Entry |
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Name |
2-oxoglutarate decarboxylase;
oxoglutarate decarboxylase;
alpha-ketoglutarate decarboxylase;
alpha-ketoglutaric decarboxylase;
pre-2-oxoglutarate decarboxylase;
2-oxoglutarate carboxy-lyase
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Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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Sysname |
2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)
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Reaction(IUBMB) |
2-oxoglutarate = succinate semialdehyde + CO2 [RN: R00272]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Requires thiamine diphosphate. Highly specific.
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History |
EC 4.1.1.71 created 1989
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Orthology |
K01616 | multifunctional 2-oxoglutarate metabolism enzyme |
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Genes |
MBO: | BQ2027_MB1280C(sucA) |
MBAI: | MB901379_03656(kgd) |
MHEK: | JMUB5695_01618(kgd) |
MPHL: | MPHLCCUG_04016(kgd) |
MAUU: | NCTC10437_04206(kgd) |
MFLV: | NCTC10271_01260(kgd) |
MSAL: | DSM43276_01254(kgd) |
CDIP: | ERS451417_00905(sucA) |
CUN: | Cul210932_0885(odhA) |
CUQ: | Cul210931_0847(odhA) |
CUJ: | CUL131002_0863c(odhA) |
CMIN: | NCTC10288_01533(kgd) |
CCYS: | SAMEA4530656_1418(kgd) |
NFR: | ERS450000_05232(kgd) |
NAD: | NCTC11293_05991(kgd) |
RCR: | NCTC10994_01417(sucA) |
SLE: | sle_24580(sle_24580) |
SGM: | GCM10017557_26170(kgd) |
STUI: | GCM10017668_48040(kgd) |
SXT: | KPP03845_105052(kgd) |
SCYN: | N8I84_26620 N8I84_39270 |
SCAJ: | O1G22_08830 O1G22_14200 |
AGLA: | OIE69_15100 OIE69_36040 |
MSUW: | GCM10025863_13310(kgd) |
FSB: | GCM10025867_33630(kgd) |
AMAU: | DSM26151_09670(kgd) |
AMAV: | GCM10025877_27790(kgd) |
MALK: | MalAC0309_2119(kgd) |
PSEV: | USB125703_01540(kgd) |
GMN: | GMOLON4_1176(kgd) GMOLON4_444(kgd) |
AAGI: | NCTC2676_1_01961(kgd) |
GCR: | GcLGCM259_1015(sucA) |
RDN: | HMPREF0733_10027(sucA) |
DCO: | SAMEA4475696_2236(kgd) |
DSS: | GCM25873_00560 GCM25873_28350 |
PAK: | HMPREF0675_4325(sucA) |
PAV: | TIA2EST22_06270(kgd) |
PAX: | TIA2EST36_06245(kgd) |
PACN: | TIA1EST1_06235(kgd) |
PPC: | HMPREF9154_1400(sucA) |
NAQU: | ENKNEFLB_01828(kgd) |
ARHD: | VSH64_16515 VSH64_29065 |
AMOG: | QRX60_19705 QRX60_30370 |
MSAG: | GCM10017556_14800(kgd) |
ACTR: | Asp14428_58520(kgd) |
MCU: | HMPREF0573_10393(sucA) |
TBW: | NCTC13354_01464(kgd) |
ANE: | ATCC27039_15350(kgd) |
AHW: | NCTC11636_02448(kgd) |
AIR: | NCTC12972_00272(kgd) |
ASLA: | NCTC11923_02436(kgd) |
AVC: | NCTC10951_01404(kgd) |
ACAP: | MANAM107_04180(kgd) |
PLAN: | A1s21148_01145(kgd) |
PLAK: | A1s21155_00950(kgd) |
PLIM: | PHILAsVB114_06035(kgd) |
ABAM: | B1s21122_05265(kgd) |
BALA: | DSM104299_00626(odhA) |
» show all
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Reference |
1 |
Authors |
Shigeoka S, Onishi T, Maeda K, Nakano Y, Kitaoka S. |
Title |
Occurrence of thiamin pyrophosphate-dependent 2-oxoglutarate decarboxylase in mitochondria of Euglena gracilis. |
Journal |
FEBS Lett 195:43-47 (1986) |
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.71 |
ExPASy - ENZYME nomenclature database: | 4.1.1.71 |
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LinkDB |
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