The Business of Biotech is the pod dedicated to leaders of emerging biopharma firms. SUBSCRIBE to our new newsletter at www.bioprocessonline.com/bob. We bring you insight into organizational, finance and funding, HR, clinical, manufacturing, and regulatory challenges you’ll face as you navigate your company from an idea to success in the clinic. Each episode features guest commentary and best practices from accomplished founders and biopharma industry luminaries. The Business of Biotech is p ...
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Smart Biotech Scientist | Master Bioprocess CMC Development, Biologics Manufacturing & Scale-up, Cell Culture Innovation
David Brühlmann - CMC Development Leader, Biotech C-level Advisor, Business Strategist
The Go-to Podcast for Biotech Scientists Who Want to Master Biopharma CMC Development and Biomanufacturing. **TOP 10 LIFE SCIENCES PODCAST** Are you ready to simplify bioprocess development and scale with confidence to reduce time to market? Are you feeling overwhelmed by the complexity and guesswork of biologics development and biomanufacturing? Do you wish you had more time to enjoy the beauty of science, without worrying about failing your cell culture process development and commercializ ...
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It's one thing to listen to doom and gloom about food and fertilizer shortages, skyrocketing prices, the cost of living, or your job being outsourced overseas or eliminated due to automation. It's another thing to hear practicable, immediately actionable advice from experts who can help you reduce the fear, anxiety, and burden of these problems. Tune in now to the Surviving Hard Times Podcast with Richard Jacobs.
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Data in Biotech is a fortnightly podcast exploring how companies leverage data to drive innovation in life sciences. Every two weeks, Ross Katz, Principal and Data Science Lead at CorrDyn, sits down with an expert from the world of biotechnology to understand how they use data science to solve technical challenges, streamline operations, and further innovation in their business. You can learn more about CorrDyn - an enterprise data specialist that enables excellent companies to make smarter ...
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Diving Into Bioprocessing And Nutrition Sciences With Professor John Sheppard
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John Sheppard joins this episode to discuss the biological processes attached to beer fermentation. As a Professor in the Department of Food, Bioprocessing and Nutrition Sciences at NC State, John teaches in the Bioprocessing Science major with particular interests in upstream processes and validation. Click play and you will discover: The differen…
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116: Revolutionizing Biologics Development with Hyper Throughput Screening and AI with Jeremy Agresti - Part 2
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Send us a text The intersection of artificial intelligence and biology presents immense opportunities for transforming bioprocess development. As the biotech industry continues to evolve, data-driven innovations are critical to optimizing biologics manufacturing. High-quality datasets stand at the forefront of this transformation, empowering resear…
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Biotech Story Time With Tal Zaks, M.D. (Part 2)
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We love to hear from our listeners. Send us a message. Dr. Tal Zaks is back, along with Advancing RNA's Anna Rose Welch, for part 2 of "Story Time With Tal." On this week's episode, we turn from his time navigating medical affairs as CMO at Moderna during the COVID 19 pandemic to learn about his latest venture, an mRNA startup called Exsilio Therap…
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Talking Sustainability And Healthy Gut Health In Animals With Todd Riley Callaway
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Today we connect with Todd Riley Callaway to discuss microbiome and dairy science-related issues. Todd is an Associate Professor in the Department of Animal and Dairy Science at the University of Georgia, where he unravels “the microbial ecology of the gut in food animals, and how this can affect foodborne pathogenic bacterial populations as well a…
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Risk Mitigation With Meira GTx's Zandy Forbes, Ph.D.
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We love to hear from our listeners. Send us a message. Zandy Forbes, Ph.D. learned about business risk mitigation in the riskiest of business environments. She was a public markets healthcare investor on Wall Street for well more than a decade. Her hedge fund experience followed the Human Frontiers/Howard Hughes postdoctoral fellowship at the Skirb…
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Biotech Story Time With Tal Zaks, M.D. (Part 1)
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We love to hear from our listeners. Send us a message. Tal Zaks, M.D. was Chief Medical Officer at Moderna before, during, and immediately following the company's headline role during the COVID pandemic. If that doesn't pique your interest about the stories he can tell, this episode of the Business of Biotech surely will. Tal is now leading a new m…
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Diving Into The Intriguing World Of Plant-Fungal Interactions With Professor Katie J. Field
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Joining the podcast today is Katie J. Field, Professor of Plant-Soil Processes at The University of Sheffield. With a deep fascination for plant and fungal interactions, Katie spends her time exploring the huge impact this relationship has on the world we live in today. Presently, Katie’s research focuses on plant-fungal symbioses and their applica…
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115: Revolutionizing Biologics Development with Hyper Throughput Screening and AI with Jeremy Agresti - Part 1
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Send us a text Bioprocess development is transforming the biotech industry, driving innovations in life-changing therapies. Success hinges on simplifying complex mechanisms and adopting advanced technologies. By integrating high-throughput screening and artificial intelligence, we can streamline workflows, reduce trial-and-error, and speed up biolo…
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A $1B AI Bet With Foresite Labs' Vik Bajaj, Ph.D.
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We love to hear from our listeners. Send us a message. This past spring, Xaira Therapeutics launched with $1 billion in backing, a who's-who mashup of Silicon Valley and biopharma stars led by Marc Tessier-Lavigne in the C-suite, and a mission to develop AI-generated drugs. On this week's episode of the Business of Biotech, we're digging into the c…
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Uncharted Economic Territory on the Horizon? Consider What’s to Come with Real Estate Investor John Williams
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What might the next few months look like in terms of the economy, and how could it impact you personally? What about the next few years? This is just one of many important questions answered by today’s guest, real estate investor, and mentor, John Williams. Before the age of 30, Williams sold $100 million in real estate and has represented many hig…
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114: Weighing of Single-Use Bag Systems: Why Traditional Load Cells Are Holding You Back with Anders Tvegaard - Part 2
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Send us a text Is your bioprocess facility wasting precious time and resources on traditional weighing system calibrations? In this eye-opening episode, Anders Tvegaard, COO of Eilersen Electric, reveals how digital load cell innovation is revolutionizing bioprocess monitoring and validation. Discover why weighing systems aren't the commodity techn…
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Unlocking the Power of AI in Microscopy with Ilya Goldberg and Reese Findley
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In this episode of Data in Biotech, Ross Katz explores the transformative role of AI in microscopic imaging and life sciences with Ilya Goldberg, Chief Science Officer, and Reese Findley, an AI Data Scientist at ViQi. They discuss the cutting-edge applications of AI in automating high-content screening (HCS), enabling more efficient drug discovery,…
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113: Weighing of Single-Use Bag Systems: Why Traditional Load Cells Are Holding You Back with Anders Tvegaard - Part 1
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Send us a text What do furniture manufacturing and bioprocess weighing have in common? In this fascinating episode, Anders Tvegaard, COO of Eilersen Electric Digital Systems shares the remarkable story of how his company evolved from solving a furniture maker's wood humidity measurement problems to revolutionizing pharmaceutical manufacturing. Fift…
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Manufacturing Partnership With Life Biosciences' Jerry McLaughlin and Forge Biologics' John Maslowski
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We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Jerry McLaughlin, CEO and President at Life Biosciences returns for a visit, and he brought a friend in John Maslowski, newly-appointed CEO at Forge Biologics. We revisit progress at Life Biosciences, followed by a deep look into the gears that…
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Digging Into Sustainable Horticultural Production With Juan Carlos Díaz-Pérez
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Engaging with sustainable horticulture is both a responsible and practical way to cultivate plants. In today’s day and age, developing skills in gardening is more important than ever – and you’d be shocked by how accessible and interesting this area of expertise really is… In this episode, we sit down with horticulturist Juan Carlos Díaz-Pérez. Jua…
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112: AI Meets Biology: Why Domain Expertise Still Rules in the Age of Large Language Models with Lars Brandén - Part 2
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Send us a text Can artificial intelligence revolutionize drug development and reduce the staggering 90% failure rate in clinical trials? In this insightful episode, Lars Brandén, Director of Biology at Kolibri, shares his vision for the future of personalized medicine. Drawing from his extensive experience bridging academia and industry, Lars explo…
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111: AI Meets Biology: Why Domain Expertise Still Rules in the Age of Large Language Models with Lars Brandén - Part 1
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Send us a text In this episode, we explore the delicate dance between artificial intelligence and biological research with Lars Brandén, Director of Biology at Kolibri. From his early fascination with gene therapy to pioneering high-throughput screening centers at prestigious institutions, Lars shares invaluable insights on bridging the gap between…
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Novel Peptide Delivery With Revolo's Woody Bryan, Ph.D.
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We love to hear from our listeners. Send us a message. Revolo Biotherapeutics President and CEO Woody Bryan, Ph.D. is pushing the boundaries of peptide therapeutic delivery. On this episode of the Business of Biotech, we dig into Dr. Bryan’s transition to the CEO chair at the company and how that coincided with an aggressive strategic decision to a…
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Discussing Plant Cultivation Methods With Master Gardener Scott Wilson
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Scott Wilson joins the podcast today to discuss all things gardening-related. Scott is a Master Gardener in the state of Colorado, where he educates people both in person and with his instructional Youtube videos. Since 2004, Scott has been refining his approach to gardening and sharing his knowledge with people near and far. From starting seeds to…
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110: Spinning Like Earth: Designing Low-Shear Bioreactors for Better Cell Culture with Olivier Detournay - Part 2
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Send us a text Could Earth's gentle movements hold the key to scaling up cell therapy production? In this fascinating episode, cellular biologist and entrepreneur Olivier Detournay (CSO of Cellura) reveals how his groundbreaking bioreactor design, inspired by geophysics, is transforming difficult cell culture processes. By mimicking natural planeta…
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Reflections & Predictions: One Year of Data in Biotech with Ross Katz
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In this episode of Data in Biotech, Ross Katz reflects on what he’s learned from one year of hosting the podcast. Diving deep into the intersection of data science and biotechnology, this episode covers topics like: The need for predictive models in biotech that are grounded in real-world experimentation. The challenges of biases in model evaluatio…
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109: Spinning Like Earth: Designing Low-Shear Bioreactors for Better Cell Culture with Olivier Detournay - Part 1
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Send us a text What if the secret to growing sensitive cells lies in mimicking Earth's own movement? In this fascinating episode, cellular biologist Olivier Detournay, CSO of Cellura, reveals how studying planetary motion led to a groundbreaking bioreactor design that could transform cell therapy manufacturing. Drawing inspiration from geophysics r…
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We love to hear from our listeners. Send us a message. The notion that political influence has no place in biology appears poised for a test it hasn’t studied for. Trump administration nominations, from RFK, Jr. to HHS and Vivek Ramaswamy to the newly-proposed DOGE, are driving a storm of speculation over the implications for biotech and other life…
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Pecans: Production, Uses, Health Benefits, and More with Lenny Wells
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Pecan pie season is just around the corner! Are you ready? In this episode, Lenny Wells, professor of horticulture and extension pecan specialist at the University of Georgia, tells you everything you could know about pecans – where they come from, how they’re grown, and what it takes for them to land on your dessert plate. Press play to explore: W…
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108: From 1 Billion to 100: How AI is Cracking the Enzyme Discovery Code with David Schönauer - Part 2
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Send us a text In this captivating episode, we dive deep into the groundbreaking intersection of artificial intelligence and enzyme engineering with David Schönauer, founder and CEO of Aminoverse. From university lab benches to pioneering AI-driven enzyme discovery, David shares how his startup is transforming the biotech landscape by making enzyme…
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107: From 1 Billion to 100: How AI is Cracking the Enzyme Discovery Code with David Schönauer - Part 1
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Send us a text Ever wondered how scientists find the perfect enzyme among billions of possibilities? In this fascinating episode of the Smart Biotech Scientist podcast, host David Brühlmann sits down with David Schönauer, CEO of Aminoverse, who's revolutionizing enzyme engineering through artificial intelligence. As a biotech entrepreneur who trans…
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T-Cells For The Win With Adaptimmune's Adrian Rawcliffe
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We love to hear from our listeners. Send us a message. In August of this year, the first TCR cell therapy to be approved for use in the U.S. was greenlighted by the FDA for patients with unresectable or metastatic synovial sarcoma who have previously received chemotherapy. It marked the first new treatment for those patients in more than a decade; …
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Sustainable Agriculture: Exploring Effective Farming Methods With Andy Smith
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Joining us today to discuss sustainable agriculture and food systems is Andy Smith. Andy is the Farm Manager at Kwantlen Polytechnic University (KPU), where he works in collaboration with the Department of Sustainable Agriculture’s teaching faculty. Andy and his colleagues are putting forth an effort to expand and enhance KPU’s 20-acre urban teachi…
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106: From Proteins to Cell Therapy: Why ATMPs Aren't Just Complex Biologics with Oliver Kraemer - Part 2
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Send us a text In this insightful episode, Technical Development Leader at Flagship Pioneering Oliver Kraemer reveals why developing Advanced Therapy Medicinal Products (ATMPs) require a fundamental shift in thinking from traditional biologics development. Drawing from his extensive experience across Boehringer Ingelheim, Sanofi, and BMS, Kraemer c…
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105: From Proteins to Cell Therapy: Why ATMPs Aren't Just Complex Biologics with Oliver Kraemer - Part 1
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Send us a text In this eye-opening episode, we explore the intricate landscape of Advanced Therapy Medicinal Products (ATMPs) with Oliver Kraemer, a technical development leader at Flagship Pioneering. Drawing from his extensive experience at industry giants like BMS, Sanofi, and Boehringer Ingelheim, Oliver challenges conventional wisdom about aut…
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Serving The Underserved With Gates MRI's Claire Wagner, M.D.
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We love to hear from our listeners. Send us a message. On this episode of the Business of Biotech, Bill and Melinda Gates Medical Research Institute's (Gates MRI) Dr. Claire Wagner joins us to share insights into her work as head of Corporate Strategy and Market Access there. She shares the development of her North Star while working with the incom…
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Through the Grapevine with Fruit Crop Specialists Jim Kamas and Jacy Lewis
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Enjoy wine with dinner? Many of us do! But few consider the challenges and delicate process behind producing wine grapes and other fruit crops. Press play to learn from the experts and explore: The number one limiting factor in growing fruit crops Whether it’s better to grow grapes in greenhouses or nature (and why) How long it takes to grow wine g…
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104: One-Stop Shop vs. Specialist CDMO: A Scientist's Guide to CDMO Selection with Sigma Mostafa - Part 2
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Send us a text Want to peek behind the curtain of a leading Contract Development and Manufacturing Organization (CDMO)? In this inspiring episode, KBI Biopharma's Chief Scientific Officer Sigma Mostafa reveals the intricate world of bioprocess development and manufacturing. Sigma shares game-changing insights into accelerating biologics development…
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103: One-Stop Shop vs. Specialist CDMO: A Scientist's Guide to CDMO Selection with Sigma Mostafa - Part 1
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Send us a text In this insightful episode, we're joined by Sigma Mostafa, Chief Scientific Officer at KBI Biopharma, who shares crucial insights on selecting the right CDMO partner for biotech development. Sigma brings a unique blend of scientific rigor and practical experience to the discussion, having worked on both sides of the CDMO relationship…
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An Unanticipated Biotech Startup With OS Therapies' Paul Romness
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We love to hear from our listeners. Send us a message. Becoming a biotech CEO wasn't on Paul Romness' bingo card. He'd forged his place in the biopharma industry as a foremost public and policy affairs expert. Thirteen years at J&J, more than 5 at Amgen, and half a dozen at Boehringer Ingelheim had earned him the right to coast into a consulting gi…
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Developing Healthy And Sustainable Vegetable Farming Methods In The Southeastern U.S.
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Dr. Andre Luiz Biscaia Ribeiro da Silva joins the podcast today to discuss topics surrounding vegetable crops and organic agricultural systems. Dr. da Silva is an Assistant Professor in the Department of Horticulture at Auburn University, where he runs an extension program and conducts extensive horticultural research. With an interest in addressin…
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102: PAT Revolution: Decoding Your Bioprocess Like Never Before with Katharina Dahlmann - Part 2
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Send us a text Struggling to unravel the complexities of your bioprocess? Prepare for a paradigm shift as we dive into the world of Process Analytical Technology (PAT) with Katharina Dahlmann who is Application and PAT Expert at Hamilton. This eye-opening episode dissects how PAT is redefining biologics manufacturing, balancing its immense potentia…
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From Moderna to Dash Bio - Revolutionizing Drug Development with Dave Johnson
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In this episode of Data in Biotech, Ross Katz sits down with Dave Johnson, CEO and co-founder of Dash Bio, a next-gen drug development services company with a mission to revolutionize clinical bioanalysis and streamline drug development. Dave begins the episode by taking us back to the early research days in Moderna, where he helped lay the groundw…
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101: PAT Revolution: Decoding Your Bioprocess Like Never Before with Katharina Dahlmann - Part 1
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Send us a text Unlock the hidden potential of your bioprocess! In this eye-opening episode, David Brühlmann sits down with Katharina Dahlmann, Application and PAT Expert at Hamilton, to explore the game-changing world of Process Analytical Technology (PAT). Discover how PAT is revolutionizing biotech by providing unprecedented insights into cell be…
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Building On Pandemic Progress With Barinthus Biotherapeutics' Bill Enright
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We love to hear from our listeners. Send us a message. It might just be coincidence, but it sure seems like Bill Enright has a knack for making big moves at inopportune times, then turning the expected outcome on its ear. For example, he signed on as CEO at Altimmune when the company was struggling mightily. Enright had a turnaround plan in hand, b…
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The Joy Of Gardening: Cultivating A Regenerative And Sustainable Lifestyle With Foolproof Permaculture Strategies
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In this episode, we connect with Kareen Erbe, the Founder of Broken Ground Permaculture. Kareen is a gardening expert that has helped thousands of individuals turn their spaces into delicious and sustainable edible landscapes. As a permaculture educator, homesteader, food farmer, garden designer, and soil-builder, Kareen is committed to helping peo…
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100: From Raw Data to Actionable Insights: Unlocking the Power of Process Models with Fabian Feidl - Part 2
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Send us a text Imagine predicting your bioprocess outcomes as easily as checking the weather forecast. Sound impossible? Not anymore. In this insightful episode, we dive deep into the world of digital twins and process models with Fabian Feidl, co-founder and CTO of DataHow. Discover how these cutting-edge tools are reshaping the biotech landscape,…
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99: From Raw Data to Actionable Insights: Unlocking the Power of Process Models with Fabian Feidl - Part 1
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Send us a text Are you ready to decode the future of bioprocessing? In this eye-opening episode, we dive deep into the world of digital bioprocess development with Fabian Feidl, co-founder and CTO of DataHow. Discover how cutting-edge process models are transforming the biotech industry, bridging the gap between raw data and actionable insights. Ke…
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Obesity Tx End-Around With Skye Bioscience's Punit Dhillon
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We love to hear from our listeners. Send us a message. While the trend toward CB1 inhibition for obesity took a small hit with the release of Novo Nordisk's small molecule oral cannabinoid receptor (CB1) inverse agonist monlunabant last month, Skye Bioscience Chairman and CEO Punit Dhillon is shaking it off. He's confident that his company's antibo…
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Cutting Through the Mushroom-Growing Matrix with Chef-Turned-Farmer Jordan Jent The Best Damn Mushrooms in Texas
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Most people find growing mushrooms much harder than other food crops, but Jordan Jent discovered that they were one of the only crops he could grow successfully. Starting from scratch, he learned everything he could about the science and techniques of mushroom growing. Through a lot of trial and error, he’s mastered the craft and now produces 700 t…
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98: The Biomanufacturing Revolution: Bringing Game-changing Products to Market with James Ryall - Part 2
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Send us a text Are you ready to dive into the cutting-edge world of biomanufacturing? In this episode, strategic consultant James Ryall unveils the staggering potential of bio-based products to revolutionize industries. From cultured meat to human breast milk, discover how cells are becoming the ultimate manufacturing facilities. James shares inval…
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Chitrang Dave on Harnessing Real-Time Data to Transform MedTech and Healthcare
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This week, Chitrang Dave, Global Head of Enterprise Data & Analytics at Edwards Lifesciences, joins us to discuss the transformative power of real-time data, AI, and collaboration in medical device manufacturing and support. He and host, Ross Katz, dive into how real-time data from IoT devices is reshaping quality assurance in medtech and what the …
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97: The Biomanufacturing Revolution: Bringing Game-changing Products to Market with James Ryall - Part 1
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Send us a text In this captivating episode, host David Brühlmann welcomes James Ryall, a strategic consultant with over two decades of experience in cell biology and regenerative medicine. From his groundbreaking work in skeletal muscle research to revolutionizing cultured meat production, James shares his fascinating journey through academia and i…
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Biotech C-Suite Construction With Allan Shaw
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We love to hear from our listeners. Send us a message. Allan Shaw is back with us this week to dig into the complexities of strategic hiring in biotech. We cover strategies for the step-wise assembly of effective executive teams, the importance of aligning key hires with clinical and regulatory milestones, managing salaries in line with cash runway…
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Diving Into Offshore Aquaculture And Marine Science With Dr. Laura Tiu
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Dr. Laura Tiu joins the podcast today to discuss her work as an aquaculture specialist. Dr. Tiu is a Marine Science Extension Agent with the University of Florida Sea Grant where she plays a major role in developing sustainable offshore aquaculture and promoting environmental awareness. Dr. Tiu communicates aquaculture research to the public, and i…
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