#=GF ID   E2R135
#=GF AC   PF11570.13
#=GF DE   Coiled-coil receptor-binding R-domain of colicin E2
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   pdb_2ysu
#=GF GA   21.40 21.40;
#=GF TC   21.40 21.90;
#=GF NC   21.30 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 81514348 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   17548346
#=GF RT   Structure of the complex of the colicin E2 R-domain and its BtuB
#=GF RT   receptor. The outer membrane colicin translocon. 
#=GF RA   Sharma O, Yamashita E, Zhalnina MV, Zakharov SD, Datsenko KA,
#=GF RA   Wanner BL, Cramer WA; 
#=GF RL   J Biol Chem. 2007;282:23163-23170.
#=GF DR   INTERPRO; IPR024566;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   E2 is a DNase which utilises the outer membrane receptor BtuB to
#=GF CC   bind to and enter the cell. This family of proteins is E2R135
#=GF CC   (residues 321-443) which is the part of E2 which is responsible
#=GF CC   for binding to BtuB in a coiled coil formation [1].
#=GF SQ   8
#=GS A0A8J3DT09_9HYPH/322-457  AC A0A8J3DT09.1
#=GS Q814D9_BACCR/26-122       AC Q814D9.1
#=GS A8ARS8_CITK8/226-361      AC A8ARS8.1
#=GS A0A941Z9Q9_9ENTR/1-30     AC A0A941Z9Q9.1
#=GS A0A3Q1G9J1_9TELE/27-127   AC A0A3Q1G9J1.1
#=GS A0A7X6K809_9MICC/322-457  AC A0A7X6K809.1
#=GS A7T1P2_NEMVE/1-63         AC A7T1P2.1
#=GS A0A1W2FEM3_9HYPH/25-90    AC A0A1W2FEM3.1
A0A8J3DT09_9HYPH/322-457             .................HPEEGLKRDYDKAKAELDAEDKNIATLNSRIAS..TEKALPGARAAVQEADKKVKEAEANKDDFVT...YNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLN...........
Q814D9_BACCR/26-122                  ........vgkkrlsrv--------------AKMIAPDLNVPSLGD-IASdvTEKVVDGAKESVKETAKDTREAQKKADDKVAdvlYKPPFKVSNKTKETLDRLHKNSTNS-----------------------------------------------kkvsaykdr..
A8ARS8_CITK8/226-361                 .................HPEEGLKREYDKAKAELDAEDKNIATLNSRIAS..TEKAIPGARAAVQEADKKVKEAEANKDDFVT...YNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLN...........
A0A941Z9Q9_9ENTR/1-30                ...............mk---------------------------------..-------------------------------...--------------------------------------------KSQAVLNAALESRKQKETKVKEAENKLN...........
A0A3Q1G9J1_9TELE/27-127              .....eqetdtflltst---------------------------------..-------------DEDSKHSEGEANSDQFLS...YNLPAN-ESPHQEGSKYVDSELS-RNAVVKPKKSHNREISHSNNVDKSSLSESHNDTDTGRK----------svkfdvcentf
A0A7X6K809_9MICC/322-457             .................HPEEGLKRDYDKAKAELDAEDKNIATLNSRIAS..TEKALPGARAAVQEADKKVKEAEANKDDFVT...YNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLN...........
A7T1P2_NEMVE/1-63                    ...............ee---------------------------------..-------------------------------...----------MQEKLRQLERDIQNSENKLKAAQDEKVELEEELGRARDGAEKSRDERKITESK---------kelkgrge...
A0A1W2FEM3_9HYPH/25-90               tllgaaasglalasapg---------------------------------..----VMAAPLAAKETDYKVTDKITSKEDATT...YNNFYEFGTGKDDPVRYS------------------------------------------------------gdfk.......
#=GC seq_cons                        ........................................................l.uA..uspEsDpKspEupsspDDhlo...YNsPachuoshQ-plRYL-+-lpNppthlKstpsp..thpcp.s+s+uuLstuh-sRKppEpK....................
//