Entry |
|
Name |
Mecamylamine hydrochloride (USP); Inversine (TN) |
Product |
|
Generic |
|
Formula |
C11H21N. HCl
|
Exact mass |
203.1441
|
Mol weight |
203.75
|
Structure |
|
Simcomp |
|
Class |
Cardiovascular agent
DG01695 Ganglion-blocking antiadrenergic
|
Remark |
Product (DG00252): | D00611<US> |
|
Efficacy |
Antihypertensive |
Disease |
Essential hypertension [DS: H01633] |
Comment |
Secondary amine
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02B ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
C02BB Secondary and tertiary amines
C02BB01 Mecamylamine
D00611 Mecamylamine hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Cardiovascular Agents, Other
Mecamylamine
D00611 Mecamylamine hydrochloride (USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01695 Ganglion-blocking antiadrenergic
DG00252 Mecamylamine
D00611 Mecamylamine hydrochloride
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN
D00611 Mecamylamine hydrochloride (USP) <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01695 Ganglion-blocking antiadrenergic
DG00252 Mecamylamine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 13
1 C1z C 24.5931 -18.6687
2 C1y C 23.3666 -17.9621
3 C1z C 24.5931 -20.0821
4 C1x C 22.9112 -19.3169
5 C1x C 22.1346 -18.6687
6 C1y C 23.3551 -20.6894
7 C1x C 22.1346 -20.0821
8 C1a C 25.7844 -17.9798
9 C1a C 25.7514 -20.8042
10 C1a C 24.5931 -21.4852
11 N1b N 24.5931 -17.2655
12 C1a C 25.7847 -16.5771
13 X Cl 29.3301 -19.5301
BOND 13
1 1 2 1
2 1 3 1
3 2 4 1
4 2 5 1
5 3 6 1
6 5 7 1
7 4 6 1
8 6 7 1
9 1 8 1
10 3 9 1
11 3 10 1
12 1 11 1
13 11 12 1
|