Rizk et al., 1997 - Google Patents

Fluorimetric determination of nalidixic acid in formulations and biological fluids through ternary complex formation

Rizk et al., 1997

Document ID
9385864023622745651
Author
Rizk M
Belal F
Aly F
El-Enany N
Publication year
Publication venue
Analytical letters

External Links

Snippet

A highly sensitive and specific fluorimetric method was developed for the determination of nalidixic acid. The proposed method involves the formation of a ternary complex with Tb3+ in the presence of hexamine. The different experimental parameters were carefully studied …
Continue reading at www.tandfonline.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

Similar Documents

Publication Publication Date Title
Teng et al. Metoclopramide metabolism and determination by high‐pressure liquid chromatography
De Silva et al. Determination of flurazepam and its major biotransformation products in blood and urine by spectrophotofluorometry and spectrophotometry
Al-Kurdi et al. High performance liquid chromatography method for determination of methyl-5-benzoyl-2-benzimidazole carbamate (mebendazole) and its main degradation product in pharmaceutical dosage forms
Pritchard et al. Determination of propranolol and six metabolites in human urine by high-pressure liquid chromatography
Jin et al. Determination of quercetin in human plasma after ingestion of commercial canned green tea by semi‐micro HPLC with electrochemical detection
Toon et al. Metabolic fate of phenprocoumon in humans
Abbas et al. Spectrophotometric method for the determination of metoclopramide in pharmaceutical forms
Radomski et al. N-Oxidation of certain aromatic amines, acetamides, and nitro compounds by monkeys and dogs
Walash et al. Spectrophotometric determination of four macrolide antibiotics in pharmaceutical formulations and biological fluids via binary complex formation with eosin and spectrophotometry
Rizk et al. Fluorimetric determination of nalidixic acid in formulations and biological fluids through ternary complex formation
Cone et al. 63Ni electron-capture gas chromatographic assay for buprenorphine and metabolites in human urine and feces
Kraemer et al. Simultaneous quantification of cefotaxime, desacetylcefotaxime, ofloxacine and ciprofloxacine in ocular aqueous humor and in plasma by high-performance liquid chromatography
Battaglia et al. Absorption, disposition and preliminary metabolic pathway of 14C-rifabutin in animals and man
Midgley et al. The metabolic fate of [3H] econazole in man
Hundt et al. Post-mortem serum concentration of cantharidin in a fatal case of cantharides poisoning
CN113933399B (en) Method for separating and detecting rifampicin and related impurities in rifampicin for injection
Lamparczyk et al. RP‐HPLC method with electrochemical detection for the determination of metoclopramide in serum and its use in pharmacokinetic studies
Walash et al. A selective fluorimetric method for the determination of some 1, 4-benzodiazepine drugs containing a hydroxyl group at C-3
Shane et al. Fluorometric determination of salicylic acid in aspirin products including noninterfering, interfering, and buffered substances
Duangrat et al. Spectrofluorimetric determination of tranexamic acid in hydrogel patch formulations by derivatization with naphthalene-2, 3-dicarboxaldehyde/cyanide
Di et al. Solid-phase extraction and liquid chromatography/tandem mass spectrometry assay for the determination of pitavastatin in human plasma and urine for application to Phase I clinical pharmacokinetic studies
Strom Jr et al. Separation and quantitation of methenamine in urine by ion-pair extraction
Fang et al. Analysis of cyclosporine A and its metabolites in rat urine and feces by liquid chromatography–tandem mass spectrometry
Gao et al. HPLC-fluorescence detection for stability of harringtonine, and identification of degradation products by UPLC-Q-TOF-MS
Ahmed et al. Highly sensitive and selective high-performance liquid chromatography method for bioequivalence study of cefpodoxime proxetil in rabbit plasma via fluorescence labeling of its active metabolite