KEGG   REACTION: R01274
Entry
R01274                      Reaction                               
Name
palmitoyl-CoA hydrolase
Definition
Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid
Equation
C00154 + C00001 <=> C00010 + C00249
Reaction class
RC00004  C00010_C00154
RC00014  C00154_C00249
Enzyme
3.1.2.2         3.1.2.22        3.1.2.-
Pathway
rn00062  Fatty acid elongation
rn01040  Biosynthesis of unsaturated fatty acids
rn01100  Metabolic pathways
rn01212  Fatty acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2
     R01274  Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid
    3.1.2.22
     R01274  Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid
    3.1.2.-
     R01274  Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid
Orthology
K01068  acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K01074  palmitoyl-protein thioesterase [EC:3.1.2.22]
K10804  acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]
K10805  acyl-CoA thioesterase II [EC:3.1.2.-]
K10806  acyl-CoA thioesterase YciA [EC:3.1.2.-]
K17360  acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
Reference
1  [PMID:4871199]
  Authors
Barnes EM Jr, Wakil SJ
  Title
Studies on the mechanism of fatty acid synthesis. XIX. Preparation and general properties of palmityl thioesterase.
  Journal
J Biol Chem 243:2955-62 (1968)
Reference
2  [PMID:4554913]
  Authors
Bonner WM, Bloch K.
  Title
Purification and properties of fatty acyl thioesterase I from Escherichia coli.
  Journal
J Biol Chem 247:3123-33 (1972)
Reference
3  [PMID:235694]
  Authors
Barnes EM Jr.
  Title
Long-chain fatty acyl thioesterases I and II from Escherichia coli.
  Journal
Methods Enzymol 35:102-9 (1975)
DOI:10.1016/0076-6879(75)35144-6
Reference
4  [PMID:4914740]
  Authors
Barnes EM Jr, Wakil SJ, Swindell AC.
  Title
Purification and properties of a palmityl thioesterase II from Escherichia coli.
  Journal
J Biol Chem 245:3122-8 (1970)
Other DBs
RHEA: 16648

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (16790)   
   KEGG ORTHOLOGY (6)   
   KEGG GENES (16784)   
All databases (16808)   

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