KEGG   DGROUP: CYP2C8 substrate
Entry
DG02918                     DGroup                                 
Name
CYP2C8 substrate
Type
Metabolism
Member
Loperamide
 D08144  
Loperamide (INN)
 D00729  
Loperamide hydrochloride (JAN/USP)  <JP/US>
 D07113  
Loperamide oxide (INN)
D09848  
Pioglitazone hydrochloride and glimepiride tablets (JP18)  <JP/US>
Pioglitazone
 D08378  
Pioglitazone (INN)
 D00945  
Pioglitazone hydrochloride (JP18/USP)  <JP/US>
D00594  
Repaglinide (JAN/USP/INN)  <JP/US>
Retinol (vit A)
 D06543  
Vitamin A (USP)  <JP>
 D00164  
Retinol palmitate (JP18)  <JP/US>
 D01621  
Retinol acetate (JP18)
 D08477  
Retinol propionate
Treprostinil
 D06213  
Treprostinil (JAN/USAN/INN)  <JP/US>
 D08628  
Treprostinil monosodium salt
 D10430  
Treprostinil diolamine (USAN)  <US>
 D12005  
Treprostinil palmitil (USAN/INN)
 D12629  
Treprostinil phosphate (USAN)
D09994  
Selexipag (JAN/USAN/INN)  <JP/US>
D10593  
Roxadustat (JAN/USAN/INN)  <JP>
D09572  
Riociguat (JAN/USAN/INN)  <JP/US>
D12963  
Macitentan and tadalafil  <JP/US>
Torasemide
 D00382  
Torsemide (USP); Torasemide (JAN/INN)  <JP/US>
 D08619  
Torasemide sodium
D10633  
Finerenone (JAN/USAN/INN)  <JP/US>
Cerivastatin
 D07661  
Cerivastatin (INN)
 D00889  
Cerivastatin sodium (JAN/USAN)
D10711  
Pemafibrate (JAN)  <JP>
Terbinafine
 D02375  
Terbinafine (USAN/INN)
 D02219  
Terbinafine hydrochloride (JP18/USP)  <JP/US>
D12137  
Elagolix, estradiol and norethisterone  <US>
D11000  
Vamorolone (USAN/INN)  <US>
D10582  
Dasabuvir, ombitasvir, paritaprevir and ritonavir
D10827  
Sofosbuvir and velpatasvir  <JP/US>
Cyclophosphamide
 D07760  
Cyclophosphamide (INN)
 D00287  
Cyclophosphamide (USP); Cyclophosphamide hydrate (JP18)  <JP/US>
Nilotinib
 D08953  
Nilotinib (USAN/INN)
 D06413  
Nilotinib hydrochloride hydrate (JAN)  <JP/US>
 D12444  
Nilotinib hydrochloride dihydrate (JAN)
 D12854  
Nilotinib laurylsulfate (USAN)
 D13008  
Nilotinib tartaric acid (USAN)
Dabrafenib
 D10064  
Dabrafenib (USAN)
 D10104  
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN)  <JP/US>
Lapatinib
 D08108  
Lapatinib (INN)
 D04024  
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN)  <JP/US>
Tucatinib
 D11141  
Tucatinib (USAN/INN)  <US>
 D12442  
Tucatinib ethanolate (JAN)
Momelotinib
 D10315  
Momelotinib (USAN/INN)
 D10358  
Momelotinib dihydrochloride (USAN)
 D10889  
Momelotinib hydrochloride hydrate (JAN)  <JP/US>
D11977  
Fruquintinib (JAN/USAN)  <JP/US>
Tepotinib
 D11717  
Tepotinib (USAN/INN)
 D11073  
Tepotinib hydrochloride (USAN); Tepotinib hydrochloride hydrate (JAN)  <JP/US>
Vorasidenib
 D11834  
Vorasidenib (USAN/INN)
 D11835  
Vorasidenib citrate (USAN); Vorasidenib citric acid hydrate (JAN)  <US>
D10218  
Enzalutamide (JAN/USAN)  <JP/US>
D11040  
Apalutamide (JAN/INN)  <JP/US>
Etrasimod
 D10930  
Etrasimod (USAN)
 D10931  
Etrasimod arginine (USAN); Etrasimod L-arginine (JAN)  <US>
Iptacopan
 D12251  
Iptacopan (USAN/INN)
 D12252  
Iptacopan hydrochloride (USAN); Iptacopan hydrochloride hydrate (JAN)  <JP/US>
D09365  
Palovarotene (JAN/USAN/INN)  <US>
D01372  
Zopiclone (JP18/INN)  <JP>
Vortioxetine
 D10184  
Vortioxetine (USAN)
 D10185  
Vortioxetine hydrobromide (JAN/USAN)  <JP/US>
 D12544  
Vortioxetine hemihydrobromide (USAN)
D10964  
Omaveloxolone (USAN/INN)  <US>
Methadone
 D08195  
Methadone (BAN)
 D02102  
Methadone hydrochloride (JAN/USP)  <JP/US>
Hydroxychloroquine
 D08050  
Hydroxychloroquine (INN)
 D02114  
Hydroxychloroquine sulfate (JAN/USP)  <JP/US>
Amodiaquine
 D02922  
Amodiaquine (USP/INN)
 D02466  
Amodiaquine hydrochloride (USP)
Olodaterol
 D10145  
Olodaterol (USAN/INN)
 D10020  
Olodaterol hydrochloride (JAN/USAN)  <US>
Montelukast
 D08229  
Montelukast (INN)
 D00529  
Montelukast sodium (JP18/USP)  <JP/US>
D10512  
Brinzolamide and timolol maleate  <JP>
Paclitaxel
 D00491  
Paclitaxel (JAN/USP/INN)  <JP/US>
 D05333  
Paclitaxel poliglumex (USAN/INN)
D00069  
Vitamin A oil (JP18)  <JP>
D01855  
Mozavaptane hydrochloride (JAN)
 » expand
Class
Metabolizing enzyme substrate
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