KEGG   ORTHOLOGY: K18057
Entry
K18057                      KO                                     
Symbol
pntD, penD, ptlD
Name
pentalenolactone F synthase [EC:1.14.11.36]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Reaction
R10145  pentalenolactone-D,2-oxoglutarate:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K18057  pntD, penD, ptlD; pentalenolactone F synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.36  pentalenolactone F synthase
     K18057  pntD, penD, ptlD; pentalenolactone F synthase
Other DBs
COG: COG2175
Genes
SMA: SAVERM_2995(ptlD)
SBH: SBI_09677
SCI: B446_29685
SCW: TU94_27395
SLE: sle_13180(sle_13180)
SSIA: A7J05_09250
SGJ: IAG43_27145
SHK: J2N69_35815
Reference
PMID:21250661
  Authors
Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE
  Title
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
  Journal
Biochemistry 50:1739-54 (2011)
DOI:10.1021/bi1019786
  Sequence
[sma:SAVERM_2995]
LinkDB

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