ID UREF_GLOC7 Reviewed; 232 AA.
AC B7K911;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 29-MAY-2024, entry version 60.
DE RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385};
GN OrderedLocusNames=PCC7424_4416;
OS Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC
OS 7424)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Gloeothece; Gloeothece citriformis.
OX NCBI_TaxID=65393;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7424;
RX PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA Sherman L.A., Pakrasi H.B.;
RT "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT unicellular nitrogen-fixing Cyanobacteria.";
RL MBio 2:E214-E214(2011).
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
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DR EMBL; CP001291; ACK72780.1; -; Genomic_DNA.
DR RefSeq; WP_015956364.1; NC_011729.1.
DR AlphaFoldDB; B7K911; -.
DR SMR; B7K911; -.
DR STRING; 65393.PCC7424_4416; -.
DR KEGG; cyc:PCC7424_4416; -.
DR eggNOG; COG0830; Bacteria.
DR HOGENOM; CLU_049215_4_0_3; -.
DR OrthoDB; 9798772at2; -.
DR Proteomes; UP000002384; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.4190.10; Urease accessory protein UreF; 1.
DR HAMAP; MF_01385; UreF; 1.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR PANTHER; PTHR33620; UREASE ACCESSORY PROTEIN F; 1.
DR PANTHER; PTHR33620:SF1; UREASE ACCESSORY PROTEIN F; 1.
DR Pfam; PF01730; UreF; 1.
DR PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT CHAIN 1..232
FT /note="Urease accessory protein UreF"
FT /id="PRO_1000145113"
SQ SEQUENCE 232 AA; 25795 MW; C00CC2F0DF775A2D CRC64;
MNHSLLAPKL ALMQLSDSFF PSGSFTLSHG LEALAQGEQI HSIKDLEIFL QILLHNKLGT
TDLVALIHAY RGSKREDLDA VREADHQLFA QTLIEKNREM GRKSGRALLM VARETWQDTQ
LETLEKETAK GTINGLHPII FAVVGRVAGL SETDTGLAFL HSFITGLLGA AIRLNIIGHL
QAQKILLKLA PDLETTYQKA TEINLNEMFS CTPLIDIAQM NHQNLDYRLF AN
//
