KEGG   GLYCAN: G00016
Entry
G00016                      Glycan                                 
Name
Core fucose
Composition
(GlcNAc)4 (LFuc)1 (Man)3 (Asn)1
Mass
1445.4 (Asn)
Structure
Comment
Tumor marker: AFP-L3 (fucosylated AFP)
Reaction
Pathway
map00510  N-Glycan biosynthesis
map00513  Various types of N-glycan biosynthesis
map01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Enzyme
2.4.1.38        2.4.1.68
Brite
Cancer-associated carbohydrates [br08441.html]
 N-glycan
  G00016
Reference
1  [PMID:7592613]
  Authors
Dell A, Morris HR, Easton RL, Panico M, Patankar M, Oehniger S, Koistinen R, Koistinen H, Seppala M, Clark GF.
  Title
Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities.
  Journal
J Biol Chem 270:24116-26 (1995)
DOI:10.1074/jbc.270.41.24116
Reference
2  [PMID:11343276]
  Authors
Mandal TK, Mukhopadhyay C.
  Title
Effect of glycosylation on structure and dynamics of MHC class I glycoprotein: a molecular dynamics study.
  Journal
Reference
3  [PMID:12199704]
  Authors
Ikeda K, Yonezawa N, Naoi K, Katsumata T, Hamano S, Nakano M.
  Title
Localization of N-linked carbohydrate chains in glycoprotein ZPA of the bovine egg zona pellucida.
  Journal
Eur J Biochem 269:4257-66 (2002)
DOI:10.1046/j.1432-1033.2002.03111.x
Reference
4  [PMID:12485595]
  Authors
Kotra LP, Zhang L, Fridman R, Orlando R, Mobashery S.
  Title
N-Glycosylation pattern of the zymogenic form of human matrix metalloproteinase-9.
  Journal
Bioorg Chem 30:356-70 (2002)
DOI:10.1016/S0045-2068(02)00501-1
Reference
5  [PMID:14559815]
  Authors
Noda K, Miyoshi E, Gu J, Gao CX, Nakahara S, Kitada T, Honke K, Suzuki K, Yoshihara H, Yoshikawa K, Kawano K, Tonetti M, Kasahara A, Hori M, Hayashi N, Taniguchi N.
  Title
Relationship between elevated FX expression and increased production of GDP-L-fucose, a common donor substrate for fucosylation in human hepatocellular carcinoma and hepatoma cell lines.
  Journal
Cancer Res 63:6282-9 (2003)
Other DBs
LinkDB
KCF data

NODE        9
            1   Asn        23     0
            2   GlcNAc     15     0
            3   LFuc       11     6
            4   GlcNAc      5     0
            5   Man        -4     0
            6   Man       -12     4
            7   Man       -12    -4
            8   GlcNAc    -21     4
            9   GlcNAc    -21    -4
EDGE        8
            1     2:b1    1    
            2     3:a1    2:6  
            3     4:b1    2:4  
            4     5:b1    4:4  
            5     6:a1    5:6  
            6     7:a1    5:3  
            7     8:b1    6:2  
            8     9:b1    7:2

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