| Entry |
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| Symbol |
PCCA, pccA
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| Name |
propionyl-CoA carboxylase alpha subunit [EC: 6.4.1.3]
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| Pathway |
| map00280 | Valine, leucine and isoleucine degradation |
| map00630 | Glyoxylate and dicarboxylate metabolism |
| map01110 | Biosynthesis of secondary metabolites |
| map01120 | Microbial metabolism in diverse environments |
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| Module |
| M00741 | Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA |
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| Reaction |
| R01859 | propanoyl-CoA:carbon-dioxide ligase (ADP-forming) |
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| Disease |
| H01400 | Secondary hyperammonemia |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
K01965 PCCA, pccA; propionyl-CoA carboxylase alpha subunit
00640 Propanoate metabolism
K01965 PCCA, pccA; propionyl-CoA carboxylase alpha subunit
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K01965 PCCA, pccA; propionyl-CoA carboxylase alpha subunit
Enzymes [BR:ko01000]
6. Ligases
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.3 propionyl-CoA carboxylase
K01965 PCCA, pccA; propionyl-CoA carboxylase alpha subunit
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Stankovics J, Ledley FD |
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| Title |
Cloning of functional alpha propionyl CoA carboxylase and correction of enzyme deficiency in pccA fibroblasts. |
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| Journal |
Am J Hum Genet 52:144-51 (1993) |
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| Sequence |
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| Reference |
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| Authors |
Huang CS, Sadre-Bazzaz K, Shen Y, Deng B, Zhou ZH, Tong L |
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| Title |
Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. |
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| Journal |
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| Sequence |
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| LinkDB |
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