KEGG   ORTHOLOGY: K18649
Entry
K18649                      KO                                     
Symbol
IMPL2
Name
inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15]
Pathway
map00053  Ascorbate and aldarate metabolism
map00340  Histidine metabolism
map00562  Inositol phosphate metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
map04070  Phosphatidylinositol signaling system
Module
M00026  Histidine biosynthesis, PRPP => histidine
Reaction
R01185  1D-myo-inositol 1-phosphate phosphohydrolase
R01186  1D-myo-inositol 4-phosphate phosphohydrolase
R01187  1D-myo-inositol 3-phosphate phosphohydrolase
R03013  L-histidinol-phosphate phosphohydrolase
R07674  beta-L-galactose-1-phosphate phosphohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00053 Ascorbate and aldarate metabolism
    K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
   00562 Inositol phosphate metabolism
    K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
  09105 Amino acid metabolism
   00340 Histidine metabolism
    K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.15  histidinol-phosphatase
     K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
    3.1.3.25  inositol-phosphate phosphatase
     K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
    3.1.3.93  L-galactose 1-phosphate phosphatase
     K18649  IMPL2; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
Other DBs
GO: 0008934 0010347 0004401
Genes
ATH: AT4G39120(IMPL2)
ALY: 9304959
CRB: 17879544
CSAT: 104716190 104720823 104729217
EUS: EUTSA_v10025644mg
BRP: 103835143
BNA: 106353357 106361489 106406767
BOE: 106336071
RSZ: 108834826 130498826
THJ: 104807751
CPAP: 110810458
CIT: 102617016
PVY: 116110131
MINC: 123213625
TCC: 18607733
GRA: 105795327
GAB: 108474730
DZI: 111297018
EGR: 104453354
GMX: 100527811
PVU: 137821086
VRA: 106762079
VAR: 108330818
VUN: 114163228
VUM: 124824591
CCAJ: 109788874
APRC: 113864744
MTR: 11419457
TPRA: 123899510
CAM: 101502853
PSAT: 127083375
LJA: 130729128
LANG: 109327793
FVE: 101290997
AANS: 126783890
RCN: 112173712
PPER: 18768639
PMUM: 103335696
PAVI: 110768479
PDUL: 117637438
MSYL: 126623914
ZJU: 107426610
MNT: 21384156
CSAV: 115695844
CSV: 101205614
CMO: 103499699
BHJ: 120087575
MCHA: 111015418
CMAX: 111484263
CMOS: 111448992
CPEP: 111777092
RCU: 8284328
MEAN: 126683119
JCU: 105630124
HBR: 110657808
MESC: 110613017
POP: 7464008
PALZ: 118058937
PNZ: 133680276
CILL: 122314369
CAVE: 132184145
QSU: 112020757
QLO: 115969608
VVI: 100260677
VRI: 117909421
SLY: 101254644
CANN: 107840437
INI: 109162162
ITR: 116015736
SIND: 105169672
EGT: 105957671
SMIL: 131005402
SHIS: 125187025
APAN: 127258756
HAN: 110929164
ECAD: 122599474
LSV: 111918256
CCAV: 112501301
CSIN: 114267151
AEW: 130779094
SOE: 110792578
ATRI: 130823150
MOF: 131156480
NNU: 104595613
PSOM: 113308035
OSA: 4342620
OBR: 102719163
OGL: 127778364
BDI: 100838580
ATS: 109768500
TUA: 125543533
LPER: 127342405
LRD: 124665501
SBI: 8085818
ZMA: 100280816
MFLO: 136458031
SITA: 101782298
SVS: 117854542
PVIR: 120706421
PHAI: 112894336
PDA: 103711558
EGU: 105058778
DCT: 110107577
PEQ: 110031830
MSIN: 131237920
ACAK: 137941116
NCOL: 116246642
ATR: 18426768
CJF: 131056799
APRO: F751_5675
 » show all
Reference
  Authors
Torabinejad J, Donahue JL, Gunesekera BN, Allen-Daniels MJ, Gillaspy GE
  Title
VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.
  Journal
Plant Physiol 150:951-61 (2009)
DOI:10.1104/pp.108.135129
  Sequence
[ath:AT4G39120]
Reference
  Authors
Petersen LN, Marineo S, Mandala S, Davids F, Sewell BT, Ingle RA
  Title
The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase.
  Journal
Plant Physiol 152:1186-96 (2010)
DOI:10.1104/pp.109.150805
  Sequence
[ath:AT4G39120]
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