 108989511 108989520 108993145 108996978 109000648 109000986

CILL:

122274987 122297779 122298361 122298391 122298465 122299529 122318267

CAVE:

132175679 132176092 132183579 132184488 132185693 132189479 132189482 132190357 132190428 132190436 132190472

QSU:	111984387 111984580 111994391 111996765 112003765 112007351 112009785 112012433 136061986

TWL:	119982100 119982398 119986646 119989054 119989055 120005290 120006586 120006591 120008479 120014774 120016355

VVI:	100241454 100242305 100242468 100244714 100246675(CYP716A17) 100251813(CYP716A15) 100255183 100260260 100262400 100265713

VRI:	117905739 117907616 117910159 117910160 117913383 117923946 117924581 117924919 117924946 117932528 117932530 117932534 117932600 117932645

SLY:	101251676 101252500 101252702 101263783 101267575

SPEN:

107004210 107010425 107019970 107022868 107025690

SOT:	102579553 102580977 102581212 102581319 102593268 102597003 102603547

SSTN:

125844401 125848263 125852189 125852191 125869360 125872651 125876484 125877297

SDUL:

129874825 129880602 129893123 129898820 129903207 129903413 129903466

CANN:

107845824 107853551 107859002 107870851 107872609 107874833

LBB:	132599628 132615894 132618032 132618881 132622809 132624664 132636946 132640889

NTA:	107773209 107776438 107785337 107785342 107791887 107796228 107797155 107804791 107813374 107819508 107821306 107828908 107832734

NSY:	104211333 104211642 104219137 104219138 104227815 104233149 104234536 104235217

NTO:	104088247 104093962 104096561 104103477 104112260 104112489

NAU:	109209295 109209296 109234271 109236645 109239546 109240000 109244115

INI:	109146947 109164652 109164671 109169662 109179364

ITR:	116012044 116021251 116025198 116032834

SIND:

105159528 105159533 105161986 105167242 105173756 105175834 105177626

OEU:	111365629 111366330 111374946 111374953 111396592 111401849 111401850 111401851 111407310 111409118

EGT:	105951315 105956980 105956981 105956983 105969716 105969717 105970015 105970135 105970583 105970799 105970879 105970880 105970881 105970993 105971315 105974197 105974461 105974503

SSPL:

121750743 121761066 121761221 121769807 121778775 121779379 121779399 121779508 121781093 121781869 121783185 121784991 121785950 121787945 121793371 121801638 121805162

SMIL:

130988356 130988372 131003012 131009691 131010047 131010052 131010056 131010057 131010058 131010141 131010143 131010145 131010146 131010147 131010148 131010152 131017742 131021396

SHIS:

125191080 125192659 125193514 125197414 125203422 125206062 125206064 125206716 125206718 125212910 125216870 125217053 125218485 125224035

APAN:

127249804 127257504 127264669 127264670 127264926 127264966 127265080

HAN:	110886222 110894027 110894028 110894029 110907692 110927675 110940300

ECAD:

122593012 122597632 122597687 122602054 122604278

LSV:	111885055 111887682 111910266 111918815 111918848 111918849

CCAV:

112501106 112505577 112505866 112507837 112516599

DCR:	108192226 108192257 108192646 108194654 108195645 108198064 108202436 108208468 108216852 108217329 108218261 108225030

CSIN:

114257034 114267580 114269128 114277196 114277247 114278205 114281982 114281988 114285143 114285169 114292526 114292537 114299407 114299408 114304324 114304962 114307165 114310542 114322374

AEW:	130755812 130756802 130761298 130763515 130767376 130771626 130772291 130777959 130782013 130783107 130783116 130786170 130786207

BVG:	104886873 104908688

SOE:	110774665 110783981 110784965 110785568 110785594 110785600

CQI:	110683677 110687936 110710394 110714192 110714258 110715057 110715083 110715088 110715095 110715110 110725244 110725247 110725248 110726788 110730556

ATRI:

130798356 130808690 130813309

MOF:	131151629 131151630 131151632 131165878 131166051 131166194

NNU:	104589205 104590700 104593846 104593852

MING:

122068830 122094731

TSS:	122643208 122648217

PSOM:

113272949 113295481 113324411 113326675 113328770 113329441 113329901 113338734 113362114 113362147

MSIN:

131227071 131250001 131251198

ATR:	105421251 18425136 18441950 18441952 18441953 18441954 18441956

CJF:	131037219 131037232 131042241 131042254 131051115 131051116 131051118 131061015 131063082 131063138 131064721 131065500 131065501 131065503 131072733 131875057

AG:	AFO63032(CYP716A52v2) AHF22088(CYP716A75) CBN88269(CYP716A12)

» show all

Reference

PMID:21821776 (CYP716A12)

Authors

Carelli M, Biazzi E, Panara F, Tava A, Scaramelli L, Porceddu A, Graham N, Odoardi M, Piano E, Arcioni S, May S, Scotti C, Calderini O

Title

Medicago truncatula CYP716A12 is a multifunctional oxidase involved in the biosynthesis of hemolytic saponins.

Journal

Plant Cell 23:3070-81 (2011)
DOI:10.1105/tpc.111.087312

Sequence

[ag:CBN88269]

Reference

PMID:25578277 (CYP716A75)

Authors

Moses T, Pollier J, Faizal A, Apers S, Pieters L, Thevelein JM, Geelen D, Goossens A

Title

Unraveling the triterpenoid saponin biosynthesis of the African shrub Maesa lanceolata.

Journal

Mol Plant 8:122-35 (2015)
DOI:10.1016/j.molp.2014.11.004

Sequence

[ag:AHF22088]

Reference

PMID:26801524 (CYP716A1 CYP716A2)

Authors

Yasumoto S, Fukushima EO, Seki H, Muranaka T

Title

Novel triterpene oxidizing activity of Arabidopsis thaliana CYP716A subfamily enzymes.

Journal

FEBS Lett 590:533-40 (2016)
DOI:10.1002/1873-3468.12074

Sequence

[ath:AT5G36110 AT5G36140]

LinkDB

DBGET integrated database retrieval system