Liu et al., 2003 - Google Patents

Involvement of upstream stimulatory factors 1 and 2 in RANKL-induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation

Liu et al., 2003

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Document ID
8738568561226831538
Author
Liu Y
Shi Z
Silveira A
Liu J
Sawadogo M
Yang H
Feng X
Publication year
Publication venue
Journal of Biological Chemistry

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Tartrate-resistant acid phosphatase (TRAP) plays an important role in bone resorption. TRAP expression in osteoclasts is regulated by receptor activator of NF-κB (RANKL), a potent activator of osteoclast differentiation. However, the molecular mechanism underlying …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
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