KEGG ENZYME: 3.5.1.89

ENZYME: 3.5.1.89

Entry

EC 3.5.1.89                 Enzyme

Name

N-acetylglucosaminylphosphatidylinositol deacetylase;
N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase;
N-acetylglucosaminylphosphatidylinositol de-N-acetylase;
GlcNAc-PI de-N-acetylase;
GlcNAc-PI deacetylase;
acetylglucosaminylphosphatidylinositol deacetylase

Class

Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides

Sysname

6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase

Reaction(IUBMB)

6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate [RN:R03482 R05917]

Reaction(KEGG)

R03482 R05917(G)

Substrate

6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol [CPD:C01288];
H2O [CPD:C00001]

Product

6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol [CPD:C04248];
acetate [CPD:C00033]

Comment

Involved in the second step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes. The enzyme appears to be composed of a single subunit (PIG-L in mammalian cells and GPI12 in yeast). In some species, the long-chain sn-1-acyl group of the phosphatidyl group is replaced by a long-chain alkyl or alk-1-enyl group.

History

EC 3.5.1.89 created 1992 as EC 3.1.1.69, transferred 2002 to EC 3.5.1.89, modified 2002

Pathway

ec00563

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis

ec01100

Metabolic pathways

Orthology

K03434

N-acetylglucosaminylphosphatidylinositol deacetylase

Genes

HSA:	9487(PIGL)

PTR:	468371(PIGL)

PPS:	100986317(PIGL)

GGO:	101144089(PIGL)

PON:	100450550(PIGL)

PPYG:

129016879(PIGL)

NLE:	100598552(PIGL)

HMH:	116458277(PIGL)

SSYN:

129470742(PIGL)

MCC:	696605(PIGL)

MCF:	102118394(PIGL)

MTHB:

126938821

MNI:	105491090(PIGL)

CSAB:

103242452 103242566

CATY:

105571942(PIGL)

PANU:

101000928(PIGL)

TGE:	112609890(PIGL)

MLEU:

105535990(PIGL)

RRO:	104681437(PIGL)

RBB:	108522160(PIGL)

TFN:	117066420(PIGL)

PTEH:

111526451(PIGL)

CANG:

105523187(PIGL)

CJC:	100415215(PIGL)

SBQ:	101046118(PIGL)

CIMI:

108281293(PIGL)

ANAN:

135275751(PIGL)

CSYR:

103264906(PIGL)

MMUR:

105856336 105861945(PIGL)

LCAT:

123621078(PIGL)

OGA:	100945997(PIGL)

MMU:	327942(Pigl)

MCAL:

110305309(Pigl)

MPAH:

110332470(Pigl)

RNO:	192263(Pigl)

MCOC:

116077207(Pigl)

ANU:	117712012(Pigl)

ASYL:

127693381(Pigl)

MUN:	110549787(Pigl)

CGE:	100752487(Pigl)

MAUA:

101831730(Pigl)

PROB:

127219156(Pigl)

PLEU:

114682966(Pigl)

MORG:

121456054(Pigl)

MFOT:

126514642

AAMP:

119811151(Pigl)

NGI:	103726063(Pigl)

HGL:	101703262(Pigl)

CPOC:

100728121(Pigl)

CCAN:

109692378(Pigl)

DORD:

105985722(Pigl)

DSP:	122103176(Pigl)

PLOP:

125366195(Pigl)

NCAR:

124979066

MMMA:

107160174(Pigl)

OCU:

100339176

OPI:	101535586(PIGL)

TUP:	102486610(PIGL)

GVR:	103588964(PIGL)

CFA:	479514(PIGL)

CLUD:

112647296(PIGL)

VVP:	112924927(PIGL)

VLG:	121499506(PIGL)

NPO:	129497516(PIGL)

AML:	100483189(PIGL)

UMR:	103658516(PIGL)

UAH:	113271260(PIGL)

UAR:	123779778(PIGL)

ELK:

111139474

LLV:

125088139

MPUF:

101678879(PIGL)

MNP:	132004326(PIGL) 132020385

MLK:	131816858(PIGL) 131839717

NVS:	122906799(PIGL)

ORO:	101372356(PIGL)

EJU:	114198221(PIGL)

ZCA:	113939426(PIGL)

MLX:	118000112(PIGL)

NSU:	110584625(PIGL)

LWW:	102730451(PIGL)

FCA:	101095055(PIGL)

PYU:	121015848(PIGL)

PCOO:

112857141(PIGL)

PBG:	122485008(PIGL)

PVIV:

125151676(PIGL)

LRUF:

124519592

PTG:	102950977(PIGL)

PPAD:

109245814(PIGL)

PUC:

125927571

AJU:

106981433

HHV:	120228783(PIGL)

BTA:	507080(PIGL)

BOM:	102267257(PIGL)

BIU:	109573401(PIGL)

BBUB:

102404303(PIGL)

BBIS:

104990685(PIGL)

CHX:	102178568(PIGL)

OAS:	101117518(PIGL)

BTAX:

128065533(PIGL)

CSUM:

138083384(PIGL)

ODA:	120867423(PIGL)

CCAD:

122444738(PIGL)

MREE:

136149138(PIGL)

MBEZ:

129544187(PIGL)

SSC:	100523821(PIGL)

CFR:	102516594(PIGL)

CBAI:

105084047(PIGL)

CDK:	105085083(PIGL)

VPC:	102535781(PIGL)

BACU:

102998131(PIGL)

BMUS:

118886155(PIGL)

LVE:	103077014(PIGL)

OOR:	101287111(PIGL)

DLE:	111167747(PIGL)

PCAD:

102982485(PIGL)

PSIU:

116745446(PIGL)

NASI:

112405209(PIGL)

ECB:	100073146(PIGL)

EPZ:	103543984 103560480(PIGL)

EAI:	106838863(PIGL)

MYB:	102250124(PIGL)

MYD:	102766905(PIGL)

MMYO:

118649376(PIGL)

MLF:	102432985(PIGL)

MDT:	132217966(PIGL)

PKL:	118704684(PIGL)

EFUS:

103299375(PIGL)

MNA:	107524504(PIGL)

DRO:	112308422(PIGL)

SHON:

119002797(PIGL)

AJM:	119064432(PIGL)

PDIC:

114515277(PIGL)

PHAS:

123809297(PIGL)

MMF:	118641249(PIGL)

PPAM:

129068780(PIGL)

HAI:	109382180(PIGL)

RFQ:	117013486(PIGL)

PALE:

102893644(PIGL)

PGIG:

120589818(PIGL)

PVP:	105291300(PIGL)

RAY:	107511059(PIGL)

MJV:	108403992(PIGL)

TOD:	119232476(PIGL)

SARA:

101554683(PIGL)

SFUM:

130044031(PIGL)

SETR:

126013748(PIGL)

LAV:	100674275(PIGL)

TMU:

101359452

ETF:	101650245(PIGL)

DNM:	101427021(PIGL)

MDO:	100021142(PIGL)

GAS:	123244500(PIGL)

SHR:	100914581(PIGL)

AFZ:

127558776

PCW:	110222198(PIGL)

TVP:	118858146(PIGL)

PBRV:

138162436(PIGL)

OAA:	100078091(PIGL)

GGA:	417600(PIGL)

PCOC:

116228023(PIGL)

MGP:	100546427(PIGL)

CJO:	107322415(PIGL)

TPAI:

128083595(PIGL)

LMUT:

125703152(PIGL)

NMEL:

110407644(PIGL)

APLA:

101805021(PIGL)

ACYG:

106045784(PIGL)

CATA:

118255065(PIGL)

AFUL:

116497428(PIGL)

TGU:	100218498(PIGL)

LSR:	110467690(PIGL)

SCAN:

103820311(PIGL)

PMOA:

120507791(PIGL)

OTC:	121345710(PIGL)

PRUF:

121361829(PIGL)

GFR:	102038000(PIGL)

FAB:	101819705(PIGL)

OMA:	130261096(PIGL)

PHI:	102109608(PIGL)

PMAJ:

107212778(PIGL)

CCAE:

111937957(PIGL)

CCW:	104691180(PIGL)

CBRC:

103613422(PIGL)

ACOE:

138120786(PIGL)

ETL:	114061221(PIGL)

ZAB:	102061401(PIGL)

ZLE:	135455893(PIGL)

SVG:	106853276(PIGL)

MMEA:

130576947(PIGL)

HRT:	120761379(PIGL)

SATI:

136370157(PIGL)

FPG:	101912638(PIGL)

FCH:	102055774(PIGL)

CCRI:

104165515(PIGL)

NNT:	104406373(PIGL)

SHAB:

115601992(PIGL)

ACUN:

113487384(PIGL)

TALA:

104365226(PIGL)

ACHC:

115346877(PIGL)

HALD:

104312589(PIGL)

HLE:	104835777(PIGL)

AGEN:

126039616

HHAR:

128148827(PIGL)

GCL:

127024485

CSTI:

104560195(PIGL)

LDI:	104350397(PIGL)

DPUB:

104302814(PIGL)

PPUS:

135187332(PIGL)

EGZ:	104121860(PIGL)

NNI:	104012203(PIGL)

PCRI:

104027667(PIGL)

PCAO:

104044709(PIGL)

PADL:

103920812(PIGL)

AFOR:

103897994(PIGL)

GSTE:

104260653(PIGL)

CLV:	102083477(PIGL)

MUI:	104547147(PIGL)

PGUU:

104471835(PIGL)

PLET:

104628814(PIGL)

EHS:	104504224(PIGL)

CMAC:

104474474(PIGL)

CUCA:

104057183(PIGL)

TEO:	104379551(PIGL)

BREG:

104643293(PIGL)

OHA:	104339637(PIGL)

ACAR:

104533027(PIGL)

CPEA:

104384824(PIGL)

CVF:	104284415(PIGL)

RTD:	128912798(PIGL)

AAM:	106493758(PIGL)

AROW:

112960666(PIGL)

NPD:	112945382(PIGL)

TGT:	104572424(PIGL)

DNE:	112983955(PIGL)

SCAM:

104142843(PIGL)

ASN:	102367899(PIGL)

AMJ:	102564394(PIGL)

CPOO:

109317213(PIGL)

GGN:	109293344(PIGL)

PSS:	102460170(PIGL)

CMY:	102936569(PIGL)

DCC:	119844867(PIGL)

CPIC:

101946503(PIGL)

TST:	117867299(PIGL)

CABI:

116827111(PIGL)

MRV:	120387458(PIGL)

ASAO:

132763406(PIGL)

PVT:	110087404(PIGL)

SUND:

121916938(PIGL)

PBI:	103058331(PIGL)

PMUR:

107299333(PIGL)

CTIG:

120298044(PIGL)

TSR:	106554922(PIGL)

PGUT:

117658918(PIGL)

APRI:

131188623(PIGL)

PTEX:

113451927(PIGL)

NSS:	113426809(PIGL)

VKO:	123023580(PIGL)

PMUA:

114585391(PIGL)

PRAF:

128403045(PIGL)

ZVI:	118097226(PIGL)

HCG:	128335993(PIGL)

GJA:	107119552(PIGL)

STOW:

125445570(PIGL)

EMC:	129344546(PIGL)

XLA:	108707935(pigl.L)

XTR:	100495759(pigl)

NPR:	108800136(PIGL)

RTEM:

120927738(PIGL)

BBUF:

120994645(PIGL)

BGAR:

122930390(PIGL)

MUO:	115482450(PIGL)

GSH:	117349081(PIGL)

DRE:	561471(pigl)

SRX:	107718344 107746821

SANH:

107676669 107680910

SGH:	107552588 107575753

CCAR:

109070912 109090018 109090412

CAUA:

113049165 113078399

CGIB:

128001624

PTET:

122345951(pigl)

LROH:

127165360(pigl)

OMC:	131540227(pigl)

PPRM:

120461774(pigl)

RKG:	130103753(pigl)

MAMB:

125267040(pigl)

CIDE:

127513643

CERY:

137034750(pigl)

MASI:

127440160

TROS:

130568533(pigl)

TDW:	130419454(pigl)

MANU:

129440586(pigl)

IPU:

108259871

IFU:	128603472(pigl)

PHYP:

113531584(pigl)

SMEO:

124379085(pigl)

TFD:	113634173(pigl)

TVC:	132840836(pigl)

TRN:	134303308(pigl)

AMEX:

103035262(pigl)

CMAO:

118814786(pigl)

EEE:	113589992(pigl)

CHAR:

105907613(pigl)

TRU:	101063673(pigl)

TFS:	130537127(pigl)

LCO:	104923434(pigl)

NCC:	104963937(pigl)

TBEN:

117470073(pigl)

CGOB:

115018737(pigl)

PGEO:

117459005(pigl)

GACU:

117557265(pigl)

EMAC:

134872553(pigl)

ELY:	117263815(pigl)

EFO:	125898871(pigl)

SLUC:

116058134(pigl)

ECRA:

117955534(pigl)

ESP:	116700546(pigl)

PFLV:

114567295(pigl)

GAT:	120821514(pigl)

PPUG:

119215045(pigl)

AFB:	129113982(pigl)

CLUM:

117743214(pigl)

PSWI:

130189922(pigl)

CANA:

137802801(pigl)

CVE:	137886805(pigl)

MSAM:

119895302(pigl)

SCHU:

122888112(pigl)

CUD:	121518689(pigl)

ALAT:

119031696(pigl)

ASTR:

137605928(pigl)

MZE:	101469666(pigl)

ONL:	100708562(pigl)

OAU:	116331916(pigl)

OLA:	101171602(pigl)

OML:	112142423(pigl)

CSAI:

133459799(pigl)

XMA:	102218960(pigl)

XCO:	114152815(pigl)

XHE:	116728180(pigl)

PRET:

103476038(pigl)

PFOR:

103133865(pigl)

PLAI:

106936215(pigl)

PMEI:

106933199(pigl)

GAF:	122845201(pigl)

PPRL:

129368499(pigl)

CVG:	107091739(pigl)

CTUL:

119791471(pigl)

GMU:	124876503(pigl)

NFU:	107386643(pigl)

KMR:	108233850(pigl)

ALIM:

106525396(pigl)

NWH:	119420617(pigl)

AOCE:

111575189(pigl)

EJA:	138196673(pigl)

BFRE:

138622144(pigl)

MCEP:

125020824(pigL)

CSEM:

103394906(pigl)

POV:	109628547(pigl)

SSEN:

122779632(pigl)

HHIP:

117774057(pigl)

HSP:	118122371(pigl)

PPLT:

128457513(pigl)

SMAU:

118301176(pigl)

LCF:

108893224

SDU:	111222279(pigl)

SLAL:

111663977(pigl)

XGL:	120802788(pigl)

HCQ:	109531124(pigl)

SSCV:

125982719(pigl)

SBIA:

133491544(pigl)

PEE:	133415641(pigl)

PTAO:

133467571(pigl)

BPEC:

110165145(pigl)

MALB:

109960400(pigl)

BSPL:

114870071(pigl)

SJO:	128370855(pigl)

SASA:

100196068(pigl)

STRU:

115148851

OTW:	112257860(pigl)

OMY:	110538889(pigl)

OGO:	124000365(pigl)

ONE:	115105528(pigl)

OKI:	109892749(pigl)

OKE:	118391153(pigl)

SALP:

111979976(pigl)

SNH:	120030303(pigl)

CCLU:

121573545(pigl)

ELS:	105027553(pigl)

SFM:	108936196(pigl)

PKI:	111854761(pigl)

AANG:

118236453(pigl)

CCOG:

133133048(pigl)

LOC:	102692169(pigl)

PSPA:

121308434(pigl)

ARUT:

117429019 117430253 117962585 117963248

PSEX:

120531552(pigl)

LCM:	102348270(PIGL)

CMK:	103180539(pigl)

RTP:	109931669(pigl)

CPLA:

122561891(pigl)

HOC:	132830432(pigl)

LERI:

129710505(pigl)

PMRN:

116950241(PIGL)

LRJ:	133348793(PIGL)

BFO:

118425647

BBEL:

109482755

CIN:

104266429

SCLV:

120334111

SPU:

100893824

LPIC:

129254904

APLC:

110986240

ARUN:

117306339

AJC:

117109619

SKO:

100377567

DME:	Dmel_CG4433(PIG-L)

DER:

6553944

DSE:

6620393

DSI:	Dsimw501_GD20086(Dsim_GD20086)

DYA:	Dyak_GE25096

DAN:

6500126

DSR:

110187621

DPO:

4803073

DPE:

6594413

DMN:

108155534

DWI:

6649787

DGR:

6567994

DMO:	Dmoj_GI10317

DAZ:

108621035

DNV:

108659677

DHE:

111602076

DVI:

6632556

CCAT:

101456226

BOD:

106623776

BDR:

105228520

RZE:

108366301

AOQ:

129252688

TDA:

119681044

MDE:

101889913

SCAC:

106088672

LCQ:

111684101

LSQ:

119602698

GFS:

119639188

ECOE:

129940059

CLON:

129613023

HIS:

119660237

AGA:

1281168

ACOZ:

120949637

AARA:

120895283

AMER:

121589068

ASTE:

118506559

AFUN:

125761236

AMOU:

128309590

AALI:

118461315

AAG:

5564160

AALB:

109402830 109422648

ASUA:

134227159

CQU:	CpipJ_CPIJ011635 CpipJ_CPIJ015317

CPII:

120413958

CNS:

116349693

BCOO:

119075905

LLL:

129795819

PPAP:

129809685

AME:

724648

ACER:

108002720

ALAB:

122718145

ADR:

102674891

AFLR:

100873055

BIM:

100744041

BBIF:

117206532

BVK:

117236779

BVAN:

117157631

BHUN:

126868300

BTER:

100651477

BAFF:

126918804

BPYO:

122572832

BPAS:

132907979

FVI:

122537091

CCAL:

108623105

OBB:

114876382

OLG:

117611994

NMEA:

116427899

CGIG:

122398006

SOC:

105195159

MPHA:

105835865

AEC:

105148343

ACEP:

105626316

PBAR:

105432330

VEM:

105568865

HST:

105188524

DQU:

106740738

CFO:

105250348

FEX:

115233660

LHU:	105679654(PIG-L)

PGC:

109852494

OBO:

105284269

PCF:

106791105

PFUC:

122523877

VPS:

122637261

VCRB:

124432497

VVE:

124957348

NVI:

100122783

CSOL:

105363537

TPRE:

106657918

LHT:

122508931

LBD:

127283865

MDL:

103572054

CGLO:

123261936

FAS:

105269828

DAM:

107041701

AGIF:

122848739

CINS:

118069151

VCAN:

122419366

CCIN:

107266937

DSM:

124407775

NPT:	124213965(PIG-L)

NFB:

124177524

NLO:

107218983

NVG:

124300081

AROA:

105692263

TCA:

660665

DPA:

109543753

SOY:

115888716

AGRG:

126748562

ATD:

109606677

CSET:

123320734

AGB:

108916869

LDC:

111502722

NVL:

108566534

APLN:

108734528

PPYR:

116161596

OTU:

111415325

BMOR:

101746769

BMAN:

114246777

MSEX:

115455622

DPL:	KGM_206970

BANY:

112048429

MJU:

123871218

NIQ:

126775580

VCD:

124533167

MCIX:

123663490

PMAC:

106714524

PPOT:

106108619

PXU:

106117681

BPHI:

137923955(PIG-L)

PRAP:

110993300

PBX:

123712840

PNAP:

125056756

ZCE:

119834621

CCRC:

123700036

LSIN:

126974033

AAGE:

121728272

HAW:

110373638

HZE:

124639717

TNL:

113494428

SLIU:

111360300

OFU:

114350921

ATRA:

106129937

GMW:

113515074

PXY:

105388117

PGW:

126376045

LGLY:

125236473

CSTB:

134750008

CFEL:

113369530

CCRN:

123301796

API:

100167541

DNX:

107172365

AGS:

114128690

RMD:

113559355

ACOO:

126833301

DVT:

126906760

BTAB:

109044356

DCI:

103522019

CLEC:

112126101

NLU:

111043804

HVI:	124367314 124368775

MQU:	128983132 128983134 128996559

PHU:	Phum_PHUM608680

FOC:

113211457

ZNE:

110826862

CSEC:

111867586

SGRE:

126284050

BROR:

134537645

IEL:

124156507

FCD:

110862038

DPX:	DAPPUDRAFT_306215

DMK:

116915433

DPZ:

124314222

AFRA:

136036126 136037722

PVM:

113800242

PJA:

122251977

PCHN:

125039483

PMOO:

119586471

HAME:

121875357

PCLA:

123757290(PIG-L)

CQD:	128692723(PIG-L)

PTRU:

123503456

ESN:

126988518

MNZ:

135199542

MRJ:	136829782(PIG-L)

HAZT:

108681001

EAF:

111699949

LSM:

121126444

TCF:

131882148

PPOI:

119110239

DSV:

119445898

RSAN:

119390271 119390322

RMP:

119172448

VDE:	111249058 111253122

VJA:	111267876 111273462

TUT:

107370939

DPTE:

113795728 113799052

DFR:

124499379

CSCU:

111635127

CVS:	136989889(PIG-L)

PTEP:

107439256

ABRU:

129972296

UDV:	129221251 129233220

SDM:

118182218

LPOL:

106463675

PMEO:

129583656

CEL:	CELE_Y52B11C.1(pigl-1)

CBR:

CBG_07954

CRQ:	GCK72_003496

NAI:	NECAME_08562

BMY:	BM_BM6741(Bm6741)

LOA:	LOAG_01808

HRO:	HELRODRAFT_116956

LGI:	LOTGIDRAFT_85239

PVUL:

126823461

PCAN:

112563366

BGT:	106068049 106074485

GAE:

121389389

HRF:

124132046

HRJ:

124266082

HASI:

137285436

CRG:

117692916

CANU:

128187479

CVN:

111132406

OED:

125663504

MYI:

110455343

PMAX:

117332441

AIRR:

138332001

MCAF:

127736762

MMER:

123544956

RPHI:

132745347

DPOL:

127875233

MAEA:

128209088

OBI:

106871685

OSN:

115224372

LJP:

135476433

LAK:

106178096

SMM:	Smp_035080

SHX:	MS3_00005829

EGL:

EGR_06091

LLON:

135483461

NVE:

5522386

EPA:

110254092

ATEN:

116288830

ADF:

107340845

AMIL:

114968583

MCAZ:

138047410

MFOO:

137976411

PDAM:

113665209

SPIS:

111326147

DGT:

114523576

XEN:

124434140

HMG:	100200643 105843857 105847287

HSY:	130622933 130662308

RES:

135684956

TAD:	TRIADDRAFT_57271

AQU:

105312184

ATH:	AT2G27340 AT3G58130

ALY:

9314258

CRB:	17874174 17875222 17885041

CSAT:

104712503 104781731 104792110

EUS:	EUTSA_v10002036mg EUTSA_v10002077mg

BRP:	103830144 103841710

BNA:	106353203 106406456 111197751

BOE:	106300305 106312636

RSZ:	108817070 108856689

THJ:

104822320

CPAP:

110823278 110825370

CIT:

102615400

CIC:	CICLE_v10002226mg

PVY:

116112678

MINC:

123229547

TCC:

18611788

GRA:

105780528

GHI:	107959467 107959595

GAB:

108457889

HSYR:

120184626 120195513 120199974

DZI:

111293471

EGR:

104433400

RARG:

115737246 115748737

GMX:	100527883 100802133

GSJ:	114412636 114421453

PVU:

137811757

VRA:

106752828

VAR:

108319347

VUN:

114178631

VUM:

124840388

CCAJ:

109813222

APRC:

113857442

MTR:

25493372

TPRA:

123916828

CAM:

101500559

PSAT:

127117894

VVO:

131598680

LJA:	130714473 130723546

ADU:

107481686

AIP:

107631546

AHF:	112734570 112792359

LANG:

109350924

PCIN:

129290701 129292155

QSA:	O6P43_008445 O6P43_031115

FVE:	101291478 101300630 101303516

AANS:

126793288

RCN:

112180313

PPER:

18777426

PMUM:

103337156

PAVI:

110757117

PDUL:

117627928

MDM:

103440777

MSYL:

126607476

PXB:	103937420 103937427

ZJU:

107419488

MNT:

21388662

CSAV:

115722477

CSV:

101217265

CMO:

103494031

BHJ:

120071635

MCHA:

111007488

CMAX:

111485360

CMOS:

111429838

CPEP:

111779943

RCU:

8266989

MEAN:

126660192

JCU:

105637339

HBR:

110658374

MESC:

110621439

POP:

7485181

PEU:

105108204

PALZ:

118044317

PNZ:

133678308

JRE:	108993226 109012096

CILL:

122296108

CAVE:

132184544

AGLU:

133865389

QSU:

112007384

QLO:

115959692

TWL:	119981286 119986546 119986548

VVI:

100855158

VRI:

117918891

SLY:	101246849 101265988

SPEN:

107003224 107027216 114078449

SOT:	102587610 102587734

SSTN:

125842224 125844851

SDUL:

129889492 129903007

CANN:

107854389 107860255

LBB:	132627128 132635572

NTA:	107785969 107812760

NSY:

104210665

NTO:

104109323

NAU:

109241736

INI:	109188637 109191435

ITR:

116032785

SIND:

105158225

OEU:

111412222

EGT:

105975896

SSPL:

121792337 121799728 121808087

SMIL:

130989857 130991023 130998984

SHIS:

125209990 125218714

APAN:

127242019 127253090

HAN:

110911683

ECAD:

122585016 122592197

LSV:

111890830

CCAV:

112526341

DCR:

108192926

CSIN:

114272831 114290511 114303980

RVL:	131329750 131336033

AEW:	130750361 130760680

DLT:

127790021

BVG:

104902233

SOE:

110801269

CQI:	110691002 110707761 110732695

ATRI:

130814975

MOF:

131148705

NNU:

104610190

MING:

122080774

TSS:

122663640

PSOM:

113332652 113346804

OSA:

4337416

DOSA:

Os04g0678800

OBR:

102720790

OGL:

127770996

BDI:

100825685

ATS:

109751895

TDC:	119357128 119357183 119366409 119366474

TAES:

123047419 123047484 123055223 123191058 123191103

TUA:	125540301 125540410

LPER:

127331154 127337120

LRD:	124674748 124675230 124675376

SBI:	8073588 8076469

ZMA:	100283695 100381427

MFLO:

136493246 136494122 136494217 136497996 136498109

SITA:

101763343

SVS:

117849442

PVIR:

120642128 120682709

PHAI:

112899762

PAUA:

133887738 133925241

PDA:

103698060

EGU:

105058989

MUS:

104000505

ZOF:	122043096 122047600

DCT:

110115193

PEQ:

110018890

AOF:

109848368

MSIN:

131237042

ACAK:

137958405

NCOL:

116259782

ATR:

18424082

CJF:

131048312

PPP:

112290847

CRE:	CHLRE_06g300100v5

VCN:	VOLCADRAFT_104217

MNG:

MNEG_9538

CSL:	COCSUDRAFT_43370

CVR:	CHLNCDRAFT_33970

OLU:	OSTLU_34729

OTA:	OT_ostta09g00420

BPG:	Bathy10g03980

MIS:	MICPUN_76326

SCE:	YMR281W(GPI12)

SEUB:

DI49_4367

SPAO:

SPAR_M03960

AGO:	AGOS_ABL120W

ERC:

Ecym_4617

KLA:	KLLA0_D01430g

KMX:	KLMA_80045(GPI12)

LTH:	KLTH0C03740g

VPO:	Kpol_1068p4

ZRO:	ZYRO0G14300g

CGR:	2891487(GVI51_M02915)

NCS:	NCAS_0C00380(NCAS0C00380)

NDI:	NDAI_0K00330(NDAI0K00330)

TPF:	TPHA_0I00280(TPHA0I00280)

TBL:	TBLA_0B03300(TBLA0B03300)

TGB:	HG536_0H00540

TDL:	TDEL_0B00520(TDEL0B00520)

KAF:	KAFR_0B03960(KAFR0B03960)

KNG:	KNAG_0J00240(KNAG0J00240)

ZMK:	HG535_0C05650

DHA:	DEHA2F04246g

PIC:	PICST_30247(GPI12)

PGU:	PGUG_01294

SPAA:

SPAPADRAFT_141689

LEL:	PVL30_000645(GPI12)

LBG:	92205636(LODBEIA_P04400)

CAL:	CAALFM_C110320WA(CaO19.4903)

CTP:	CTRG_03326

COT:	CORT_0A06720

CDU:	CD36_09720

CTEN:

18246396(GPI12)

CLU:	CLUG_01303

CLUS:

A9F13_06g01067

CAUR:

CJI96_0000732

PPA:	PAS_chr1-1_0044

PKZ:	C5L36_0E03510

BNN:	FOA43_000031

BBRX:

BRETT_001085

OPA:	HPODL_04971

YLI:	2911962(YALI2_E00444g)

SLB:	AWJ20_2149(GPI12)

NCR:

NCU09510

NTE:	NEUTE1DRAFT80698(NEUTE1DRAFT_80698)

SMP:	10802558(SMAC4_07868)

PAN:	PODANSg2422 PODANSg4679

PBEL:

QC761_701520(GPI12) QC761_703690

PPSD:

QC762_701520(GPI12) QC762_703690

PPSP:

QC763_701520(GPI12) QC763_703690

PPSA:

QC764_701520(GPI12) QC764_703690

TTT:	THITE_2118345 THITE_2120324

MTM:	MYCTH_2315009

MGR:

MGG_05020

PPEI:

PpBr36_03395

PGRI:

PgNI_01284

TMN:	UCRPA7_5372

SSCK:

SPSK_06489 SPSK_07496

FGR:	FGSG_12307

FPU:	FPSE_00115

FPOA:

FPOAC1_006544

FVN:	FVRRES_07149

FVR:	FVEG_10283

FOX:	FOXG_11539

FFC:	NCS54_00829700

FKR:	NCS57_00872900

FMU:	J7337_011555

TRE:	TRIREDRAFT_3101 TRIREDRAFT_58550

TRR:	M419DRAFT_24178 M419DRAFT_74933

TATV:

25779591(TrAtP1_005486)

TASP:

36612568(TrAFT101_011739)

MAW:	19245944(GPI12_1) 19250576(J3458_017732)

MAJ:	MAA_02464 MAA_09568

MBRN:

26240068(GPI12) 26245799(pigL)

PCHM:

VFPPC_00025 VFPPC_08272

CMT:

CCM_08051

AMUS:

LMH87_010723

PLJ:	28884537(PLICBS_005780) 28891865(PLICBS_003973)

PTKZ:

JDV02_001979 JDV02_003583(GPI12_2)

VDA:	VDAG_09637

CFJ:	CFIO01_07186

CLUP:

CLUP02_02550

CHIG:

CH63R_01937

CDET:

87936659(CDEST_00156)

SAPO:

SAPIO_CDS0304 SAPIO_CDS2073

ELA:	UCREL1_6684

PFY:	PFICI_05895

SSL:	SS1G_11606

BFU:	BCIN_08g06410

MBE:

MBM_03823

PSCO:

LY89DRAFT_269971 LY89DRAFT_600243

GLZ:	GLAREA_03813

ANI:	ANIA_00049

AFM:	AFUA_5G12550

ACT:	ACLA_015600

NFI:	NFIA_074660

AOR:	AO090005001316 AO090120000381

ANG:	An05g02300 An14g06640

AFV:	AFLA_004139 AFLA_009598

ALUC:

AKAW2_41275A(GPI12) AKAW2_81373S

ACHE:

ACHE_41283S(GPI12)

APUU:

APUU_12107A(GPI12)

PCS:	N7525_006915

PDP:	PDIP_82260

POU:	POX_d05373

TMF:	EYB26_000254 EYB26_005855 EYB26_008687

TRG:	TRUGW13939_04198 TRUGW13939_06390

CIM:	CIMG_09320

CPW:	9692721(GPI12)

URE:	UREG_04986

ABE:

ARB_03399

TVE:

TRV_08084

PBL:	PAAG_02520

PBN:	PADG_05666

AJE:	HCAG_02566

BGH:	BDBG_08241

PNO:	SNOG_09981

PTE:

PTT_15068

PTRR:

6343823(PtrM4_108880)

BZE:	COCCADRAFT_99487

BSC:	COCSADRAFT_88447

BOR:	COCMIDRAFT_90591

AALT:

CC77DRAFT_930647

ADAC:

96084612(ACET3X_004290)

ARAB:

EKO05_0005489

ZTR:	MYCGRDRAFT_84825

PFJ:	MYCFIDRAFT_82599

FFU:	CLAFUR5_03724 CLAFUR5_05568

CBET:

CB0940_03251

BCOM:

BAUCODRAFT_415244

NPA:	UCRNP2_8734

TML:	GSTUM_00007684001

SPO:	2543490(gpi12)

SOM:	SOMG_05098(gpi12)

CNE:

CNC00580

CNB:

CNBC6650

CNG:	CNAG_03026

CGI:	CGB_C9160W

CDEU:

CNBG_3667

CDEP:

91084889(L203_100675)

KMG:	30167034(I203_101654)

KNE:	92178027(IAR55_000767)

TMS:	TREMEDRAFT_18134

TASA:

A1Q1_02348

CCAC:

CcaHIS019_0206700(GPI12)

PPL:	POSPLDRAFT_95275

TVS:	TRAVEDRAFT_130414

DSQ:	DICSQDRAFT_111859

PCO:	PHACADRAFT_45927

SHS:	STEHIDRAFT_138191

HIR:	HETIRDRAFT_126598

PSQ:	PUNSTDRAFT_102951

ADL:	AURDEDRAFT_71436

FME:	FOMMEDRAFT_130360

GTR:	GLOTRDRAFT_108705

LBC:	LACBIDRAFT_297620

CCI:	CC1G_11076

ABP:	AGABI1DRAFT118528(AGABI1DRAFT_118528)

ABV:	AGABI2DRAFT183645(AGABI2DRAFT_183645)

MRR:	Moror_4489

E1B28_005773

SCM:	SCHCO_01159603(SCHCODRAFT_01159603)

CPUT:

CONPUDRAFT_128040

SLA:	SERLADRAFT_458076

WSE:	WALSEDRAFT_31689

WIC:	J056_000065

UMA:	UMAG_00302

PFP:	PFL1_00298

SGRA:

EX895_000531

MGL:

MGL_0955

MRT:

MRET_3195

MSYM:

MSY001_2666(GPI12)

PGR:	PGTG_12159 PGTG_19418

PTRC:

PtA15_16A313

PSTR:

Pst134EA_029248

MLR:	MELLADRAFT_116860 MELLADRAFT_118612

ECU:	ECU08_0300

EIN:	Eint_080220

EHE:	EHEL_080220

ERO:	EROM_080220

NCE:	NCER_100856

VNX:	VNE69_03303

RIE:	OCT59_020521

DDI:	DDB_G0293136(pigL)

DPP:	DICPUDRAFT_92416

DFA:	DFA_12225(pigL)

EHI:	EHI_015270(52.t00009)

EDI:	EDI_239010

EIV:	EIN_429650

ACAN:

ACA1_383150

PFA:	PF3D7_0624700

PFD:	PFDG_04448

PFH:	PFHG_00599

PREI:

PRSY57_0623100

PGAB:

PGSY75_0624700

PLAG:

39740862(PADL01_0622800)

PYO:	PY17X_1125000

PCB:	PCHAS_1123100

PBE:	PBANKA_1123600

PVV:	PVVCY_1102470

PKN:	PKNH_1125500

PMAL:

PMUG01_11038900

PBRS:

92371813(MKS88_003726)

PREL:

PRELSG_1123600

PCOT:

PCOAH_00034370

TAN:

TA10880

TPV:

TP04_0615

BEQ:	BEWA_007030

BBO:	BBOV_III007080

BMIC:

BmR1_04g06360

BBIG:

BBBOND_0306960 BBBOND_0306990 BBBOND_0307000 BBBOND_0307020 BBBOND_0307030

CPV:

cgd7_700

TGO:	TGME49_258110

BBES:

BESB_084140

TET:	TTHERM_00471420

PTM:	GSPATT00009494001 GSPATT00019956001

PTI:	PHATRDRAFT_34610

FCY:	FRACYDRAFT_228990

TPS:	THAPSDRAFT_8003

NGD:	NGA_2035300(PIGL)

AAF:	AURANDRAFT_55121

PIF:	PITG_14810

PSOJ:

PHYSODRAFT_325650 PHYSODRAFT_510442

SPAR:

SPRG_10910

TBR:	Tb11.01.3900

TBG:	TbgDal_XI13520

TCR:	504005.20 511481.40

LMA:	LMJF_09_0040(GPI12)

LIF:	LINJ_09_0060(GPI12)

LDO:	LDBPK_090060

LMI:	LMXM_09_0040

LMAT:

92517404(LSCM1_07525)

LBZ:	LBRM_09_0060

LPAN:

LPMP_090060(GPI12)

LOI:	92362543(LSCM4_06695)

LEIS:

94182451(GH5_07189)

LENR:

94174293(CUR178_07134)

LEIN:

94190399(JIQ42_06798)

PHET:

94292829(JKF63_06804)

NGR:	NAEGRDRAFT_33046

GTT:	GUITHDRAFT_54525

» show all

Reference

1 [PMID:2525555]

Authors

Doering TL, Masterson WJ, Englund PT, Hart GW.

Title

Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Origin of the non-acetylated glucosamine.

Journal

J Biol Chem 264:11168-73 (1989)

Reference

2 [PMID:9188481]

Authors

Nakamura N, Inoue N, Watanabe R, Takahashi M, Takeda J, Stevens VL, Kinoshita T.

Title

Expression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylase.

Journal

J Biol Chem 272:15834-40 (1997)
DOI:10.1074/jbc.272.25.15834

Sequence

[rno:192263]

Reference

3 [PMID:10085243]

Authors

Watanabe R, Ohishi K, Maeda Y, Nakamura N, Kinoshita T.

Title

Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis.

Journal

Biochem J 339 ( Pt 1):185-92 (1999)

Sequence

[sce:YMR281W] [rno:192263] [hsa:9487]

Reference

4 [PMID:11432820]

Authors

Smith TK, Crossman A, Borissow CN, Paterson MJ, Dix A, Brimacombe JS, Ferguson MA.

Title

Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

Journal

EMBO J 20:3322-32 (2001)
DOI:10.1093/emboj/20.13.3322