KEGG ENZYME: 2.4.1.189

ENZYME: 2.4.1.189

Entry

EC 2.4.1.189                Enzyme

Name

luteolin 7-O-glucuronosyltransferase;
uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase;
LGT;
UDP-glucuronate:luteolin 7-O-glucuronosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

UDP-alpha-D-glucuronate:luteolin 7-O-glucuronosyltransferase (configuration-inverting)

Reaction(IUBMB)

UDP-alpha-D-glucuronate + luteolin = UDP + luteolin 7-O-beta-D-glucuronide [RN:R03589]

Reaction(KEGG)

R03589

Substrate

UDP-alpha-D-glucuronate [CPD:C00167];
luteolin [CPD:C01514]

Product

UDP [CPD:C00015];
luteolin 7-O-beta-D-glucuronide [CPD:C03515]

Comment

The enzyme participates in the biosynthesis of luteolin triglucuronide, the major flavone found in the photosynthetically-active mesophyll of the primary leaves of Secale cereale (rye).

History

EC 2.4.1.189 created 1992

Pathway

ec00944

Flavone and flavonol biosynthesis

Reference

Authors

Schulz M, Weissenbock G.

Title

3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale.

Journal

Phytochemistry 27:1261-1267 (1988)