KEGG   ORTHOLOGY: K11533
Entry
K11533                      KO                                     
Symbol
fas
Name
fatty acid synthase, bacteria type [EC:2.3.1.-]
Pathway
map00061  Fatty acid biosynthesis
map00074  Mycolic acid biosynthesis
map01100  Metabolic pathways
map01212  Fatty acid metabolism
map04931  Insulin resistance
Module
M00082  Fatty acid biosynthesis, initiation
M00083  Fatty acid biosynthesis, elongation
Reaction
R01624  acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase
R01626  malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase
R04355  acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04428  (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase
R04429  butyryl-[acp]:NAD+ trans-2-oxidoreductase
R04533  (3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase
R04534  (3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04535  (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] hydro-lyase
R04536  (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04537  (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase
R04543  (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04544  (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase
R04566  (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04568  (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] hydro-lyase
R04724  dodecanoyl-[acp]:NAD+ trans-2-oxidoreductase
R04726  dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04952  butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04953  (3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04954  (3R)-3-hydroxyhexanoyl-[acyl-carrier-protein] hydro-lyase
R04955  hexanoyl-[acp]:NAD+ trans-2-oxidoreductase
R04957  hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04958  octanoyl-[acp]:NAD+ trans-2-oxidoreductase
R04960  octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04961  decanoyl-[acp]:NAD+ trans-2-oxidoreductase
R04963  decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04964  (3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04965  (3R)-3-hydroxydodecanoyl-[acyl-carrier-protein] hydro-lyase
R04966  tetradecanoyl-[acp]:NAD+ trans-2-oxidoreductase
R04968  tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04969  hexadecanoyl-[acp]:NAD+ trans-2-oxidoreductase
R07762  
R07763  
R07764  
R07765  octadecanoyl-[acp]:NAD+ trans-2-oxidoreductase
R10700  palmitoyl-[acp]:CoA S-palmitoyltransferase
R12328  acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, NADH)
R13255  acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, NADH, very-long-chain acyl-CoA forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K11533  fas; fatty acid synthase, bacteria type
   00074 Mycolic acid biosynthesis
    K11533  fas; fatty acid synthase, bacteria type
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K11533  fas; fatty acid synthase, bacteria type
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K11533  fas; fatty acid synthase, bacteria type
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Bacteria type
   K11533  fas; fatty acid synthase, bacteria type
Genes
MTU: Rv2524c(fas)
MTV: RVBD_2524c
MTC: MT2600
MRA: MRA_2551(fas)
MTF: TBFG_12545
MTB: TBMG_01448
MTK: TBSG_01459
MTZ: TBXG_001435
MTE: CCDC5079_2326
MTUR: CFBS_2674(fas)
MTL: CCDC5180_2298
MTO: MTCTRI2_2572(fas)
MTD: UDA_2524c(fas)
MTN: ERDMAN_2777(fas)
MTUB: MT7199_2555
MTX: M943_13040
MTUL: TBHG_02460
MTUT: HKBT1_2665(fas)
MTUU: HKBT2_2668(fas)
MTQ: HKBS1_2672(fas)
MBO: BQ2027_MB2553C(fas)
MBB: BCG_2545c(fas)
MBT: JTY_2539(fas)
MBM: BCGMEX_2537c(fas)
MBK: K60_026230
MBX: BCGT_2363
MAF: MAF_25390(fas)
MMIC: RN08_2799
MCE: MCAN_25641(fas)
MCQ: BN44_50519(fas)
MCV: BN43_40191(fas)
MCX: BN42_40482(fas)
MCZ: BN45_50912(fas)
MORY: MO_002647(fas)
MLE: ML1191(fas)
MLB: MLBr01191(fas)
MPA: MAP_2332c(fas)
MAO: MAP4_1491
MAVU: RE97_07400
MAV: MAV_1650
MIT: OCO_17170
MIA: OCU_17370
MID: MIP_02372
MYO: OEM_15160
MCHI: AN480_08440
MIR: OCQ_14840
MMAL: CKJ54_07300
MLP: MLM_2853
MMAN: MMAN_24520(fas)
MSER: MTY59_34090(fas)
MSA: Mycsm_04419
MUL: MUL_3818(fas)
MMI: MMAR_3962(fas)
MMAE: MMARE11_37690(fas)
MLI: MULP_04134(fas)
MPSE: MPSD_39500(fas)
MSHO: MSHO_61550(fas)
MMC: Mmcs_3648
MKM: Mkms_3721
MJL: Mjls_3661
MMM: W7S_07255
MKN: MKAN_05770
MYV: G155_20325
MYE: AB431_21215
MDX: BTO20_10955
MSHG: MSG_03547(fas)
MFJ: MFLOJ_51490(fas)
MSTO: MSTO_55650(fas)
MSIM: MSIM_40990(fas)
MSAK: MSAS_18070
MKU: I2456_18640
MLW: MJO58_19460
MXE: MYXE_17540(fas)
MNV: MNVI_02360(fas)
MPAG: C0J29_21600
MNM: MNVM_05030
MGOR: H0P51_19580
MCOO: MCOO_15840(fas)
MBAI: MB901379_03439(kasA_2)
MSEO: MSEO_23350(fas)
MHEK: JMUB5695_01835(fas)
MGAU: MGALJ_24890
MLJ: MLAC_10670(fas)
MBRD: MBRA_32960(fas)
MSHJ: MSHI_05970(fas)
MMAM: K3U93_16795
MSPG: F6B93_15935
MOT: LTS72_05450
MLM: MLPF_1627(fas)
MPAA: MKK62_07985
MMEH: M5I08_10805
MKY: IWGMT90018_41140
MADI: A7U43_11590
MWU: PT015_08960
MYW: BVC93_20165
MSM: MSMEG_4757
MSG: MSMEI_4637
MSB: LJ00_23535
MSN: LI99_23540
MSH: LI98_23545
MVA: Mvan_4125
MGI: Mflv_2532
MSP: Mspyr1_19590
MCB: Mycch_3556
MNE: D174_19850
MYN: MyAD_19470
MFT: XA26_41460
MPHL: MPHLCCUG_03687
MVQ: MYVA_3919
MRH: MycrhN_4068
MTHN: 4412656_02980(kasA_2)
MHAS: MHAS_01083(fabY)
MDU: MDUV_05530
MCHT: MCHIJ_29780
MDR: MDOR_26910
MAUU: NCTC10437_03858
MMAG: MMAD_38630
MMOR: MMOR_24470
MFX: MFAL_01750
MAIC: MAIC_37410
MIJ: MINS_34820
MALV: MALV_53740
MTY: MTOK_00180
MPSC: MPSYJ_26890
MARZ: MARA_58700
MGAD: MGAD_57690
MHEV: MHEL_04440
MSAR: MSAR_47830
MANY: MANY_21770
MAUB: MAUB_47620
MPOF: MPOR_42450
MPHU: MPHO_21450
MMUC: C1S78_007580
MMAT: MMAGJ_00290
MBOK: MBOE_32350
MFG: K6L26_11430
MSEI: MSEDJ_49980
MFLV: NCTC10271_01616(kasB_1)
MCEE: MCEL_00680
MBRM: L2Z93_001063
MMON: EWR22_18830
MGO: AFA91_16775
MHOL: K3U96_08855
MSEN: K3U95_09645
MPAE: K0O64_20780
MRF: MJO55_18620
MDF: K0O62_20285
MCRO: MI149_21355
MGRO: FZ046_24000
MAUS: JN090_20105
MFRE: EXE63_24635
MKR: MKOR_02550
MPAK: MIU77_05505
MAB: MAB_1512
MMV: MYCMA_0826
MABB: MASS_1505
MABL: MMASJCM_1531
MCHE: BB28_07545
MIZ: BAB75_08170
MSTE: MSTE_01495
MSAO: MYCSP_06750
MSAL: DSM43276_01368
MJD: JDM601_1383(fas)
MTER: 4434518_01274(fas)
MMIN: MMIN_29470
MHIB: MHIB_08370
MHER: K3U94_07540
MVM: MJO54_07490
ASD: AS9A_3620
CGL: Cgl0836(Cgl0836) Cgl2495(Cgl2495)
CGB: cg0957(fas-IB) cg2743(fas-IA)
CGU: WA5_0802(Fas-IB) WA5_2409(Fas-IA)
CGT: cgR_0950 cgR_2406
CGS: C624_05095 C624_12265
CGG: C629_05095 C629_12270
CGM: cgp_0957 cgp_2743(fas-IA)
CGJ: AR0_04735 AR0_11995
CGQ: CGLAR1_04595
CGX: SB89_04430 SB89_11670
CEF: CE0913(fasA) CE2392(fasB)
CDI: DIP1846(fas)
CDP: CD241_1752(fas)
CDH: CDB402_1711(fas)
CDT: CDHC01_1755(fas)
CDE: CDHC02_1751(fas)
CDR: CDHC03_1732(fas)
CDA: CDHC04_1727(fas)
CDZ: CD31A_1844(fas)
CDB: CDBH8_1814(fas)
CDS: CDC7B_1806(fas)
CDD: CDCE8392_1718(fas)
CDW: CDPW8_1818(fas)
CDV: CDVA01_1693(fas)
CDIP: ERS451417_01845(fas)
CAR: cauri_0280(fas-IB) cauri_2079(fas-IA)
CPU: CPFRC_08285
CPL: Cp3995_1688(fas)
CPG: CP316_08405
CPP: CpP54B96_1673(fas)
CPK: CP1002_04860
CPQ: CPC231_08285
CPX: CPI19_03235
CPZ: CpPAT10_1646(fas)
COR: Cp267_1711(fas)
COP: CP31_08625
COS: Cp4202_1635(fas)
COI: CPCIP5297_08415
COE: CP258_08415
COU: CP162_08395
CPSE: CPTA_00016
CPSU: CPTB_01511
CUL: CULC22_01819(fas)
CUC: CULC809_01720(fas)
CUE: CULC0102_1860(fas)
CUN: Cul210932_1825(fas)
CUQ: Cul210931_1722(fas)
CUZ: Cul05146_1813(fas)
CUJ: CUL131002_1750c(fas)
CUS: CulFRC11_1723(fas)
CVA: CVAR_2516(fas)
CHN: A605_11525
CCN: H924_04030 H924_10500
CTER: A606_10715
CMD: B841_02010 B841_10625
CAZ: CARG_01600
CFN: CFAL_07210
CCG: CCASEI_02190 CCASEI_11355
CVT: B843_03170 B843_10505
CGY: CGLY_02520(fasA)
CII: CIMIT_02655
COA: DR71_1675
CDO: CDOO_02300
CHM: B842_10495
CSX: CSING_01630(fas-IB) CSING_10745(fas-IA)
CMQ: B840_01450 B840_10190(fasB)
CKU: UL82_03150(fas) UL82_09180
CCJ: UL81_01235 UL81_09140
CMV: CMUST_12370
CEI: CEPID_09975(fasB)
CTED: CTEST_01520 CTEST_10665
CUT: CUTER_07030
CLW: CLAC_03175
CDX: CDES_04215 CDES_11295
CSP: WM42_1080 WM42_1933
CSTA: CSTAT_01880 CSTAT_10650
CCJZ: ccrud_04120 ccrud_11215
CFK: CFRA_01480
CPHO: CPHO_01550 CPHO_02950
CFC: CFLV_01700 CFLV_10070
CGV: CGLAU_02710(eryA)
CSTR: CBE89_03485 CBE89_12165
CAQU: CAQU_09750
CSPH: CSPHI_03040
CAMG: CAMM_01925 CAMM_10480
CMIN: NCTC10288_00485(fas-IA) NCTC10288_02249(fas-IB)
CPEG: CPELA_02550(kasB)
CXE: FOB82_08515
CEE: CENDO_01490 CENDO_09050(kasB)
CSAN: E3227_01635
CGK: CGERO_08470(kasB)
CRF: FRC0190_01874
CRL: NCTC7448_00314(fasB) NCTC7448_01123(kasB)
CCHO: CCHOA_10625(fabF)
CPRE: Csp1_04230(fabY)
CPSO: CPPEL_02435(fabF)
CSUR: N24_0954(fasA) N24_2568(fasB)
CCYS: SAMEA4530656_0333(kasB) SAMEA4530656_2195(pksC)
CMAT: HBA49_03730 HBA49_10140
CYZ: C3B44_01315 C3B44_09445
CANS: GP473_05930
CLIA: C3E79_02625
CPRP: I6I69_04065
CAMC: I6I65_10470
CGLU: I6J20_04790
CLIZ: G7Y31_01330 G7Y31_09860
CSIL: CBE74_09365
CQN: G7Y29_02400
CKW: CKALI_02715(kasB)
CCOE: CETAM_01810(eryA) CETAM_10810(kasB)
COK: COCCU_11165(kasB)
CORY: FQV43_07980
CPOY: GP475_09750
CFY: I6L56_11760
CHIN: J5O04_11395
CPSP: L9H27_09175
CMAS: CMASS_08310
CIHU: CIHUM_02450(ppsA1)
CCOY: CCOY_02580(ppsA1)
CHAD: CHAD_02785(fabD)
CFG: CFREI_01060(fabF1) CFREI_11110(fabF2)
CCAW: CCANI_01045(fabF1) CCANI_11235(fabF2)
CAUI: CAURIS_02690(pksC)
CFAC: CFAEC_03700(fabF) CFAEC_10920(kasB)
CFEU: CFELI_08605(fabF) CFELI_11195
CAUS: CAURIC_07115(fabF)
CATR: CATRI_01505(eryA) CATRI_10160(kasB)
CDUR: CDUR_01425(fabF) CDUR_10630(fabD)
CCOU: CCONF_01335 CCONF_09300(kasB)
CHAN: CHAN_03160(kasB)
CGF: CGUA_01910(eryA)
CGOI: CGOTT_02660(fabD)
CBRE: QP027_00925 QP027_08970
CRIE: AK829_07420
CIK: H0194_03470 H0194_06905
BFV: C628_04630 C628_12140
NFA: NFA_12570
NFR: ERS450000_02852(kasA_2)
NCY: NOCYR_1266
NBR: O3I_007715
NNO: NONO_c62310
NSL: BOX37_06080
NSR: NS506_02387
NTP: CRH09_08550
NOZ: DMB37_28650
NOD: FOH10_23960
NAH: F5544_09215 F5544_18475
NAD: NCTC11293_02130(kasA_3)
NWL: NWFMUON74_56920
NIE: KV110_08360
NTC: KHQ06_36770
NHU: H0264_35910
NYA: LTV02_37320
NGP: LTT66_05205
NSPU: IFM12276_50100
NYU: D7D52_33285
RHA: RHA1_ro01426
RER: RER_38730(fas1)
REY: O5Y_17935
REB: XU06_18130
RQI: C1M55_19195
ROP: ROP_11350(fas1)
ROA: Pd630_LPD05549
RPY: Y013_00225
RBY: CEJ39_10815
RHB: NY08_300
RAV: AAT18_10435
RRZ: CS378_00175
RHU: A3Q40_00856(fabF)
RHQ: IM25_14175
RHOD: AOT96_29825
RRT: 4535765_01743(fabF_1)
RCR: NCTC10994_01125(fabF_2)
RTM: G4H71_02270
RKO: JWS14_07340
RGO: KYT97_26545
ROZ: CBI38_10845
RPSK: JWS13_38845
RGOR: NMQ04_07670
RHOP: D8W71_21340
RHOO: RA302_18705
RHOU: KZJ41_11620
RHOW: A4U64_14210
RHOJ: JVH1_30225
RHOS: QWW67_00195
RHOQ: QWW98_00195
RHOY: QNA09_07955
RHOH: CPI83_10850
RFA: A3L23_03591(fabF_2)
RHS: A3Q41_04635(fabF_2)
REQ: REQ_30820
PSOW: ABI214_23000
WHR: OG579_00225
GBR: Gbro_1994
GPO: GPOL_c18930
GOR: KTR9_1925
GOQ: ACH46_07590
GTA: BCM27_10340
GIT: C6V83_08095
GRU: GCWB2_09690
GOM: D7316_00507(fabY)
GAV: C5O27_18065
GOD: GKZ92_09295
GOS: QAD21_09575
GOJ: GR168_09375
GAM: GII34_08965
GPD: GII33_08370
GJI: H1R19_09580
GOI: LK459_00735
GHN: MVF96_09730
GAMI: IHQ52_12580
GMG: NWF22_20045
GSI: P5P27_06160
SPIN: KV203_05260
TPR: Tpau_1315
TSM: ASU32_07435
TPUL: TPB0596_32700
SRT: Srot_2540
DTM: BJL86_1142
DIT: C3V38_11140
DIZ: CT688_05105
DPC: A6048_05175
DLU: A6035_05360
DKN: NHB83_04930
DCD: VYL96_05265
TOY: FO059_13250
NBE: Back2_21680
AER: AERYTH_04330
AEZ: C3E78_05185
AEB: C6I20_03905
AEF: GEV26_05000
ASEZ: H9L21_12345
ADB: NP095_12315
AWN: NQV15_05190
MUZ: H4N58_17145
NBT: KLP28_14995
ARCA: HC352_06225
AWL: P8A24_02740
ACAS: P7079_02415
TPY: CQ11_04125
TPYO: X956_03665
TBW: NCTC13354_01643(pksC)
TPEC: HLG82_02770
TBER: QPC17_02525
ASG: FB03_03380
AUU: CJ184_005205
ATIM: CYJ17_0008170
AMY: ADJ76_03970
SOO: FBF35_04415
ACQ: AM609_06765
AOS: AXE84_10965
ARD: AXF14_10590
ACTP: B6G06_04410
ACTC: CHIBA101_1279
ACTO: C3V41_03485
ANE: ATCC27039_09690(fas)
ACTZ: CWT12_05690
AIR: NCTC12972_00819(fabF)
ASLA: NCTC11923_01936(fabF_1)
AVC: NCTC10951_00774(fabF)
AWE: JG540_05165
AMAM: HPC72_05310
AREP: ID810_06125
AGH: M3I41_04430
AMAS: QU670_08650
ACAP: MANAM107_24180(fas)
AUO: R3I39_08520
ACTH: JJJ15_00855
ACHN: JJJ14_06500
AVU: BK816_05920
FSL: EJO69_07570
FLH: EJ997_08745
WNE: PIG85_07465
GHM: CJ187_008950
BLO: BL1537(fas)
BLJ: BLD_1633(fabD)
BLN: Blon_2284
BLON: BLIJ_2357
BLF: BLIF_1803
BLL: BLJ_1807
BLB: BBMN68_1558(fabD)
BLM: BLLJ_1730
BLK: BLNIAS_00207(fabD)
BLZ: BLGT_09300
BLX: GS08_09385
BAD: BAD_0256(fas)
BADL: BADO_0264
BADO: BBMN23_0284
BLA: BLA_0302(fas)
BLC: Balac_0317
BLT: Balat_0317
BBB: BIF_00783
BBC: BLC1_0304
BNM: BALAC2494_00812
BLV: BalV_0307
BLW: W7Y_0318
BLS: W91_0328
BANI: BL12_01595
BANL: BLAC_01595
BNI: BANAN_01650
BANM: EN10_01610
BDE: BDP_0362(fas)
BDN: BBDE_0344
BBP: BBPR_1638(fas)
BBI: BBIF_1579(fas)
BBF: BBB_1614(fas)
BBV: HMPREF9228_1796
BBRU: Bbr_1719(fas)
BBRE: B12L_1649
BBRV: B689b_1747
BBRJ: B7017_1913
BBRC: B7019_1885
BBRN: B2258_1739
BBRS: BS27_1711(fas)
BBRD: BBBR_1720
BAST: BAST_1439
BTP: D805_1518
BKA: AH68_01470
BKS: BBKW_0274
BCAT: BBCT_0239
BPSP: AH67_01700
BANG: BBAG_0159
BPSC: BBPC_0268
BSCA: BBSC_0379
BACT: AB656_06625
BCHO: BcFMB_03960
BGX: ESN35_09340
BEU: BE0216_08970
BSUE: BS3272_09210
BFJ: B19861_02540
GVG: HMPREF0421_21228
GVA: HMPREF0424_1197
GVH: HMPREF9231_0305
GPT: K9E43_02340
GSW: K9E37_02390
SIJ: SCIP_0276
PDO: PSDT_1228
BAPK: KIMH_13920(fas)
BNK: KIM372_02220(fas)
DHI: LH044_07785
UAM: UABAM_01823
 » show all
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