[PDF][PDF] The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

J Boursier, O Mueller, M Barret, M Machado… - …, 2016 - Wiley Online Library
Several animal studies have emphasized the role of gut microbiota in nonalcoholic fatty liver
disease (NAFLD). However, data about gut dysbiosis in human NAFLD remain scarce in the …

Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state

A Blandin, I Dugail, G Hilairet, M Ponnaiah… - Cell reports, 2023 - cell.com
Adipose extracellular vesicles (AdEVs) transport lipids that could participate in the
development of obesity-related metabolic dysfunctions. This study aims to define mouse …

Effects of hydrogen sulfide on hemodynamics, inflammatory response and oxidative stress during resuscitated hemorrhagic shock in rats

F Ganster, M Burban, M de La Bourdonnaye, L Fizanne… - Critical Care, 2010 - Springer
Abstract Introduction Hydrogen sulfide (H 2 S) has been shown to improve survival in rodent
models of lethal hemorrhage. Conversely, other authors have reported that inhibition of …

Extracellular vesicles are carriers of adiponectin with insulin-sensitizing and anti-inflammatory properties

A Blandin, J Amosse, J Froger, G Hilairet, M Durcin… - Cell Reports, 2023 - cell.com
Recent evidence supporting that adipose tissue (AT)-derived extracellular vesicles (EVs)
carry an important part of the AT secretome led us to characterize the EV-adipokine profile …

Detrimental hemodynamic and inflammatory effects of microparticles originating from septic rats

S Mortaza, MC Martinez, C Baron-Menguy… - Critical care …, 2009 - journals.lww.com
Objective: Microparticles (MPs) are membrane vesicles with procoagulant and
proinflammatory properties released during cell activation and might be potentially involved …

Evidence for the involvement of VPAC1 and VPAC2 receptors in pressure‐induced vasodilatation in rodents

L Fizanne, D Sigaudo‐Roussel… - The Journal of …, 2004 - Wiley Online Library
A transient increase in skin blood flow in response to an innocuous local pressure
application, defined as pressure‐induced vasodilatation (PIV), delays the occurrence of …

Spirulina liquid extract protects against fibrosis related to non-alcoholic steatohepatitis and increases ursodeoxycholic acid

M Coué, A Tesse, J Falewée, A Aguesse, M Croyal… - Nutrients, 2019 - mdpi.com
Non-alcoholic steatohepatitis (NASH) is characterized by an excess of lipids and oxidative
stress in the liver. Spirulina was reported to possess hypolipemic and antioxidative effects …

Faeces‐derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases

L Fizanne, A Villard, N Benabbou… - Journal of …, 2023 - Wiley Online Library
The role of extracellular vesicles (EVs) from faeces (fEVs) and small circulating EVs (cEVs)
in liver diseases such as non‐alcoholic fatty diseases (NAFLD) and non‐alcoholic …

[HTML][HTML] Hemodynamic and antifibrotic effects of a selective liver nitric oxide donor V-PYRRO/NO in bile duct ligated rats

F Moal, N Veal, E Vuillemin, E Barrière… - World Journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To assess whether a liver specific nitric oxide (NO) donor (V-PYRRO/NO) would
prevent the development of portal hypertension and liver fibrosis in rats with bile duct …

GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition

E Bestion, ZM Jilkova, JL Mège… - … in Chronic Disease, 2020 - journals.sagepub.com
Background: Hepatic fibrosis is the result of chronic liver injury that can progress to cirrhosis
and lead to liver failure. Nevertheless, there are no anti-fibrotic drugs licensed for human …