Oh et al., 2013 - Google Patents

Radio-opaque theranostic nanoemulsions with synergistic anti-cancer activity of paclitaxel and Bcl-2 siRNA

Oh et al., 2013

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Document ID
7790092579302781865
Author
Oh M
Kim J
Lee J
Park T
Nam Y
Publication year
Publication venue
RSC advances

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The integration of therapeutic and imaging functions in a nanoscale structure is gaining increasing attention to monitor drug and gene delivery in a non-invasive real-time manner. Here we introduce radio-opaque nanoemulsions incorporating paclitaxel and Bcl-2 small …
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    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
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