The transplantation of cultured bone cells is expected to become a candidate for bone
regeneration therapy. For the clinical application of this therapy, there remain several problems to …

Glaucoma is one of the leading causes of bilateral blindness, affecting nearly 57 million people
worldwide. Glaucoma is characterized by a progressive loss of retinal ganglion cells and …

Glaucoma is the leading cause for blindness affecting 60 million people worldwide. The
optineurin (OPTN) E50K mutation was first identified in familial primary open-angle glaucoma (…

Purpose.: We determined the function of ARMS2 and HtrA1 in the choroid and retina using
transgenic (Tg) mice and evaluated the effects of mainstream cigarette smoke on these mice. …

Normal-tension glaucoma (NTG) is a heterogeneous disease characterized by retinal
ganglion cell (RGC) death leading to cupping of the optic nerve head and visual field loss at …

We identified factors associated with the empowerment of Japanese families using the Family
Empowerment Scale (FES) to contribute to the improvement of empowerment in Japanese …

An adaptor protein FRS2β inhibits epidermal growth factor-receptor (EGFR) tyrosine kinase
without being phosphorylated at tyrosine residues after EGF stimulation. Although binding to …

Dry age-related macular degeneration (AMD) accounts for over 85% of AMD cases in the
United States, whereas Japanese AMD patients predominantly progress to wet AMD or …

Leber congenital amaurosis (LCA) is a hereditary early-onset retinal dystrophy that is
accompanied by severe macular degeneration. In this study, novel compound heterozygous …

Despite the growing number of clinically practical automated cell culture systems, demand
is also increasing for more compact platforms with greater capabilities to prepare primary …