α‐Defensins in human innate immunity
Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …
Gallium: mechanisms
P Hoffer - J. Nucl. Med.;(United States), 1980 - osti.gov
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Show search Show menu OSTI.GOV title logo US Department of Energy Office of Scientific and …
Show search Show menu OSTI.GOV title logo US Department of Energy Office of Scientific and …
[HTML][HTML] Chlorination of endogenous amines by isolated neutrophils. Ammonia-dependent bactericidal, cytotoxic, and cytolytic activities of the chloramines.
MB Grisham, MM Jefferson, DF Melton… - Journal of Biological …, 1984 - Elsevier
Isolated human neutrophilic leukocytes were stimulated to produce hydrogen peroxide
(H2O2) and to secrete cytoplasmic granule components including myeloperoxidase into the …
(H2O2) and to secrete cytoplasmic granule components including myeloperoxidase into the …
Myeloperoxidase-dependent effect of amines on functions of isolated neutrophils.
EL Thomas, MB Grisham… - The Journal of clinical …, 1983 - Am Soc Clin Investig
Isolated neutrophilic leukocytes were incubated with primary amines and related
nitrogenous compounds. Stimulation of neutrophil oxygen (O2) metabolism with phorbol …
nitrogenous compounds. Stimulation of neutrophil oxygen (O2) metabolism with phorbol …
Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system.
DR Ambruso, RB Johnston - The Journal of clinical …, 1981 - Am Soc Clin Investig
During phagocytosis, neutrophils take oxygen from the surrounding medium and convert it to
superoxide anion (O2-) and hydrogen peroxide (H2O2). Hydroxyl radical (. OH), a …
superoxide anion (O2-) and hydrogen peroxide (H2O2). Hydroxyl radical (. OH), a …
Lactoferrin: a promoter of polymorphonuclear leukocyte adhesiveness
R Oseas, HH Yang, RL Baehner, LA Boxer - 1981 - ashpublications.org
Polymorphonuclear leukocytes (PMN) degranulate, adhere to vascular endothelium, or
aggregate to each other following exposure of the cells to high concentrations of …
aggregate to each other following exposure of the cells to high concentrations of …
Human neutrophil antimicrobial activity
Polymorphonuclear neutrophilic leukocytes (PMNs) take up opsonized microorganisms into
phagosomes that fuse with secretory granules in the PMN cytoplasm to form …
phagosomes that fuse with secretory granules in the PMN cytoplasm to form …
2 Clinically useful chelators of tripositive elements
RC Hider, AD Hall - Progress in medicinal chemistry, 1991 - Elsevier
Publisher Summary This chapter discusses the clinically useful chelators of tripositive
elements. The clinical use of chelator molecules has been synonymous with the removal of …
elements. The clinical use of chelator molecules has been synonymous with the removal of …
The microbicidal mechanisms of human neutrophils and eosinophils
RK Root, MS Cohen - Reviews of infectious Diseases, 1981 - JSTOR
Aspects of normal phagocytic cell function that have been discussed in this series include
neutro-phil formation and kinetics [1], chemotactic responses [2], digestion of …
neutro-phil formation and kinetics [1], chemotactic responses [2], digestion of …
The role of lactoferrin as an anti-inflammatory molecule
The formation of hydroxyl radical via the iron catalyzed Haber-Weiss reaction has been
implicated in phagocyte-mediated microbicidal activity and inflammatory tissue injury. The …
implicated in phagocyte-mediated microbicidal activity and inflammatory tissue injury. The …