KEGG ORTHOLOGY: K12428

ORTHOLOGY: K12428

Entry

K12428                      KO

Symbol

fadD32

Name

fatty acyl-AMP ligase FadD32 [EC:6.2.1.-]

Pathway

map00074

Mycolic acid biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00887

Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM

Reaction

R13274

meromycolic-acid:holo-[acp Pks13] ligase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00074 Mycolic acid biosynthesis
    K12428  fadD32; fatty acyl-AMP ligase FadD32
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K12428  fadD32; fatty acyl-AMP ligase FadD32
Lipid biosynthesis proteins [BR:ko01004]
Acyl-AMP ligase
  Fatty acyl-AMP ligase (FAAL)
   K12428  fadD32; fatty acyl-AMP ligase FadD32

Other DBs

COG:

COG0318

Genes

MTU:	Rv3801c(fadD32)

MTV:	RVBD_3801c

MTC:

MT3908

MRA:	MRA_3841(fadD32)

MTF:	TBFG_13835

MTB:	TBMG_03848

MTK:	TBSG_03871

MTZ:	TBXG_003818

MTG:	MRGA327_23410

MTE:	CCDC5079_3530

MTUR:

CFBS_4030(fadD32)

MTL:	CCDC5180_3479

MTO:	MTCTRI2_3880(fadD32)

MTD:	UDA_3801c(fadD32)

MTN:	ERDMAN_4167(fadD32)

MTJ:	J112_20435

MTUB:

MT7199_3870

MTUE:

J114_20305

MTX:	M943_19525

MTUH:

I917_26725

MTUL:

TBHG_03739

MTUT:

HKBT1_4013(fadD32)

MTUU:

HKBT2_4023(fadD32)

MTQ:	HKBS1_4026(fadD32)

MBO:	BQ2027_MB3831C(fadD32)

MBB:	BCG_3863c(fadD32)

MBT:	JTY_3865(fadD32)

MBM:	BCGMEX_3864c(fadD32)

MBK:	K60_039430

MBX:

BCGT_3663

MAF:	MAF_38160(fadD32)

MMIC:

RN08_4195

MCE:	MCAN_38201(fadD32)

MCQ:	BN44_120208(fadD32)

MCV:	BN43_90316(fadD)

MCX:	BN42_90324(fadD)

MCZ:	BN45_110162(fadD)

MORY:

MO_003952(fadD32)

MLE:	ML0100(fadD32)

MLB:	MLBr00100(fadD32)

MPA:	MAP_0219(fadD32)

MAO:

MAVI:

MAVU:

MAV:

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MMAN_44690(fadD32)

MSER:

MTY59_21010(fadD32)

MSA:	Mycsm_06188

MUL:	MUL_4984(fadD32)

MMI:	MMAR_5365(fadD32)

MMAE:

MMARE11_51860(fadD32)

MLI:	MULP_05644(fadD32)

MPSE:

MPSD_54910(fadD32)

MSHO:

MSHO_08470(fadD32)

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_14175

MYV:	G155_28625

MYE:	AB431_28070

MHAD:

B586_03045

MDX:	BTO20_02275

MSHG:

MSG_04873(fadD32)

MFJ:	MFLOJ_36510(fadD32)

MSTO:

MSTO_40890(fadD32)

MSIM:

MSIM_25980(fadD32)

MSAK:

MSAS_32470(fadD32)

MKU:	I2456_27430

MLW:	MJO58_26845(fadD32)

MXE:	MYXE_02460(fadD32)

MNV:	MNVI_15390(fadD32)

MPAG:

C0J29_29620

MNM:	MNVM_20660(fadD32) MNVM_28120

MGOR:

H0P51_27445

MCOO:

MCOO_23070(fadD32_1) MCOO_30350(fadD32_2)

MBAI:

MB901379_04805

MSEO:

MSEO_38040(fadD32)

MHEK:

JMUB5695_00215(fadD32)

MGAU:

MGALJ_45350

MLJ:	MLAC_44270(fadD32)

MBRD:

MBRA_16990(fadD32)

MSHJ:

MSHI_34120(fadD32)

MMAM:

K3U93_24115(fadD32)

MSPG:

F6B93_21930

MOT:	LTS72_25815(fadD32)

MLM:	MLPF_0118(fadD32)

MPAA:

MKK62_00470(fadD32)

MMEH:

M5I08_00525(fadD32)

MKY:	IWGMT90018_61470(fadD32)

MADI:

A7U43_04800

MWU:	PT015_16880(fadD32) PT015_17300(fadD32)

MYJ:	BCA37_00760

MSM:	MSMEG_6393

MSG:	MSMEI_6225(fadD32)

MSB:	LJ00_31600

MSN:	LI99_31605

MSH:	LI98_31610

MVA:

Mvan_5641

MGI:

Mflv_1168

MSP:	Mspyr1_50190

MCB:	Mycch_4989

MNE:	D174_00420

MYN:	MyAD_00405

MFT:	XA26_57860

MPHL:

MPHLCCUG_00206

MVQ:

MYVA_5567

MLL:	B1R94_27275

MRH:	MycrhN_1944

MTHN:

4412656_04401

MHAS:

MHAS_04497

MDU:	MDUV_45860

MCHT:

MCHIJ_16560

MDR:	MDOR_35480

MAUU:

NCTC10437_05403

MMAG:

MMAD_51710

MMOR:

MMOR_07830

MFX:	MFAL_28260

MAIC:

MAIC_02140

MIJ:	MINS_04480

MALV:

MALV_38680

MTY:	MTOK_18320

MPSC:

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_02905(fadD32)

MSEI:

MSEDJ_06340

MFLV:

NCTC10271_00213

MCEE:

MCEL_34200

MBRM:

L2Z93_000090(fadD32)

MMON:

EWR22_27045

MGO:	AFA91_04320

MHOL:

K3U96_01635(fadD32)

MSEN:

K3U95_27530(fadD32)

MPAE:

K0O64_28155(fadD32)

MRF:	MJO55_25950(fadD32)

MDF:	K0O62_27625(fadD32)

MCRO:

MI149_27980(fadD32)

MGRO:

FZ046_04565

MAUS:

JN090_28195

MFRE:

EXE63_16675

MKR:	MKOR_32930(fadD32)

MPAK:

MIU77_01065(fadD32)

MAB:

MAB_0179

MMV:	MYCMA_0107

MABB:

MASS_0177

MABL:

MMASJCM_0181

MCHE:

BB28_00915 BB28_22820

MIZ:	BAB75_01125

MSTE:

MSTE_00178 MSTE_04632

MSAO:

MYCSP_00815 MYCSP_20825

MSAL:

DSM43276_00156

MJD:	JDM601_3262 JDM601_4118(fadD32)

MTER:

4434518_03248 4434518_04057(fadD32)

MMIN:

MMIN_15550(fadD32)

MHIB:

MHIB_34410(fadD32)

MHER:

K3U94_22480(fadD32)

MVM:	MJO54_22535(fadD32)

ASD:

AS9A_0107

CGL:	Cgl2872(Cgl2872)

CGB:	cg3179(fadD2)

CGU:	WA5_2774(FadD2)

CGT:

cgR_2761

CGS:	C624_14090

CGG:	C629_14095

CGM:	cgp_3179(fadD2)

CGJ:

AR0_13955

CGQ:	CGLAR1_13815

CGX:	SB89_13540

CEF:

CE2706

CDI:

DIP2190

CDP:	CD241_2079(fadD1)

CDH:	CDB402_2051(fadD1)

CDT:	CDHC01_2080(fadD1)

CDE:	CDHC02_2074(fadD1)

CDR:	CDHC03_2076(fadD1)

CDA:	CDHC04_2106(fadD1)

CDZ:	CD31A_2209(fadD1)

CDB:	CDBH8_2165(fadD1)

CDS:	CDC7B_2171(fadD1)

CDD:	CDCE8392_2091(fadD1)

CDW:	CDPW8_2154(fadD1)

CDV:	CDVA01_2002(fadD1)

CDIP:

ERS451417_02224(fadD1)

CJK:	jk0137(fadD1)

CUR:

cu0159

CUA:	CU7111_0165(fadD1)

CAR:	cauri_2369(fadD6)

CPU:	CPFRC_09880

CPL:	Cp3995_2007(fadD32)

CPG:	CP316_10085

CPP:	CpP54B96_1983(fadD32)

CPK:	CP1002_03280

CPQ:	CPC231_09860

CPX:	CPI19_09880

CPZ:	CpPAT10_1959(fadD32)

COR:	Cp267_2026(fadD32)

COP:	CP31_10300

COD:	Cp106_1909(fadD32)

COS:	Cp4202_1946(fadD32)

COI:	CPCIP5297_10095

COE:	CP258_10095

COU:	CP162_10080

CPSE:

CPTA_00348

CPSU:

CPTB_01181

CPSF:

CPTC_00850

CRD:	CRES_0535(fadD1)

CUL:	CULC22_02187(fadD)

CUC:	CULC809_02035(fadD)

CUE:	CULC0102_2179(fadD)

CUN:	Cul210932_2165(fadD32)

CUQ:	Cul210931_2119(fadD32)

CUZ:	Cul05146_2157(fadD32)

CUJ:	CUL131002_2074c(fadD32)

CUS:	CulFRC11_2057(fadD)

CVA:	CVAR_0253(fadD1)

CHN:	A605_13095

CCN:	H924_12080

CTER:

A606_01020

CMD:	B841_11955

CAZ:	CARG_09200

CFN:	CFAL_00845

CCG:	CCASEI_13160

CVT:	B843_12065

CGY:	CGLY_15060(fadD10)

CAX:	CATYP_09925

CII:	CIMIT_10965

CUV:	CUREI_10445

CDO:	CDOO_12570

CHM:	B842_12020

CSX:	CSING_12325

CMQ:	B840_11645

CKU:	UL82_09930

CCJ:	UL81_10680

CMV:	CMUST_14185

CEI:	CEPID_11620

CTED:

CTEST_12365

CUT:	CUTER_10400(fadD1)

CDX:	CDES_12915

CSP:	WM42_1643(fadD32)

CSTA:

CSTAT_12140

CCJZ:

ccrud_13070

CFK:	CFRA_10950

CPHO:

CPHO_11430

CFC:	CFLV_11785

CGV:	CGLAU_11445

CSTR:

CAQU:

CSPH:

CAMG:

CMIN:

NCTC10288_00197(fadD6)

CPEG:

CPELA_00945

CXE:	FOB82_04880

CEE:	CENDO_10580

CSAN:

E3227_04885

CGK:	CGERO_00945

CRF:	FRC0190_02229

CRL:	NCTC7448_00618

CCHO:

CCHOA_00620 CCHOA_00630

CPRE:

CPSO:

CSUR:

CCYS:

CMAT:

CYZ:	C3B44_10920

CKF:	I6I12_01860

CANS:

CLIA:

CPRP:

CGLU:

CUO:	CUROG_01015

CLIZ:

CSIL:

CTUB:

CLUJ:

CQN:	G7Y29_09875

CKW:	CKALI_01100

CCOE:

CETAM_12415

COK:	COCCU_13165

CZO:	IAU67_08315

CORY:

FQV43_01235

CMF:	GWO64_011270

CUW:	LH390_10835

CPOY:

GP475_11625

CACC:

CACC_11050

CFY:	I6L56_07945

CPSL:

KBP54_10105

CHIN:

J5O04_00460

CJH:	CJEDD_11125

CPSP:

CMAS:

CHEI:

CIHU:

CCOY:

CHAD:

CFG:	CFREI_13040

CAQM:

CCAW:

CAUI:

CFAC:

CFOU:

CFEU:

CAUS:

CATR:

CDUR:

CCOU:

CHAN:

CAFE:

CGF:	CGUA_12375

CGOI:

CAPP:

CBOV:

CSUE:

CBRE:

CPYR:

CRIE:

CIK:	H0194_04905

CORN:

BJP05_00970

CGP:	KBP53_10540

BFV:	C628_14285

NFA:

NFA_1880

NFR:	ERS450000_04051

NCY:	NOCYR_0144(fadD32)

NBR:	O3I_000750 O3I_001040

NNO:	NONO_c01500 NONO_c13400

NSL:	BOX37_00770 BOX37_05415

NSR:	NS506_00793 NS506_02924

NTP:	CRH09_00830 CRH09_07580

NOZ:	DMB37_21770 DMB37_22100

NOD:	FOH10_24545 FOH10_30785

NAH:	F5544_00850 F5544_08135

NAD:	NCTC11293_00924 NCTC11293_02032

NWL:	NWFMUON74_01290 NWFMUON74_58440

NIE:	KV110_00735 KV110_01050

NTC:	KHQ06_06755 KHQ06_37610

NHU:	H0264_01915 H0264_36745

NYA:	LTV02_30775 LTV02_36515

NGP:	LTT66_13570 LTT66_13900

NSPU:

IFM12276_65700 IFM12276_66300

NYU:	D7D52_10905 D7D52_25120 D7D52_33880

RHA:	RHA1_ro04064

RER:	RER_02200(fadD32)

REY:

O5Y_01110

REB:	XU06_01125

RQI:	C1M55_01130

ROP:	ROP_39420(fadD32)

ROA:	Pd630_LPD00463

RPY:	Y013_17455

RBY:	CEJ39_03850

RHB:

NY08_3917

RAV:	AAT18_01515

RHW:	BFN03_17085

RRZ:	CS378_17695

RHU:	A3Q40_03639

RHQ:	IM25_07400

RHOD:

AOT96_11685

RRT:	4535765_00220

RCR:	NCTC10994_02462

RTM:	G4H71_09110

RKO:	JWS14_22225

RGO:	KYT97_20710

ROZ:	CBI38_02235

RPSK:

JWS13_22720

RGOR:

NMQ04_00835(fadD32)

RHOP:

D8W71_02540

RHOO:

RA302_01185(fadD32)

RHOU:

KZJ41_01490

RHOW:

A4U64_23260

RHOJ:

JVH1_16135(fadD32)

RHOS:

QWW67_18830(fadD32)

RHOQ:

QWW98_18840(fadD32)

RHOY:

QNA09_25570(fadD32)

RHOH:

CPI83_27795

RHOX:

RBB84_22035(fadD32)

RFA:	A3L23_02031

RHS:	A3Q41_01332

REQ:

REQ_02040

PSOW:

ABI214_12980(fadD32)

WHR:	OG579_11360(fadD32)

GBR:

Gbro_0214

GPO:	GPOL_c04170

GOR:

KTR9_0211

GOQ:	ACH46_01180

GTA:	BCM27_01565

GOC:	CXX93_02120

GIT:	C6V83_02185

GRU:	GCWB2_00965

GOM:	D7316_03452

GAV:	C5O27_03660

GOD:	GKZ92_01285

GOS:	QAD21_01375(fadD32)

GOJ:	GR168_01500

GAM:	GII34_22565

GPD:	GII33_22080

GJI:	H1R19_00955

GOI:	LK459_07785

GHN:	MVF96_01595(fadD32)

GAMI:

IHQ52_03245(fadD32)

GMG:	NWF22_11025(fadD32)

GSI:	P5P27_20070(fadD32)

SPIN:

KV203_00930

TPR:

Tpau_0174

TSM:	ASU32_01540

TPUL:

TPB0596_02520

TSD:	MTP03_01700

SRT:

Srot_2768

DTM:	BJL86_0232

DIT:	C3V38_07675

DIZ:	CT688_01465

DPC:	A6048_01500

DLU:	A6035_01850

DKN:	NHB83_01390(fadD32)

DCD:	VYL96_01590(fadD32)

CBQ:	AL705_04190

TOY:	FO059_02180

» show all

Reference

PMID:19477415

Authors

Leger M, Gavalda S, Guillet V, van der Rest B, Slama N, Montrozier H, Mourey L, Quemard A, Daffe M, Marrakchi H

Title

The dual function of the Mycobacterium tuberculosis FadD32 required for mycolic acid biosynthesis.

Journal

Chem Biol 16:510-9 (2009)
DOI:10.1016/j.chembiol.2009.03.012

Sequence

[mtu:Rv3801c]

All links

Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (777)   
   KEGG GENES (459)   
   KEGG MGENES (299)   
   RefGene (16)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (791)   

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