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2021, Lithium: States of Exhaustion
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8 pages
1 file
Human bodies are in a permanent state of exchange. Through the nose and mouth, our lungs perform a continuous process of inhaling oxygen and exhaling CO2 . Our skin permanently exchanges water with the environment, releasing or receiving humidity. Blood is continuously flowing in our veins, feeding the different organs that make up the body. Electric impulses are always traveling through our nerves. Even in a state of total rest – as in profound sleep or total relaxation – the atoms in our body are continuously moving.
Philosophy Study, 2020
Starting from a philosophical perspective, which states that the living structures are actually a combination between matter and information, this article presents the results on an analysis of the bipolar information-matter structure of the human organism, distinguishing three fundamental circuits for its survival, which demonstrates and supports this statement, as a base for further development of the informational model of consciousness to a general informational model of the human organism. For this, it was examined the Informational System of the Human Body and its components from the perspective of the physics/information/neurosciences concepts, showing specific functions of each of them, highlighting the correspondence of these centers with brain support areas and with their projections in consciousness, which are: Center of Acquisition and Storing of Information (CASI) reflected in consciousness as memory, Center of Decision and Command (CDC) (decision), Info-Emotional Center (IES) (emotions), Maintenance Informational System (MIS) (personal status), Genetic Transmission System (GTS) (associativity/genetic transmission) and Info Genetic Generator (IGG) related by the body development and inherited behaviors. The Info Connection (IC), detected in consciousness as trust and confidence can explain the Near-Death Experiences (NDEs) and associated phenomena. This connection is antientropic and informational, because from the multitude of uncertain possibilities is selected a certain one, helping/supporting the survival and life. The human body appears therefore as a bipolar structure, connected to two poles: information and matter. It is argued that the survival, which is the main objective of the organism, is complied in three main ways, by means of: (i) the reactive operation for adaptation by attitude; (ii) the info-genetic integration of information by epigenetic processes and genetic transmission of information for species survival, both circuits (i) and (ii) being associated to the information pole; (iii) maintenance of the material body (defined as informed matter) and its functions, associated to the matter pole of the organism. It results therefore that the informational system of the human body is supported by seven informational circuits formed by the neuro-connections between the specific zones of the brain corresponding to the informational subsystems, the cognitive centers, the sensors, transducers and execution (motor/mobile) elements. The fundamental informational circuits assuring the survival are the reactive circuit, expressible by attitude, the epigenetic/genetic circuit, absorbing and codifying information to be transmitted to the next generations, and the metabolic circuit, connected to matter (matter pole). The presented analysis allows to extend the informational modeling of consciousness to an Informational Model of Consciousness and Organism, fully describing the composition/functions of the organism in terms of information/matter and neurosciences concepts.
Journal of Affective Disorders, 2001
We review the history of bipolar disorders from the classical Greek period to DSM-IV. Perhaps the first person who described mania and melancholia as two different phenomenological states of one and the same disease was the Greek physician of the 1st century AD, Aretaeus of Cappadocia. The modern concept of bipolar disorders was born in France, with the publications of Falret (1851) and Baillarger (1854). Emil Kraepelin, however, in 1899, unified all types of affective disorders in 'manic-depressive insanity'; in spite of some opposition, Kraepelin's unitary concept was adopted worldwide. In the 1960s, however, the rebirth of bipolar disorders took place through the publications of Jules Angst, Carlo Perris, and George Winokur, who independently showed that there exist clinical, familial and course characteristics validating the distinction between unipolar and bipolar disorders; in addition, they verified several of the corresponding opinions of the Wernicke-Kleist-Leonhard school. The concept of unipolar and bipolar disorders has further advanced in the last three decades: landmark developments include the renaissance of Kraepelin's mixed states and of Kahlbaum's and Hecker's cyclothymia and related affective temperaments, the concept of soft bipolar spectrum (Akiskal), and the distinction of schizoaffective disorders into unipolar and bipolar forms.
Journal of Affective Disorders, 2001
We review the history of bipolar disorders from the classical Greek period to DSM-IV. Perhaps the first person who described mania and melancholia as two different phenomenological states of one and the same disease was the Greek physician of the 1st century AD, Aretaeus of Cappadocia. The modern concept of bipolar disorders was born in France, with the publications of Falret (1851) and Baillarger (1854). Emil Kraepelin, however, in 1899, unified all types of affective disorders in 'manic-depressive insanity'; in spite of some opposition, Kraepelin's unitary concept was adopted worldwide. In the 1960s, however, the rebirth of bipolar disorders took place through the publications of Jules Angst, Carlo Perris, and George Winokur, who independently showed that there exist clinical, familial and course characteristics validating the distinction between unipolar and bipolar disorders; in addition, they verified several of the corresponding opinions of the Wernicke-Kleist-Leonhard school. The concept of unipolar and bipolar disorders has further advanced in the last three decades: landmark developments include the renaissance of Kraepelin's mixed states and of Kahlbaum's and Hecker's cyclothymia and related affective temperaments, the concept of soft bipolar spectrum (Akiskal), and the distinction of schizoaffective disorders into unipolar and bipolar forms.
The human organism consists of trillions of cells all working together for the maintenance of the entire organism. While cells may perform very different functions, all the cells are quite similar in their metabolic requirements. Maintaining a constant internal environment with all that the cells need to survive (oxygen, glucose, mineral ions, waste removal, and so forth) is necessary for the well-being of individual cells and the well-being of the entire body. The varied processes by which the body regulates its internal environment are collectively referred to as homeostasis.
The Bipolar Spectrum is introduced as the canopy concept for any and all entries in DSM IV. The rationale is found in exposure theory, in which the 'schizoid' side (visualized at left) is comprised of traits involved in avoiding and averting exposure, and traits to the right of center are the 'manic' elements utilized for confronting and coping with exposure. Anxieties, phobias, obsessions and the like occupy a middle ground overlapping small portions of left and right in varied combinations.
Límite (Arica)
Este artículo tiene tres partes. En la primera parte presentamos la hipótesis de G. Munévar sobre la neurociencia del trastorno bipolar. Según esta hipótesis, el trastorno bipolar es un fallo de la inhibición interhemisférica en el lóbulo frontal. Cuando la activación eléctrica del lado izquierdo supera a la del derecho, el lóbulo frontal izquierdo domina, lo que lleva a estados exagerados de euforia (u otros que también constituyen manía). La dominación en la activación del lado derecho, a su vez, conduce a estados de depresión. La literatura de neurociencia ya ofrece una gran cantidad de apoyo para esta hipótesis, como explicamos. La segunda parte describe nuestro propio estudio que utiliza la estimulación de corriente continua transcraneal (tDCS) para disminuir con éxito los estados de ánimo positivos en 25 individuos sanos. Este resultado se obtuvo al conectar los electrodos tDCS al hemisferio derecho del lóbulo frontal de los participantes mientras observaban imágenes en movimiento (de la Escala Internacional de Imágenes Afectivas), lo que concuerda con la hipótesis. La tercera parte proporciona un esquema de trabajo para un nuevo estudio potencial para establecer la hipótesis de falla de inhibición interhemisférica del lóbulo frontal en el trastorno bipolar. Este estudio usaría una nueva tecnología de imágenes cerebrales funcionales basada en qEEG: tomografía electromagnética ponderada estandarizada de baja resolución (swLORETA). Si tiene éxito, este estudio puede conducir a una terapia de estimulación eléctrica para pacientes con trastorno bipolar. Palabras Clave: Neurociencia, trastorno bipolar, estimulación de corriente continua transcraneal, tomografía electromagnética ponderada estandarizada de baja resolución.
2004
The human body is a system made of systems. The body is divided into bodily systems proper, such as the endocrine and circulatory systems, which are subdivided into many subsystems at a variety of levels, whereby all systems and subsystems engage in massive causal interaction with each other and with their surrounding environments. Here we offer an explicit definition of bodily system and provide a framework for understanding their causal interactions. Medical sciences provide at best informal accounts of basic notions such as system, process, and function, and while such informality is acceptable in documentation created for human beings, it falls short of what is needed for computer representations. In our analysis we will accordingly provide the framework for a formal definition of bodily system and of associated notions.
Psychiatric Clinics of North America, 1999
This article describes the bipolar spectrum in a h i s t o r i~a l~~ and conceptual context; then provides clinical descriptions for subtypes within this spectrum. Through case material, the authors illustrate how phenomenologic nuances can be used in support for diagnostic subtyping within this spectrum and how such subtyping could provide a more rational approach to mood stabilization in these patients. The prototypes provided should be seen as an attempt to map this vast clinical territory, rather than as definitive subclassification of bipolar spectrum disorders. For fuller description-and for much of the evidence supporting the concept of a bipolar spectrum-the reader is referred to earlier work by the authors.2, 4-6 FROM KRAEPELIN TO DSM-V K r a e~e l i n~~ envisaged a continuum between manic and depressive states. His grand vision, developed at the turn of the nineteenth century, was based on clinical observation, longitudinal course, and family history. Many patients who began with depression ended up with mania and vice versa; other depressives went as far as hypomania but not beyond; there were also patients who had a cyclical course without discernible excited episodes but who were temperamentally similar to
2004
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