ID UREF_DELAS Reviewed; 238 AA.
AC A9BUC2;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 29-MAY-2024, entry version 62.
DE RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=Daci_1180;
OS Delftia acidovorans (strain DSM 14801 / SPH-1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Delftia.
OX NCBI_TaxID=398578;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14801 / SPH-1;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Schleheck D., Richardson P.;
RT "Complete sequence of Delftia acidovorans DSM 14801 / SPH-1.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
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DR EMBL; CP000884; ABX33825.1; -; Genomic_DNA.
DR RefSeq; WP_012203111.1; NC_010002.1.
DR AlphaFoldDB; A9BUC2; -.
DR SMR; A9BUC2; -.
DR STRING; 398578.Daci_1180; -.
DR GeneID; 24116936; -.
DR KEGG; dac:Daci_1180; -.
DR eggNOG; COG0830; Bacteria.
DR HOGENOM; CLU_049215_2_1_4; -.
DR Proteomes; UP000000784; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.4190.10; Urease accessory protein UreF; 1.
DR HAMAP; MF_01385; UreF; 1.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR PANTHER; PTHR33620; UREASE ACCESSORY PROTEIN F; 1.
DR PANTHER; PTHR33620:SF1; UREASE ACCESSORY PROTEIN F; 1.
DR Pfam; PF01730; UreF; 1.
DR PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT CHAIN 1..238
FT /note="Urease accessory protein UreF"
FT /id="PRO_0000344119"
SQ SEQUENCE 238 AA; 25766 MW; 216C3CFFFB6AF37A CRC64;
MADLSIQGLC ALLHLASPQL PVGGFSYSQG LEAAIEHGLV TDAGTARTWI ADALAHGFAR
CEAPLWLLLR RAWSAGDEGA VHEWNQWFIA SRDSREARAE TLQMGWSLHS LLRSVPWGGE
AFAPRIAQLG ALVEGAGLAY PTAFACACAA VDADEDHALL AYGFAWLENQ VAAAIKAVPL
GQVAGQSLLL ALHPLLEQAV CEARRRASEA PPRLDTMLPQ WSVLQARHEH QYSRLFRS
//
