Nagel et al., 2018 - Google Patents

Modular approach for theranostic polymer conjugates with activatable fluorescence: Impact of linker design on the stimuli-induced release of doxorubicin

Nagel et al., 2018

Document ID
7738599001841029393
Author
Nagel G
Tschiche H
Wedepohl S
Calderón M
Publication year
Publication venue
Journal of Controlled Release

External Links

Snippet

The introduction of cleavable motifs by dynamic covalent chemistry is widely applied in the design of drug delivery systems (DDS) to introduce controlled release properties. Since the cleavable moieties can be triggered by various exogenous or endogenous stimuli, the …
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    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
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