Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications
C Suparpprom, T Vilaivan - RSC Chemical Biology, 2022 - pubs.rsc.org
Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …
Chiral Peptide Nucleic Acids with a Substituent in the N-(2-Aminoethy)glycine Backbone
T Sugiyama, A Kittaka - Molecules, 2012 - mdpi.com
A peptide nucleic acid (PNA) is a synthetic nucleic acid mimic in which the sugar-phosphate
backbone is replaced by a peptide backbone. PNAs hybridize to complementary DNA and …
backbone is replaced by a peptide backbone. PNAs hybridize to complementary DNA and …
Modulable Photocatalyzed Strategies for the Synthesis of α-C-Glycosyl Alanine Analogues via the Giese Reaction with Dehydroalanine Derivates
Herein, we present the α-selective Giese reaction between pyranosyl/furanosyl bromides
and dehydroalanine analogues, which provides access to a library of highly valuable α-C …
and dehydroalanine analogues, which provides access to a library of highly valuable α-C …
Glycosyl Radical‐Based Synthesis of C‐Glycoamino Acids and C‐Glycopeptides
C Wang, R Qi, Z Xu - Chemistry–A European Journal, 2023 - Wiley Online Library
Radical‐based reactions usually exhibit excellent functional‐group compatibilities due to
their mild initiation conditions. Glycosyl radical involved C‐glycosylation modifications are …
their mild initiation conditions. Glycosyl radical involved C‐glycosylation modifications are …
Peptide nucleic acids with a structurally biased backbone. Updated review and emerging challenges
R Corradini, S Sforza, T Tedeschi… - Current topics in …, 2011 - ingentaconnect.com
Peptide nucleic acids (PNAs) are polyamidic oligonucleotide analogues which have been
described for the first time almost twenty years ago and were immediately found to be …
described for the first time almost twenty years ago and were immediately found to be …
Photoredox-catalyzed C-glycosylation of peptides with glycosyl bromides
C Li, Z Zhao, S Yu - Chinese Chemical Letters, 2024 - Elsevier
Glycosyl radicals, produced under mild photoredox conditions, show unique utility in the
preparation of C-linked glycoconjugates. We herein report the construction of C-glycosidic …
preparation of C-linked glycoconjugates. We herein report the construction of C-glycosidic …
Insights on chiral, backbone modified peptide nucleic acids: properties and biological activity
PNAs are emerging as useful synthetic devices targeting natural miRNAs. In particular 3
classes of structurally modified PNAs analogs are herein described, namely α, β and γ …
classes of structurally modified PNAs analogs are herein described, namely α, β and γ …
New peptide nucleic acid analogues: synthesis and applications
S Pensato, M Saviano, A Romanelli - Expert opinion on biological …, 2007 - Taylor & Francis
Peptide nucleic acids are oligonucleotide mimics characterised by high chemical and
enzymatic stability, high specificity and affinity toward complementary DNA/RNA. The lack of …
enzymatic stability, high specificity and affinity toward complementary DNA/RNA. The lack of …
Synthesis of β-C-galactosyl D-and L-alanines
Synthesis of β-CD-galactosyl D-and L-alanines is carried out via a highly stereoselective
Grignard reaction of glycosyl iodides, Sharpless dihydroxylation and SN2 displacement of …
Grignard reaction of glycosyl iodides, Sharpless dihydroxylation and SN2 displacement of …
Post‐Modification of Amino Acids and Peptides for the Rapid Synthesis of C‐Glycoamino Acids and C‐Glycopeptides
Z Yuan, C Zhu, Y Zhang, Y Rao - European Journal of Organic …, 2022 - Wiley Online Library
Glycoamino acids and glycoproteins, especially C‐glycoamino acids and C‐glycoproteins,
attract tremendous interests in the realm of biology and chemistry due to their wide …
attract tremendous interests in the realm of biology and chemistry due to their wide …