KEGG   ORTHOLOGY: K19974
Entry
K19974                      KO                                     
Symbol
acbO
Name
2-epi-5-epi-valiolone 7-phosphate 2-epimerase [EC:5.1.3.35]
Pathway
map00525  Acarbose and validamycin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00814  Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
Reaction
R11081  2-epi-5-epi-valiolone-7-phosphate 2-epimerase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00525 Acarbose and validamycin biosynthesis
    K19974  acbO; 2-epi-5-epi-valiolone 7-phosphate 2-epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.35  2-epi-5-epi-valiolone 7-phosphate 2-epimerase
     K19974  acbO; 2-epi-5-epi-valiolone 7-phosphate 2-epimerase
Other DBs
COG: COG1082
Genes
SERA: Ser39006_003970
SERQ: CWC46_03970
BIZ: HC231_14635
PALF: K6R05_03045
CVC: BKX93_19965
MMEI: LRP31_12205
AVF: RvVAR031_pl04700
AVM: JQX13_08255
AGAT: RWV98_05130 RWV98_11890 RWV98_19295
ECLF: QMP25_11395
MUL: MUL_0548
MMI: MMAR_0583
SALS: SLNWT_0593
SLE: sle_45850(sle_45850)
SAUH: SU9_022215
STPB: QR97_23295
KUT: JJ691_27090(acbO)
ACTI: UA75_21520
ACAD: UA74_21040
ASE: ACPL_3679(acbO)
ACTS: ACWT_3551
 » show all
Reference
  Authors
Zhang CS, Podeschwa M, Altenbach HJ, Piepersberg W, Wehmeier UF
  Title
The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase.
  Journal
FEBS Lett 540:47-52 (2003)
DOI:10.1016/S0014-5793(03)00221-7
  Sequence
[ase:ACPL_3679]
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