Entry |
|
Name |
Sunvozertinib (USAN/INN) |
Formula |
C29H35ClFN7O3
|
Exact mass |
583.2474
|
Mol weight |
584.08
|
Structure |
|
Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03162 EGFR inhibitor
|
Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
Comment |
Treatment of non-small cell lung cancer
|
Target |
|
Pathway |
|
Interaction |
|
Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03162 EGFR inhibitor
D12506 Sunvozertinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
EGFR family
EGFR* [HSA_VAR:1956v2]
D12506 Sunvozertinib (USAN/INN)
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 41
1 C8y C 20.7991 -20.5153
2 N5x N 20.7991 -21.9157
3 C8y C 21.9894 -22.6159
4 N5x N 23.2498 -21.9157
5 C8x C 23.2498 -20.5153
6 C8x C 21.9894 -19.8151
7 N1b N 21.9722 -24.0162
8 C8y C 23.1889 -24.7389
9 C8x C 23.1718 -26.1169
10 C8y C 24.3758 -26.8321
11 C8y C 25.5972 -26.1471
12 C8x C 25.6143 -24.7691
13 C8y C 24.4104 -24.0538
14 N1b N 19.5834 -19.8200
15 C8y C 18.3947 -20.5130
16 C8y C 17.1980 -19.8286
17 C8x C 15.9880 -20.5337
18 C8y C 15.9937 -21.9341
19 C8y C 17.1904 -22.6185
20 C8x C 18.4003 -21.9134
21 X F 14.7728 -22.6459
22 C1d C 17.1920 -18.4152
23 O1a O 17.1920 -17.0148
24 C1a C 15.8616 -18.4152
25 C1a C 18.6624 -18.4152
26 X Cl 17.1959 -24.0158
27 O2a O 24.4281 -22.6860
28 C1a C 25.6589 -21.9964
29 N1b N 24.3585 -28.2175
30 C5a C 23.1458 -28.8975
31 O5a O 23.1977 -30.3171
32 N1y N 26.8117 -26.8690
33 C1x C 26.9420 -28.2822
34 C1y C 28.3263 -28.5951
35 C1x C 29.0516 -27.3751
36 C1x C 28.1155 -26.3084
37 N1c N 28.8750 -29.8703
38 C1a C 30.2453 -30.0322
39 C1a C 28.0159 -31.0219
40 C2b C 21.9591 -28.2313
41 C2a C 20.7834 -28.9292
BOND 44
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 3 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 1 14 1
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 15 20 1
23 18 21 1
24 16 22 1
25 22 23 1
26 22 24 1
27 22 25 1
28 19 26 1
29 13 27 1
30 27 28 1
31 10 29 1
32 29 30 1
33 30 31 2
34 11 32 1
35 32 33 1
36 33 34 1
37 34 35 1
38 35 36 1
39 32 36 1
40 34 37 1 #Up
41 37 38 1
42 37 39 1
43 30 40 1
44 40 41 2
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