Entry
Symbol
hpaE, hpcC
Name
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:
1.2.1.60 ]
Pathway
map01120 Microbial metabolism in diverse environments
map01220 Degradation of aromatic compounds
Module
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
Reaction
R04418 5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
K00151 hpaE, hpcC; 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
K00151 hpaE, hpcC; 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
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Reference
Authors
Roper DI, Stringfellow JM, Cooper RA
Title
Sequence of the hpcC and hpcG genes of the meta-fission homoprotocatechuic acid pathway of Escherichia coli C: nearly 40% amino-acid identity with the analogous enzymes of the catechol pathway.
Journal
Sequence
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