ID   ACPX_STRVG              Reviewed;          88 AA.
AC   P41174;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   02-OCT-2024, entry version 86.
DE   RecName: Full=Monensin polyketide synthase acyl carrier protein;
DE            Short=ACP;
OS   Streptomyces virginiae (Streptomyces cinnamonensis).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A3823.5;
RX   PubMed=1508151; DOI=10.1007/bf00283846;
RA   Arrowsmith T.J., Malpartida F., Sherman D.H., Birch A., Hopwood D.A.,
RA   Robinson J.A.;
RT   "Characterisation of actI-homologous DNA encoding polyketide synthase genes
RT   from the monensin producer Streptomyces cinnamonensis.";
RL   Mol. Gen. Genet. 234:254-264(1992).
CC   -!- FUNCTION: Acyl carrier protein.
CC   -!- PATHWAY: Antifungal biosynthesis; monensin biosynthesis.
CC   -!- PTM: 4'-phosphopantetheine is transferred from CoA to a specific serine
CC       of the apo-ACP-like protein. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z11511; CAA77598.1; -; Genomic_DNA.
DR   PIR; S25078; S25078.
DR   AlphaFoldDB; P41174; -.
DR   SMR; P41174; -.
DR   UniPathway; UPA00178; -.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis; Phosphopantetheine; Phosphoprotein.
FT   CHAIN           1..88
FT                   /note="Monensin polyketide synthase acyl carrier protein"
FT                   /id="PRO_0000180250"
FT   DOMAIN          5..82
FT                   /note="Carrier"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
FT   MOD_RES         42
FT                   /note="O-(pantetheine 4'-phosphoryl)serine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
SQ   SEQUENCE   88 AA;  9429 MW;  A62AA9FC529C71E8 CRC64;
     MSDRPFTLAD LQRILVEAAG ADESAGPDDI LDTTFALLGY ESLALLETGG CIEREIGISL
     DDDTLTDALT PRELIDHVNE RLAAARVA
//