Because the nucleus contains activated DNA-binding proteins, using nuclear extracts is preferable. For this reason, the version of the NoShift Assay Kit used here includes components (the ...
PELSA is a sensitive, versatile method for identifying ligand-binding proteins and sites in native systems without requiring ...
More information: Kejia Li et al, A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands, Nature Methods (2024).
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