ID ACPH_SHIDS Reviewed; 143 AA.
AC Q32JF8;
DT 07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 27-NOV-2024, entry version 75.
DE RecName: Full=Putative acyl carrier protein phosphodiesterase;
DE Short=ACP phosphodiesterase;
DE EC=3.1.4.14;
GN Name=acpH; OrderedLocusNames=SDY_0330;
OS Shigella dysenteriae serotype 1 (strain Sd197).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300267;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sd197;
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- FUNCTION: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the
CC phosphopantetheine prosthetic group from ACP. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=holo-[ACP] + H2O = apo-[ACP] + (R)-4'-phosphopantetheine +
CC H(+); Xref=Rhea:RHEA:20537, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:9690,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999,
CC ChEBI:CHEBI:61723, ChEBI:CHEBI:64479; EC=3.1.4.14;
CC -!- SIMILARITY: Belongs to the AcpH family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. The N-terminus is
CC shorter than in related proteins. {ECO:0000305}.
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DR EMBL; CP000034; ABB60549.1; -; Genomic_DNA.
DR AlphaFoldDB; Q32JF8; -.
DR SMR; Q32JF8; -.
DR STRING; 300267.SDY_0330; -.
DR EnsemblBacteria; ABB60549; ABB60549; SDY_0330.
DR KEGG; sdy:SDY_0330; -.
DR HOGENOM; CLU_099370_1_0_6; -.
DR Proteomes; UP000002716; Chromosome.
DR GO; GO:0008770; F:[acyl-carrier-protein] phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR007431; ACP_PD.
DR PANTHER; PTHR38764; ACYL CARRIER PROTEIN PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR38764:SF1; ACYL CARRIER PROTEIN PHOSPHODIESTERASE; 1.
DR Pfam; PF04336; ACP_PD; 1.
PE 5: Uncertain;
KW Fatty acid biosynthesis; Fatty acid metabolism; Hydrolase;
KW Lipid biosynthesis; Lipid metabolism; Reference proteome.
FT CHAIN 1..143
FT /note="Putative acyl carrier protein phosphodiesterase"
FT /id="PRO_0000226275"
SQ SEQUENCE 143 AA; 17464 MW; 10319F9D40D95290 CRC64;
MTDNLPEVRE AREWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM
TILPDSLPRF INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLNAHY
AALETRFWQF YPRMMAQVSR KAL
//
